5. biological therapy
Anti psychotic drugs
discovered in the 1950s
Most modern drugs work by blocking the effects of dopamine
The aim is to help the individual to function and to improve overall wellbeing
Typical antipsychotics and atypical antipsychotics
typical = first generation, just work on dopamine
Atypical = newer, work on a range of neurotransmitters (dopamine and serotonin)
Typical
Stop dopamine production by blocking the D2 receptors in synapses that absorb dopamine
Reducing positive symptoms
However they blocked all types of dopamine activity, so this caused side effects and may have been harmful
Atypical
Target D2 dopamine activity but not D3 receptors
Also have some effect on other neurotransmitters such as serotonin
Have fewer side effects
Brendan
Clozapine binds to dopamine receptors, as well as serotonin and glutamate receptors. This helps to improve mood and reduce depression. As less dopamine in the synapse reduces negative symptoms
Because it would enhance is mood which is will have been prescribed due to him having a high rate of schizophrenia.