Honors Biology Review

Unit 5: Photosynthesis

  • Biotic vs. Abiotic Factors:

    • Biotic factors are living components of an ecosystem.

    • Abiotic factors are non-living components of an ecosystem.

  • Keystone Species:

    • A keystone species plays a critical role in maintaining the structure of an ecological community and affects many other organisms in an ecosystem.

    • Example: Sea otters control sea urchin populations, preventing them from destroying kelp forests.

  • Competition vs. Predation:

    • Competition: Organisms vie for the same resources (e.g., food, space).

    • Predation: One organism (predator) hunts and kills another (prey) for food.

  • Symbiosis:

    • Mutualism: Both organisms benefit.

    • Commensalism: One organism benefits, and the other is neither harmed nor helped.

    • Parasitism: One organism (parasite) benefits at the expense of the other (host).

  • Food Chains and Food Webs:

    • Food chains are linear sequences of organisms through which nutrients and energy pass as one organism eats another.

    • Food webs are interconnected food chains that represent the complex feeding relationships in an ecosystem.

    • They illustrate the flow of matter and energy within an ecosystem.

  • Food Web Components:

    • Producer: An autotroph that makes its own food (e.g., plants, phytoplankton).

    • Carnivore: An animal that eats other animals.

    • Omnivore: An animal that eats both plants and animals.

    • Scavenger: An animal that feeds on dead organisms.

    • Herbivore: An animal that eats plants.

    • Primary Consumer: An organism that eats producers (herbivore).

    • Secondary Consumer: An organism that eats primary consumers (carnivore or omnivore).

    • Tertiary Consumer: An organism that eats secondary consumers (carnivore).

  • Energy Transfer in Food Webs:

    • Only about 10% of the energy available at one trophic level is transferred to the next level; the rest is lost as heat.

    • Example: If phytoplankton have 5,926 Joules of energy, the kittiwake (a tertiary consumer) would have significantly less energy available due to energy loss at each trophic level.

  • Carbohydrates:

    • Elements: Carbon, Hydrogen, and Oxygen.

    • Monomers: Monosaccharides (e.g., glucose, fructose).

    • Functions: Energy storage and structural support.

    • Monosaccharides are simple sugars; Disaccharides are two monosaccharides joined together; Polysaccharides are many monosaccharides joined together.

    • Polysaccharides:

      • Starch: Energy storage in plants.

      • Glycogen: Energy storage in animals.

      • Cellulose: Structural component of plant cell walls.

    • Polysaccharides are formed through dehydration reactions and broken down through hydrolysis.

  • ATP (Adenosine Triphosphate):

    • ATP is the primary energy currency of the cell.

    • It stores and releases energy for cellular activities.

  • Photosynthesis Equation:

    • 6CO<em>2+6H</em>2O+LightEnergyC<em>6H</em>12O<em>6+6O</em>26CO<em>2 + 6H</em>2O + Light Energy \rightarrow C<em>6H</em>{12}O<em>6 + 6O</em>2

    • Carbon dioxide + Water + Light Energy -> Glucose + Oxygen

  • Chloroplast Structure:

    • Grana/Granum: Stacks of thylakoids.

    • Stroma: Fluid-filled space surrounding the grana.

    • Thylakoid: Membrane-bound compartment inside the chloroplast.

  • Light Reaction vs. Calvin Cycle (Dark Reaction):

    • Light Reaction:

      • Purpose: Convert light energy into chemical energy (ATP and NADPH).

      • Inputs: Water, light, NADP+, ADP.

      • Outputs: Oxygen, ATP, NADPH.

      • Location: Thylakoid membranes.

    • Calvin Cycle:

      • Purpose: Use chemical energy (ATP and NADPH) to fix carbon dioxide and produce glucose.

      • Inputs: Carbon dioxide, ATP, NADPH.

      • Outputs: Glucose, ADP, NADP+.

      • Location: Stroma.

  • Isotopes in Photosynthesis:

    • Isotopes have been used to trace the pathway of carbon dioxide and water molecules during photosynthesis.

  • Chlorophyll:

    • A pigment that absorbs light energy to initiate the light reaction.

  • NADP+ and NADPH:

    • NADP+ is an electron carrier that accepts electrons during the light reaction, forming NADPH.

  • Energized Electrons:

    • Energized electrons from chlorophyll are passed along an electron transport chain, which generates ATP and NADPH.

  • Role of Water:

    • Water is split during the light reaction to provide electrons, protons, and oxygen.

  • ATP Production in Light Reaction:

    • ATP is produced through chemiosmosis, where protons flow down a concentration gradient across the thylakoid membrane, driving ATP synthase.

  • Final Product of Calvin Cycle:

    • G3P (glyceraldehyde-3-phosphate), a three-carbon sugar that can be used to produce glucose and other organic molecules.

