WK 1 Contrast media

What is contrast media

  • Substance to help visualise anatomical structures and passages within the human body during medical imaging

  • Used to differentiate pathology

  • Identify vessels

  • Joints

  • Natural cavities

  • Make hollow passages more visible

How it works in x-ray

can increase or decrease the attenuation characteristics

  • Natural contrast: very similar attenuation characteristics to soft tissue - doesn’t increase or decrease radiographic appearance but fills the space - doesn’t outline structures eg. water

  • Negative contrast: decreases the attenuation characteristics and appears radiolucent on imaging eg. air

  • Positive contrast: increases the attenuation characteristic and makes structures appear more radio-opaque eg. iodinated LOCM, barium, gastrograffin

Postive contrast media

Barium sulphate

  • Needs to be mixed - alters density

  • High kvp of 100

  • Not water soluble - contraindications - risk of obstruction - can cause barium peritonitis

  • Used for:

  • Ba swallow - oesophagus

  • Ba meal - stomach

  • Ba follow through - small bowel

  • Ba enema - large bowel

  • Excretion through faeces

Gastrograffin

  • iodinated ionic HOCM - draws water in

  • Water soluble

  • diluted with water

  • 80-90 kVp used

  • Administered; orally, enema or feeding tube

  • Advantages: processes through small bowel faster than barium

  • Disadvantages: doesnt coat mucosa, dont use for risk of aspiration

  • Used when barium cannot be used

  • Contraindication; risk of aspiration - hyperosomolarity can cause acute pulmonary oedema, risk of allergy

  • Excreted through faeces

Iodinated LOCM

  • water soluble

  • low osmolar and non ionic - most common contrast media

  • used all over the body

  • genitourinary, hepatobiliary, sialography, dacrocystography

  • excetion through kidneys and urine - lots of water after the examination

  • EGFR needs to be determined before