Micro 1: Classification of Microbes and The Microbiome and Health
LEARNING OUTCOMES
Classification of microorganisms: bacteria, viruses, fungi, protozoa, arthropods.
Differentiate based on phenotypic and genotypic characteristics.
Define microbiome-related terms: colonized, transient, symbiosis.
Discuss microbial components of microbiome and its development over time.
Associate microorganisms with anatomical sites.
Importance of microbiome to health and complications from disruption.
Describe restoration methods for disrupted microbiome.
MICROBIOLOGY OVERVIEW
Study of microscopic organisms, many not visible to the naked eye.
Clinically oriented applied microbiology important for patient management.
Microbial-related assessments: infection control, antimicrobial resistance, and emerging pathogens.
MICROBIOME
Mixture of organisms in various anatomical sites (skin, mouth, gut).
Colonization vs. infection: colonization does not harm the host, infection does.
Symbiosis definitions: commensal, mutualistic, parasitic.
CLASSIFICATION OF MICROORGANISMS
Bacteria: Single chromosome, no organelles.
Fungi & Protozoa: Eukaryotic, contain nuclei and organelles.
Viruses: Not cells, obligate intracellular; consist of nucleic acid and protein capsid.
Protozoan Types: Ciliated, flagellated, sporozoan, amoeboid, etc.
Helminths & Arthropods: Parasitic worms and vectors for infectious agents.
ROLE OF MICROBIOME IN HEALTH
Provides nutrients, stimulates immunity, prevents pathogen growth.
Disruption leads to risks such as opportunistic infections (e.g., C. difficile).
Restoration strategies include fecal microbiota transplantation (FMT).