  • Carbon Fixation:

    • The energy of ATP and NADPH is used to convert carbon dioxide into G3P.

  • Rubisco:

    • An enzyme that catalyzes the first step of the Calvin cycle (carbon fixation).

  • Photosynthesis as an Overall Process:

    • The light and dark reactions work together to convert light energy, water, and carbon dioxide into glucose and oxygen.

  • Importance of Photosynthesis:

    • It is the foundation of most food chains, provides oxygen for the atmosphere, and removes carbon dioxide.

  • Cellular Respiration vs. Photosynthesis:

    • Photosynthesis uses carbon dioxide and water to produce glucose and oxygen.

    • Cellular respiration uses glucose and oxygen to produce carbon dioxide, water, and energy (ATP).

    • They are complementary processes.

  • Photosynthesis and Climate Change:

    • Photosynthesis helps to moderate climate change by removing carbon dioxide from the atmosphere.

Unit 6: Cellular Reproduction

  • Cell Specialization:

    • Cells differentiate to perform specific functions within an organism.

    • Important for development because it allows for the formation of complex tissues and organs.

  • Asexual Reproduction, Sexual Reproduction, and Growth/Regeneration:

    • Asexual Reproduction: A single parent produces offspring that are genetically identical to itself.

    • Sexual Reproduction: Two parents contribute genetic material to produce offspring that are genetically different from either parent.

    • Growth/Regeneration: Mitosis allows for growth, development, and repair of tissues.

  • Mitosis:

    • Important for growth, development, and repair because it produces new cells that are genetically identical to the parent cell.

  • Stages of Cell Division:

    • Interphase is the longest phase of the cell cycle, while prophase is the longest stage of mitosis.

  • Interphase:

    • G1 Phase: Cell growth and normal metabolic functions.

    • S Phase: DNA replication.

    • G2 Phase: Preparation for mitosis.

    • G0 Phase: A non-dividing state; cells exit the cell cycle and do not replicate.

  • Cell Cycle Checkpoints:

    • G1 Checkpoint: Checks for cell size, nutrients, growth factors, and DNA damage.

    • G2 Checkpoint: Checks for DNA replication completeness and DNA damage.

    • M Checkpoint: Checks for chromosome alignment during metaphase.

    • These checkpoints are important for ensuring that the cell cycle progresses correctly and that damaged cells do not divide.

  • Mitosis and Cancer:

    • Cancer is characterized by uncontrolled cell division, often due to mutations that bypass cell cycle checkpoints.

  • Eukaryotic Chromosome:

    • Chromosome: Structure containing DNA.

    • Centromere: Region where sister chromatids are joined.

    • Sister Chromatid: Identical copies of a chromosome.

  • Chromatin vs. Chromosome:

    • Chromatin: Uncondensed DNA found during interphase.

    • Chromosome: Condensed DNA found during cell division.

  • Homologous Chromosomes:

    • Pairs of chromosomes that have the same genes but may have different alleles.

    • Important in meiosis because they pair up and exchange genetic material during crossing over.

  • Haploid vs. Diploid Cells:

    • Haploid Cell: Contains one set of chromosomes (n).

    • Diploid Cell: Contains two sets of chromosomes (2n).

  • Crossing Over:

    • The exchange of genetic material between homologous chromosomes during meiosis.

    • Increases genetic variation.

  • Meiosis:

    • Meiosis needs to occur in sexually reproducing organisms to produce haploid gametes (sperm and egg cells).

    • Maintains the correct chromosome number in offspring after fertilization.

  • Mitosis vs. Meiosis:

    • Mitosis:

      • Purpose: Growth, repair, and asexual reproduction.

      • Daughter Cells: 2.

      • Ploidy: Diploid.

      • Genetic Relationship: Genetically identical to the parent cell.

    • Meiosis:

      • Purpose: Sexual reproduction.

      • Daughter Cells: 4.

      • Ploidy: Haploid.

      • Genetic Relationship: Genetically different from the parent cell and each other.

Unit 7: Patterns of Heredity (Genetics)

  • Gregor Mendel:

    • Considered the father of modern genetics.

    • Developed the basic principles of heredity through experiments with pea plants.

  • Principles of Inheritance:

    • Principle of Dominance: Some alleles are dominant and will mask the expression of recessive alleles.

    • Law of Segregation: Allele pairs separate during gamete formation.

    • Law of Independent Assortment: Alleles for different traits assort independently of one another during gamete formation.

  • Punnett Square Example:

    • Erect ears (E) is dominant over droopy ears (e).

    • If two heterozygous dogs (Ee) have puppies, the possible genotypes are EE, Ee, and ee.

