Pathology Flashcards
Pathology
Objectives
- Define key terms related to pathology.
- Analyze models of health and illness.
- Determine the four aspects of the biopsychosocial model of pain.
- Clarify the genetic aspects of health and illness.
- Explain the lifestyle factors that affect health.
- Describe health promotion and disease prevention and physical therapy practice implications.
- Assess epigenetics and implications for PT practice.
- Compare and contrast the increased health risks with obesity and physical therapist practice implications.
- Define stress and describe the impact of stress on the organism.
- Define and describe various psychiatric disorders.
- Discuss the impact of these disorders on the provision of healthcare services to the patient/client.
- Describe the role of the physical therapist in addressing the needs of the patient/client with these disorders.
Terms and Definitions
- Disease: Biologic/Psychologic changes leading to organ or system malfunction. Biomedical condition(s) causing disturbances in normal health. Objective changes that can occur without a person being aware of the illness.
- Illness: Perception/response of a person to not being well. Includes biologic, personal, interpersonal, & cultural reactions to disease. A person can feel ill without obvious pathologic process identified.
Illness Types
- Acute: Rapid onset & short duration, usually self-limiting, and responds to specific treatment.
- Subacute: Time course between acute & chronic, present for more than a few days but less than several months.
- Chronic:
- Permanent impairment or disability.
- Residual physical or cognitive disability.
- Need for rehabilitation and/or long-term medical management.
Incidence and Prevalence
- Incidence: Measurement of the number of new cases of a disease during a particular period of time.Measures rate of occurrence of disease which leads to calculating to probability (risk) of being diagnosed with a disease during a given period of time.
- Prevalence: Refers to the total number of cases of a disease in a population during a specific time period. References how widespread a disease has become & Indicates impact of disease on population, including length of time disease has been encountered & old/new cases.
Etiology, Clinical Manifestations, Morbidity, Premorbidity, and Comorbidity
- Etiology: Cause(s) of a disease or condition.
- Clinical Manifestations:
- Symptoms (subjective).
- Sign (Objective).
- Morbidity: Diseased state or symptom.
- Premorbidity: State of function prior to disease.
- Comorbidity: More than one disease at the same time.
Mortality
- Mortality: Death.
- Mortality rate: Number of deaths due to disease/total population.
- Taken according to age, sex, area, type of disease.
- Several types: infant, perinatal, child, maternal, crude, standardized, & age-specific
Disability (WHO Definition)
- Physical and/or cognitive condition that limits a person’s movements, senses, or activities.
- Impairments: problems in body function/structure.
- Activity limitations: Difficulty in executing a task/action.
- Participation restrictions: Difficulty with involvement in life situations.
- Health Promotion: Built on the principles of self-responsibility, nutritional awareness, stress reduction and management, and physical fitness.
- Disease Prevention: More cost-effective than treating disease.
- Primary: Remove or ↓ disease risk factors.
- Secondary: Promote early detection, initiate preventive measures for complications.
- Tertiary: Limit impact of established disease.
Disease Prevention Examples
- Primary: Good nutrition, calcium & D3 intake, regular weight bearing exercises, not smoking to prevent osteoporosis
- Secondary: Skin tests for TB, mammography, colonoscopy, routine cervical Pap smear
- Tertiary: Rehabilitation to return to highest level of function
Impact of Physical Therapy
- Earlier PT intervention leads to decreased acute care length.
- Major roles in secondary & tertiary care.
- Secondary: Wide range of settings from hospitals to preschools.
- Tertiary: highly specialized, complex, & technologically based settings.
- Prevention/Wellness Role:
- Prevention/wellness activities.
- Screening programs.
- Promotion of positive health behaviors.
Clinical Models of Health
- Biomedical:
- Model for centuries were all illness is due to disease and physiologic processes.
- Psychologic, social and spiritual influences independence of disease.
- Focuses on internal factors only.
- Illness is a deviation of the healthy state
- Biopsychosocial:
- Biologic, psychologic, and social variables: key factors in health and illness.
- Mind and body cannot be separated.
- Psychologic, cognition, emotion, motivation, with biologic/environmental factors = various health states.
- Family, community, society interactions influence health outcomes.
- Biopsychosocial Spiritual:
- Developed with advent of holistic health
- Recognizes the healing potential of faith, spirituality and religious beliefs.
- Social and spiritual support important for promotion of health, decreasing susceptibility to disease, and facilitating recovery.
- Social-Ecologic:
- Theoretic principles for understanding interrelations among diverse personal and environmental factors in health and illness.
- Health is affected by interaction between the individual, group/community, and physical, social, political environments.
Epigenetics: Behavioral, Social, Environmental Factors and Health Implications
- Epigenetics: Study of how behaviors and environment can cause changes that affect the way genes function. Based on Social-Ecological Model of Health.
- Describes heritable mechanisms that are reversible occurs without alteration of underlying DNA sequence.
- The expression of DNA and subsequent reading of the gene can be altered or manipulated.
- The mind considered "master controller" of gene expression, hence change occurs by becoming aware of individual perceptions, beliefs, and attitudes, behaviors, and lifestyle choices.
Epigenetics: Lifestyle Factors Influencing Health
- Cultural influences
- Socioeconomic status
- Generational Differences
- Adverse childhood experiences
- Physical activity
- Nutrition
- Obesity
- Smoking/tobacco use
- Alcohol/drugs
- Domestic abuse
Epigenetic Factors Influencing Health
- Individual
- Family
- Community
- Society
Physical Therapist Practice Implications
- Co-morbidity with referral to PT
- Understanding & sensitivity of symptoms
- Understanding and removal of biases
- Plan of care and goals
- Include patient in goal setting
- Repetition of intervention implications
- Recognize for referral when not diagnosed