Augie's Case: Elevated ALT, Nodules, and Pancreatic Neoplasia Management

Augie's Case: Liver and Pancreatic Concerns Overview

Initial Consult and Diagnostics

  • Client Concern: Elevated Alanine Aminotransferase (ALT) value, which was a recurring issue for Augie.

  • Liver Fine Needle Aspirate (FNA) Cytology:

    • Cells showed moderate variation in cell size (anisocytosis) for hemipocytosis.

    • Moderate cellular difference noted (further details unclear from transcript).

  • Computed Tomography (CT) Scan Findings:

    • Revealed several soft tissue opaque radiating round nodules of varying sizes.

    • Multiple lung lesions were also identified.

Nonspecific Clinical and Laboratory Findings

  • Hematology: Nonspecific changes such as anemia and neutrophilia.

  • Chemistry:

    • Possible increases in oligomeric enzyme levels.

    • Increased UGT (Uridine Diphosphate Glucuronosyltransferase) and ALP (Alkaline Phosphatase) levels if there is bile duct leakage.

  • Radiography: While pancreatic neoplasias can be observed radiographically, further investigation is required to determine the efficacy of this diagnostic method in dogs.

General Treatment Options and Complications

Medical Treatment

  • Human Pancreatic Adenocarcinoma (Chemotherapy of Choice): Ginsenopin, often used in combination with arloplatin and