Integral part of healthcare, supporting physicians with timely and accurate laboratory results.
Laboratory results are crucial for diagnosing and treating patients, making laboratory professionals vital in medical settings.
Blood is the most common specimen analyzed.
Other specimens include:
Urine
Feces
Sputum
Body cavity fluids
Cerebral spinal fluid (CSF)
Seminal fluid
Essentially, any human-producible substance can be analyzed in a clinical laboratory.
Specimens are processed, analyzed, and results interpreted to help in the detection, treatment, and prevention of diseases.
Importance of accuracy and precision in measurements for reliable results.
Macroscopic observations: Visible to the naked eye (e.g., urine color).
Microscopic observations: Require a microscope to visualize (e.g., cells and bacteria).
Manual Testing: Hands-on tests performed by technicians.
Instrumented Testing: Majority of tests (60-70%) conducted using specialized equipment.
Knowledge of manual testing is essential, as instruments can malfunction.
Pathology: Study of the nature and cause of diseases.
Pathologists determine whether findings are pathogenic (disease-causing) or nonpathogenic.
Pathologists are licensed physicians specializing in pathology, often certified in anatomical or clinical lab medicine.
Medical laboratory divided into two main areas:
Clinical Laboratory: Where Medical Laboratory Technicians (MLTs) and Medical Laboratory Scientists (MLSs) work.
Anatomical Pathology: Focused on the examination of tissues and organs.
Involves the work of histology and cytology technicians who may have separate certifications.
Hematology: Study of blood.
Primarily uses the Complete Blood Count (CBC) test for:
Determining levels of red blood cells (RBCs), white blood cells (WBCs), and platelets.
Assessing hemoglobin and hematocrit.
Evaluating red blood cell indices to determine characteristics (size, maturity).
White Blood Cell Differential: Enumerates different types of white blood cells to assess infection or blood cancers like leukemia.
Chemistry: Analysis of different analytes in the plasma (e.g., glucose, electrolytes).
Microbiology: Study of infectious agents and their effects on health.
Immunology/Immunohematology: Involves blood banking and understanding immune responses.
Hemoglobin (Hgb): Protein in red blood cells responsible for oxygen transport.
Hematocrit (Hct): Percentage of RBCs in whole blood; measures volume and can indicate anemia if low.
Both tests provide insights into oxygen delivery capacities and potential tissue damage risks.