Action Potential
All-or-nothing principle: Neuron fires fully or not at all.
Steps: Resting → Depolarization (Na+ in) → Repolarization (K+ out) → Refractory.
CNS vs. PNS
CNS: Brain/spinal cord (integration).
PNS: Nerves outside CNS (sensory/motor).
Neurons
Most common: Multipolar (e.g., motor).
Structure: Dendrites (receive), cell body, axon (transmit), myelin (insulate).
Types: Sensory (afferent), motor (efferent), interneurons.
Reflex Arc
Example: Knee-jerk.
Path: Receptor → Sensory neuron → Spinal cord → Motor neuron → Effector.
Senses
Vision:
Most acute: Fovea (cones).
Accommodation: Lens changes shape.
Disorders: Myopia, hyperopia, cataracts.
Taste/Smell: Chemoreceptors.
Blood
Cell types:
Erythrocytes (RBCs: O₂/CO₂).
Leukocytes (WBCs: immunity).
Platelets (clotting).
Plasma: Liquid (water, proteins, electrolytes).
Normal pH: 7.35–7.45.
Blood Vessels
Arteries: Oxygenated blood from heart.
Veins: Deoxygenated blood to heart (valves).
Capillaries: Gas/nutrient exchange.
Heart
Path: RA → RV → Lungs → LA → LV → Body.
Pacemaker: SA node.
Sounds: "Lub-dub" (valves closing).
Layers: Pericardium, myocardium, endocardium.
Pulmonary Ventilation
Inspiration: Diaphragm contracts (volume up, pressure down).
Expiration: Diaphragm relaxes (volume down, pressure up).
Key Structures
Epiglottis: Covers trachea.
Larynx: Voice box.
Pleural membrane: Reduces friction.
Lung Volumes
Tidal volume:
Normal breath (
{\approx}500
mL).
Vital capacity: Max inhale/exhale.
CO₂ Role: Regulates blood pH (bicarbonate).
Path of Food
Mouth → Esophagus → Stomach → Small intestine → Large intestine → Anus.
Key Organs
Liver: Bile, detoxifies.
Gallbladder: Stores bile.
Pancreas: Enzymes (amylase, lipase), insulin.
Absorption
Nutrients: Small intestine (villi).
Teeth
Adult: 32.
Structure: Enamel, dentin, pulp.
Terms
Bolus: Chewed food + saliva.
Chyme: Partially digested food from stomach.