The Cell Bio 101

Cell Definition

  • A cell is the basic unit of biological activity, bounded by a membrane, capable of independent reproduction.
  • Organisms are unicellular or multicellular, all composed of cells.

Cell Theory

  • Robert Hooke (1665): First observed dead cells; coined the term "cell."
  • Mathias Schleiden (1838): All plant tissues are made of cells.
  • Theodor Schwann (1839): Described similarities between plant and animal cells.
  • Rudolf Virchow: Cells arise only from pre-existing cells.

Cell Structure and Components

  • Plasma Membrane:

    • Encloses the cell, regulates material flow.
    • Involved in communication and modified in some cells to form microvilli.
  • Endoplasmic Reticulum (ER):

    • Network of membrane-enclosed spaces; consists of rough (with ribosomes) and smooth types.
    • Functions in transport, storage, and protein synthesis.
  • Golgi Complex:

    • Stack of membranes for storage, modification, and packaging of proteins; forms lysosomes.
  • Mitochondria:

    • Powerhouses of the cell; double membrane structure, site of ATP production.
    • Self-replicating organelles.
  • Chloroplasts:

    • Found in plants; sites of photosynthesis, contain chlorophyll.
    • Surrounded by two membranes, includes stroma and grana.
  • Vacuoles:

    • Fluid-filled spaces; larger in plant cells, important for turgidity.
  • Microtubules and Microfilaments:

    • Rod-like structures for cellular movement and shape.
  • Centrioles, Cilia, Flagella:

    • Centrioles assist in cell division; cilia and flagella aid in movement.
  • Nucleus:

    • Large structure containing genetic material; involved in cell growth and activity regulation.
    • Contains chromatin and nucleoli for ribosomal RNA synthesis.

Prokaryotic vs. Eukaryotic Cells

  • Prokaryotic Cells:
    • Simple, smaller (0.1 to 0.25 cm), DNA not in a membrane, no membrane-bound organelles.
  • Eukaryotic Cells:
    • Larger, complex structures (10-100 cm), contain a nucleus and membrane-bound organelles.

Key Differences Between Prokaryotic and Eukaryotic Cells

FeatureProkaryotesEukaryotes
Cell sizeSmall (1-10 cm)Large (10-100 cm)
Plasma membranePresentPresent
Nuclear membraneAbsentPresent
Genetic systemCircular DNA, no histonesLinear DNA, with histones
Cell divisionBinary fissionMitosis
Sexual systemAbsent in mostPresent
NutritionAbsorption, some photosynthesisAbsorption, ingestion, photosynthesis
MitochondriaAbsentPresent
Endoplasmic reticulumAbsentPresent
Golgi apparatusAbsentPresent
RibosomesPresentPresent
Cell wallPresent (peptidoglycan)Lacking in animals
VacuolesAbsentPresent (prominent in plants)

Differences Between Plant and Animal Cells

FeaturePlant CellAnimal Cell
Cell wallPresentAbsent
ChloroplastsPresentAbsent
Vacuole sizeLarge central vacuoleSmall or absent vacuole
CentriolesAbsentPresent