Neuroscience

Chapter 3 quiz next Tuesday

Exam 2: October 6th over chapter 4,5 and 6

Research Topics due Thursday at the latest next Tuesday

• Ideas

  • Comfort Items/transitional items

  • Science of comfort items

Ionic basis of the resting membrane potential

• distribution og ions across the member and

  • Increased K+, Na+ and Ca2+ outside

• Greater negative charge intracellulary

• Distribution is maintained by the sodium potassium pump

  • Uses 70% of the brains ATP

  • Works against concentration gradients

    • K+ inside

    • Na+ outside

    • There is a unequal negative membrane potential because it is 3Na+ to 2K+

• The resting membrane potential depends on concentrations of ions inside and out and permeability of each ion

  • Mainly affected by K+ because it is the most permeable to K+ at rest

  • You can calculate resting membrane potential using the Goldman-Hodgkin-Katz equation

    • At rest it is mostly K+ leaving

• K+ channels are the major contributor of resting potential (explains relatively negative RMP)

• Know where the (K,Ca,Cl,Na) are at rest

Know and be able to sketch the ups and downs of action potentials

Information is transfers through action potentials (all or none) it continues once it is started

What triggers action potential (AP) in other systems?

• smells, chemicals, taste, touch, sound,