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Movement and pleasure

  • Nucleus accumbens

    • basal ganglia- movement control circut

    • striatum- 1st imput into basal ganglia

    • nucleus accumbens (NAc)- part of straitum circut

      • recives imput from VTA dopamine

    • NAc shell

  • Basil Ganglia (big pic)

    • procedural motor learning

    • learning to play pino, sports movement aka muscle mem

    • motor learning and motor output

    • cortex (lots of info) sends converging imputs to straitum

    • I

    • I

    • I

    • Gating motor output

      • inhibits movements

      • Direct

        • diinhibits motor output (opens gait)

      • indirect

        • can disinhibit or increase inhibition

        • hyperdirect can also increase inhibition

        • Darts- hit bullsie with dart, motor plan sent to striatum, motor pathway is like did you do it right, that recalcuation movement is indirect pathway

        • hot pan- moment where you reaching for pan but you realize its hot in the middle of reaching is hyperdirect shutting down a movement in real time

      • Dopamine (SNr)

        • inhibit direct

        • excite direct

        • direct role in deciding what options the straitum considers to make it to execution

      • the striatium in the basal ganglia

        • I

      • Na Shell

        • spatial gradent from pleasure (liking) to disliking

        • from wanting/craving

        • fear advodiace

      • Nuclleus accumbens in context of basal ganglia

        • Across use there is a shift on whats activated when stimuli that prediects drug use is actibvated

      • NAc conncetivity

        • all kinds of info goes in

        • dopemgeric signal

        • thirst and food

        • motor planing