Body Tissues & Nervous System Notes
Disciplines of Anatomy and Physiology
Anatomy: Study of the body's internal and external structures, and their relationships.
Physiology: Study of how these structures work as an integrated whole.
Self Regulation
Homeostasis: Maintaining a constant, stable internal environment.
Negative Feedback: A form of regulation where the result of a process inhibits that same process.
Example: Maintenance of temperature in a room using a thermostat and AC system.
Positive Feedback: When something is increasing, the body is saying to increase more
Example: Breast milk
Thermoregulation in the human body:
Components:
Set point: 37 degrees Celsius
Stimulus: body temperature
Sensor: temperature on skin
Control center: Brain
Response: Construction of the blood vessel, shivering (when body temperature is low)
Levels of Physical Organization
Complexity increases at each level.
Internal organization allows for:
Transport of nutrients and wastes
Movement
Support
Multicellularity allows for division of labor:
Tissues: Groups of cells.
Organs: Groups of different tissues with distinct functions.
Systems: Several organs working together.
Organism: Several organ systems. Humans have 11 systems.
Human Body's Four Basic Tissue Types
Epithelial
Connective
Muscle
Nervous
Epithelial Tissue
Cells always in contact with the external environment.
Functions:
Protection: Keeps body heat, waterproof.
Secretory:
Exocrine glands: Sweat glands (sweat), salivary glands (saliva).
Endocrine glands: Produce hormones to regulate growth/metabolism (e.g., thyroid).
Connection to other tissues
Cell Organization:
Simple (single layer)
Stratified (multiple layers)
Types:
Squamous
Simple: lines of blood vessels
Stratified: Skin, mouth, vagina
Cuboidal
Simple: small kidney
Stratified: sweat glands
Columnar
Simple: lining of small intensives
Stratified: mammary glands
Basement membrane: Supporting non-cellular layer that anchors to connective tissue.
Junctions:
Tight: Leak-proof (e.g., digestive tract).
Desmosomes: Flexibility (e.g., skin, heart).
Gap: Exchange of ions/water (e.g., epithelium of liver, heart, pancreas).
Connective Tissue
Cells produce ground substance (e.g., proteins & calcified material in bone).
Types:
Fibrous (loose, dense, elastic, reticular)
Specialized (cartilage, bone, blood, adipose)
Functions:
Flexibility
Insulation
Cushion
Energy storage
Strength
Transport
Fibrous:
Loose: Collagen & elastin, most common, provides flexibility.
Dense: Collagen, found in tendons, ligaments, lower skin layers, strongest.
Elastic: Organs that change shape (e.g., stomach), elastic fibers for stretch & recoil.
Reticular or Lymphoid: Internal framework of soft organs (e.g., liver, spleen, tonsils), collagen.
Specialized:
Cartilage: Protects/cushions joints, collagen & chondroblasts in lacunae, no capillaries (chondrocytes feed by diffusion through ground substance from capillaries located outside), slow to heal.
Bone: Few living cells, mostly mineral deposits of calcium & phosphate, contains blood vessels.
Blood: Cells suspended in plasma, RBC carry oxygen/CO2, WBC involved in immunity, platelets involved in clotting.
Adipose: Adipocytes, almost no ground substance, provides protection, insulation.
Muscle Tissue
Powers movement; contractile proteins within cells allow them to shorten.
Types:
Skeletal: Striated (stripe-like), regular arrangement of actin and myosin fibers, voluntary control, connects to tendons which attach to bones, fused young cells into one long cell, peripherally-located nuclei.
Cardiac: Found only in the heart, striated but under influence of its own pacemaker cells, involuntary, short, blunt-ended cells with one nucleus/cell, connected by gap junctions for electrical connections.
Smooth: Surrounds hollow organs & tubes (blood vessels, digestive tract, uterus), non-striated, involuntary, small, parallel cells with one nucleus, tapered cells, gap junctions.
Nervous Tissue
Generates and transmits electrical impulses.
Located in brain, spinal cord, and nerves.
Two cell types:
Neurons: Transmit nerve signals; 3 basic parts: cell body contains nucleus, dendrites are several cytoplasmic extensions from the cell body & receive signals from other neurons, and axons, which are long extensions that transmit electrical impulses over long distances.
Neuroglia: Non-neuronal cells surround neurons and hold them in place; for support, nourishment, insulation, & to destroy pathogens.
Organization of the Nervous System
Signal transduction from the stimulus to the spinal cord and back to the muscle that responds to such stimulus.