• Fresh, low-titer type O whole blood (FWB) is a battlefield alternative when component therapy is unavailable or failing.
• 75th Ranger Regiment ROLO (Ranger O-Low-titer) program:
• Identifies pre-screened donors with Type O, low anti-A/anti-B titers.
• Screens for blood type, infectious diseases, antibody titers before deployment.
• Donor pool is on-hand; blood drawn and transfused immediately to casualties in hemorrhagic shock.
• Regulatory status:
• In-theater collected whole blood and apheresis platelets are NOT FDA-compliant (collection environment, documentation).
• Use ONLY when FDA-approved products for 1:1:1 component therapy (PRBCs : Plasma : Platelets) are:
• Unavailable, OR
• Available but clinically ineffective.
• Ethical / practical implication – balancing immediate lifesaving need vs. regulatory compliance.
• Guiding principle – even mild hypothermia impairs coagulation ➜ exacerbates bleeding.
• Early, aggressive prevention for ALL trauma & burn casualties.
• Minimize exposure: cold ground, wind, precipitation, rotor-wash.
• Insulate beneath casualty ASAP (poncho liner, foam pad, litter insulation).
• Replace wet clothing; keep protective gear if feasible (adds insulation, prevents secondary injury).
• Active external heat:
• Place approved heating blanket on anterior torso & axillae; NEVER directly on skin.
• Enclose:
• Start with impermeable bag (e.g., HPMK heat-reflective shell).
• Upgrade to insulated hooded sleeping bag inside vapor-barrier shell when possible.
• Pre-stage kits: insulated enclosure + external heat source for hand-off / evacuation phase.
• Warm IV fluids with battery device rated to 150\ \text{mL·min}^{-1} delivering 38^{\circ}\text{C}.
• Protection continues on evacuation platforms (doors off helicopters create major convective loss).
• Shocked patients cannot self-generate heat.
• Wet clothes & helo flight exponentially increase cooling.
• Prevention is vastly easier than re-warming.
• Suspect open globe if projectile, blast, or sharp object involved.
• Rapid visual-acuity check – descending order:
• Open globe ➜ high risk of endophthalmitis ➜ give systemic antibiotics.
• Prefer moxifloxacin 400\,\text{mg} PO from Combat Wound Medication Pack (CWMP).
• If unable to take PO, use IV/IM per systemic infection protocol.
• No evidence that conjugate eye movement worsens outcome.
• Bilateral patching converts ambulatory patient into litter patient & creates psychological stress.
• Orbit = closed compartment; bleeding raises pressure ➜ optic-nerve ischemia.
• S/S: pain, proptosis, decreased vision (“bloody, blind, bulging”).
• Requires emergent evacuation; definitive field intervention = lateral canthotomy.
• Cut lateral canthal tendon, decompresses orbit.
• Must be done within minutes to save vision.
• Use electronic monitors (pulse ox, EtCO₂, BP) when gear & situation permit.
• All doses may be repeated as directed; always reassess pain & vitals.
• Contraindications for opioids (morphine, fentanyl): hypovolemic shock, respiratory distress, unconsciousness, severe TBI.
OPTION 1 – Mild/Moderate Pain, Casualty Fighting
• CWMP:
• Acetaminophen 500\,\text{mg} ×2 PO q8h (extended release =1000\,\text{mg}).
• Meloxicam 15\,\text{mg} PO once daily.
• Does NOT impair platelets (unlike other NSAIDs).
OPTION 2 – Moderate/Severe Pain, NO shock/respiratory risk
• Oral transmucosal fentanyl citrate (OTFC) 800\,\mu\text{g} between cheek & gum.
• Repeat once after 15 min if needed.
• Admin hacks: tape lozenge to casualty’s finger or safety-pin to uniform ➜ if they become obtunded, drug falls out.
• Monitor respiration; if depression occurs: establish IV, deliver naloxone 0.4\,\text{mg}, assist ventilations.
• Alternative if IV established: Morphine 5\,\text{mg} IV/IO q10 min PRN (TCCC slide shows 1.5 mg; many units use 5 mg – follow local SOP).