    • Punnett square:

      • || E | e |

      • |---|---|

      • E | EE | Ee |

      • e | Ee | ee |

  • Genes and Alleles:

    • Gene: A segment of DNA that codes for a trait.

    • Allele: Different forms of a gene.

  • Genetic Terminology:

    • Homozygous: Having two identical alleles for a trait (e.g., EE or ee).

    • Heterozygous: Having two different alleles for a trait (e.g., Ee).

    • Dominant: An allele that masks the expression of a recessive allele.

    • Recessive: An allele that is masked by a dominant allele.

    • Genotype: The genetic makeup of an organism (e.g., EE, Ee, ee).

    • Phenotype: The physical expression of a trait (e.g., erect ears or droopy ears).

  • Dihybrid cross example:

    • Female guinea pig: heterozygous for both fur color (Dd) and coat texture (Rr)

    • Male guinea pig: dark fur (D_) and heterozygous for coat texture (Rr)

    • Dark fur color is dominant (D) and light fur (d) is recessive. Rough coat texture (R) is dominant, while smooth coat (r) is recessive.

  • Incomplete Dominance and Codominance:

    • Incomplete Dominance: The heterozygous phenotype is a blend of the two homozygous phenotypes.

    • Codominance: Both alleles are expressed equally in the heterozygous phenotype.

  • Multiple Alleles and Polygenic Traits:

    • Multiple Alleles: More than two alleles exist for a particular gene (e.g., human blood types).

    • Polygenic Traits: Traits controlled by multiple genes (e.g., human height, skin color).

  • Codominance Example:

    • Straight hair (SS) and curly hair (CC) are codominant, resulting in wavy hair (SC).

    • If a curly-haired female (CC) marries a wavy-haired male (SC), the chances of having a curly-haired child are 50%.

  • Sex-Linked Genes:

    • Genes located on the sex chromosomes (X and Y).

  • Sex-Linked Traits:

    • Occur more often in males because they only have one X chromosome.

  • Carriers:

    • Females can be carriers for sex-linked recessive traits because they have two X chromosomes; males cannot be carriers because they have only one X chromosome.

  • Sex-Linked Recessive Disease Example:

    • Colorblindness is inherited as a sex-linked recessive disease.

    • If an affected male marries a heterozygous female, there is a 50% chance of having an affected child.

  • Pedigree:

    • A diagram that shows the inheritance of a trait within a family.

  • Pedigree Analysis:

    • Used to determine the probability of having a child with a genetic disorder.

  • Pedigree Symbols:

    • Squares represent males; circles represent females.

    • Shading indicates that the individual has the trait.

  • Hemophilia Pedigree:

    • Individuals can be identified as carriers based on their position in the pedigree and the genotypes of their parents and offspring.

Unit 8: Molecular Inheritance (DNA)

  • Scientists and DNA:

    • Chargaff: Discovered that the amount of adenine (A) is equal to thymine (T) and the amount of guanine (G) is equal to cytosine (C).

    • Franklin: Used X-ray diffraction to capture the first image of DNA, revealing its helical structure.

    • Pauling: Proposed a triple-helix model of DNA (which was incorrect).

    • Watson & Crick: Developed the correct double helix model of DNA.

  • Monomer of DNA:

    • Nucleotide, composed of a deoxyribose sugar, a phosphate group, and a nitrogenous base.

  • Nitrogenous Bases:

    • Adenine (A) and Guanine (G) are purines (double-ring structures).

    • Cytosine (C) and Thymine (T) are pyrimidines (single-ring structures).

  • Base Pairing:

    • Adenine (A) pairs with Thymine (T) via two hydrogen bonds.

    • Guanine (G) pairs with Cytosine (C) via three hydrogen bonds.

  • DNA Molecule Sketch:

    • Double helix with sugar-phosphate backbone and nitrogenous bases paired in the middle.

  • Antiparallel DNA:

    • DNA strands run in opposite directions (5' to 3' and 3' to 5').

    • This arrangement is important for DNA replication.

  • DNA Replication:

    • The process of copying a DNA molecule.

  • Semiconservative Replication:

    • Each new DNA molecule consists of one original strand and one new strand.

  • Leading and Lagging Strands:

    • Leading Strand: Synthesized continuously in the 5' to 3' direction.

    • Lagging Strand: Synthesized discontinuously in short fragments (Okazaki fragments) in the 5' to 3' direction.

  • Okazaki Fragments:

    • Short DNA fragments synthesized on the lagging strand.

    • They are dealt with by DNA ligase, which joins them together.

  • Enzymes in DNA Replication:

    • DNA Helicase: Unwinds the DNA double helix.

    • DNA Polymerase: Adds nucleotides to the growing DNA strand.

    • DNA Ligase: Joins Okazaki fragments together.

    • DNA Primase: Synthesizes RNA primers to initiate DNA synthesis.

