The Cell Bio 101
Cell Definition
- A cell is the basic unit of biological activity, bounded by a membrane, capable of independent reproduction.
- Organisms are unicellular or multicellular, all composed of cells.
Cell Theory
- Robert Hooke (1665): First observed dead cells; coined the term "cell."
- Mathias Schleiden (1838): All plant tissues are made of cells.
- Theodor Schwann (1839): Described similarities between plant and animal cells.
- Rudolf Virchow: Cells arise only from pre-existing cells.
Cell Structure and Components
Plasma Membrane:
- Encloses the cell, regulates material flow.
- Involved in communication and modified in some cells to form microvilli.
Endoplasmic Reticulum (ER):
- Network of membrane-enclosed spaces; consists of rough (with ribosomes) and smooth types.
- Functions in transport, storage, and protein synthesis.
Golgi Complex:
- Stack of membranes for storage, modification, and packaging of proteins; forms lysosomes.
Mitochondria:
- Powerhouses of the cell; double membrane structure, site of ATP production.
- Self-replicating organelles.
Chloroplasts:
- Found in plants; sites of photosynthesis, contain chlorophyll.
- Surrounded by two membranes, includes stroma and grana.
Vacuoles:
- Fluid-filled spaces; larger in plant cells, important for turgidity.
Microtubules and Microfilaments:
- Rod-like structures for cellular movement and shape.
Centrioles, Cilia, Flagella:
- Centrioles assist in cell division; cilia and flagella aid in movement.
Nucleus:
- Large structure containing genetic material; involved in cell growth and activity regulation.
- Contains chromatin and nucleoli for ribosomal RNA synthesis.
Prokaryotic vs. Eukaryotic Cells
- Prokaryotic Cells:
- Simple, smaller (0.1 to 0.25 cm), DNA not in a membrane, no membrane-bound organelles.
- Eukaryotic Cells:
- Larger, complex structures (10-100 cm), contain a nucleus and membrane-bound organelles.
Key Differences Between Prokaryotic and Eukaryotic Cells
| Feature | Prokaryotes | Eukaryotes |
|---|---|---|
| Cell size | Small (1-10 cm) | Large (10-100 cm) |
| Plasma membrane | Present | Present |
| Nuclear membrane | Absent | Present |
| Genetic system | Circular DNA, no histones | Linear DNA, with histones |
| Cell division | Binary fission | Mitosis |
| Sexual system | Absent in most | Present |
| Nutrition | Absorption, some photosynthesis | Absorption, ingestion, photosynthesis |
| Mitochondria | Absent | Present |
| Endoplasmic reticulum | Absent | Present |
| Golgi apparatus | Absent | Present |
| Ribosomes | Present | Present |
| Cell wall | Present (peptidoglycan) | Lacking in animals |
| Vacuoles | Absent | Present (prominent in plants) |
Differences Between Plant and Animal Cells
| Feature | Plant Cell | Animal Cell |
|---|---|---|
| Cell wall | Present | Absent |
| Chloroplasts | Present | Absent |
| Vacuole size | Large central vacuole | Small or absent vacuole |
| Centrioles | Absent | Present |