  • PCR (Polymerase Chain Reaction):

    • A technique used to amplify a specific DNA sequence.

    • Connects to DNA replication because it uses DNA polymerase to copy DNA.

  • Gel Electrophoresis:

    • A technique used to separate DNA fragments based on size.

    • Connects to PCR because it can be used to analyze the products of PCR.

    • Shortest fragments travel farthest; longest fragments travel the least far.

  • DNA vs. RNA:

    • DNA: Double-stranded, deoxyribose sugar, thymine (T).

    • RNA: Single-stranded, ribose sugar, uracil (U).

  • Protein Synthesis:

    • Essential for all life because proteins perform a wide variety of functions in cells and organisms.

  • Transcription and Translation:

    • Transcription: DNA sequence is copied into mRNA; occurs in the nucleus.

    • Translation: mRNA sequence is used to synthesize a protein; occurs in the ribosome.

  • Codon vs. Anticodon:

    • Codon: A three-nucleotide sequence on mRNA that specifies an amino acid.

    • Anticodon: A three-nucleotide sequence on tRNA that is complementary to a codon on mRNA.

  • mRNA, tRNA, RNA Polymerase, and Ribosomes in Protein Synthesis:

    • mRNA: Carries the genetic code from DNA to the ribosome.

    • tRNA: Transfers amino acids to the ribosome.

    • RNA Polymerase: Synthesizes mRNA during transcription.

    • Ribosomes: Site of protein synthesis.

  • Example of Filling in the Blanks:

    • DNA: CGT

    • mRNA: GCA

    • Amino Acid: Alanine

    • tRNA anticodon: CGU

  • Mutation:

    • A change in the DNA sequence.

    • Mutations can impact the structure of proteins by changing the amino acid sequence.

  • Point Mutations vs. Chromosomal Mutations:

    • Point Mutations: Changes in a single nucleotide (e.g., substitution, insertion, deletion).

    • Chromosomal Mutations: Changes in the structure or number of chromosomes (e.g., deletion, duplication, inversion, translocation).

  • Frameshift Mutation:

    • Insertion or deletion of nucleotides that alters the reading frame of the mRNA.

  • Beneficial and Harmful Mutations:

    • Beneficial Mutations: Can lead to new traits that improve an organism's fitness.

    • Harmful Mutations: Can lead to genetic disorders or reduced fitness.

Unit 9: Biological Evolution

  • Charles Darwin:

    • Developed the theory of evolution by natural selection.

  • Evolution:

    • Change in the heritable characteristics of biological populations over successive generations.

  • Individuals Cannot Evolve:

    • Evolution occurs at the population level, not the individual level.

  • Species:

    • A group of organisms that can interbreed and produce fertile offspring.

  • Natural Selection:

    • The process by which organisms with traits that are better suited to their environment survive and reproduce more successfully.

  • Survival of the Fittest:

    • Refers to the ability of an organism to survive and reproduce in its environment.

    • Relative fitness is the contribution an individual makes to the gene pool of the next generation relative to the contributions of other individuals.

  • Sexual Selection vs. Artificial Selection:

    • Sexual Selection: Individuals with certain traits are more likely to obtain mates (e.g., peacock feathers).

    • Artificial Selection: Humans selectively breed organisms for desired traits (e.g., dog breeds).

  • Selection is Non-Random:

    • Natural, sexual, and artificial selection are non-random processes because they favor certain traits over others.

  • Genetic Drift:

    • Random changes in allele frequencies due to chance events.

  • Founder Effect and Bottleneck Effect:

    • Founder Effect: A small group of individuals establishes a new population, leading to reduced genetic diversity.

    • Bottleneck Effect: A sudden reduction in population size due to a catastrophic event, leading to reduced genetic diversity.

  • Gene Flow:

    • The transfer of genetic material from one population to another.

  • Fossil Record:

    • Provides evidence for evolution by showing the history of life on Earth.

  • Molecular Evidence:

    • Similarities in DNA and protein sequences provide evidence for common ancestry.

  • Biogeography:

    • The study of the geographic distribution of species.

    • Distantly related species in different places may share similar traits due to convergent evolution.

  • Homologous Structures:

    • Structures that have a common ancestry but may have different functions.

  • Convergent Evolution:

    • The independent evolution of similar traits in different lineages.

  • Speciation:

    • The process by which new species arise.

  • Isolation and Speciation:

    • Geographic Isolation: Physical separation of populations.

    • Reproductive Isolation: Inability of populations to interbreed.

  • Cladogram:

    • A diagram that shows the evolutionary relationships among organisms.

  • Phylogenetic Tree:

    • Similar to a cladogram but also shows the amount of evolutionary time or change.

  • Cladogram Construction:

    • Construct a cladogram based on shared derived characters.