OPTION 3 – Moderate/Severe Pain WITH shock, respiratory risk, or likely to deteriorate
• Ketamine (favorable hemodynamic profile).
• IM/IN: 50{-}100\,\text{mg} (≈0.5{-}1\,\text{mg·kg}^{-1}) q20–30 min PRN.
• IV/IO: 30\,\text{mg} (≈0.3\,\text{mg·kg}^{-1}) over 1 min; repeat q20 min PRN.
• End-points = adequate pain control OR nystagmus.
• Safety: wide margin; maintains airway reflexes; stimulates cardiac output; rare apnea if pushed too fast (bag for a few breaths).
• Useful adjunct after opioids; safe sequential use.
• Disarm casualty after potent analgesic/dissociative agent.
• Document mental status (AVPU) pre-drug.
• Monitor ABCs continuously after opioids, ketamine, or benzos.
• Ondansetron 4\,\text{mg} ODT/IV/IM q8h PRN nausea (may repeat once at 15 min; max 8\,\text{mg}/8 h). Replaces promethazine (safer, non-sedating).
• Benzodiazepines NOT routine; reserve for procedural sedation or ketamine emergence. Avoid opioid + benzo combination.
• Avoid aspirin, ibuprofen, naproxen, ketorolac in combat zone – inhibit platelet function for 7{-}10 days.
• Meloxicam & acetaminophen spare platelet function ⇨ preferred.
• Give ASAP after life-threat conditions controlled; delays ↑ infection risk.
If casualty CAN take PO:
• Moxifloxacin 400\,\text{mg} PO once daily (from CWMP).
If casualty CANNOT take PO (shock, unconscious):
• Ertapenem 1\,\text{g} IV over 30 min OR IM once daily.
• IV prep: reconstitute vial in 10\,\text{mL} NS, transfer to 50\,\text{mL} NS.
• IM: dissolve in 3.2\,\text{mL} lidocaine 1% (no epi).
Combat Wound Medication Pack Contents (unit-dose blister):
Medication Allergy Screening
• Identify aspirin/NSAID allergies ⇨ no Meloxicam.
• Fluoroquinolone, penicillin, cephalosporin allergies need alternate antibiotics (coordinate pre-deployment).
• Control bleeding: irrigate, apply hemostatic gauze to sources.
• Cover exposed bowel with moist sterile dressing, then water-impermeable layer (transparent preferred: IV bag, food-wrap, chest seal).
• ONE gentle attempt at reduction allowed; if successful, close skin (e.g., chest-seal) to prevent re-evisceration.
• Do NOT force actively bleeding or non-reducible viscera back inside.
• Hypothermia risk ↑ (bowel evaporative loss) – monitor.
• In prolonged field care (>hours) odds of late reduction success LOW; may elect to leave external under protective dressing.
• Always inspect for additional wounds.
• Treat as trauma patient with burns (hemorrhage control & airway come first).
• Facial burns in closed space ➜ high suspicion for inhalation injury ➜ monitor SpO₂, consider early surgical airway.
• Calculate TBSA to nearest 10\%; exclude superficial (1st-degree) burns.
• Degrees:
• 1° – erythema only.
• 2° – partial-thickness (blistering).
• 3° – full-thickness (leathery, insensate).
• 4° – extends to muscle/bone.
• Dry sterile dressings; if >20\% TBSA, consider placing casualty into heat-reflective shell / Blizzard blanket (combats hypothermia & covers wounds).
• Initiate if >20\% TBSA AND IV/IO available.
• Use LR, NS, or Hextend (≤1000\,\text{mL} of Hextend; thereafter crystalloid).
• Initial hourly rate:
\text{Rate (mL·hr}^{-1}) = (\%\text{TBSA}) \times 10
• ADD 100\,\text{mL·hr}^{-1} for every 10\,\text{kg} above 80\,\text{kg} body weight.
• Example: 30\% TBSA, 100\,\text{kg} patient → 30\times10=300; +200 (two tens over 80 kg) → 500\,\text{mL·hr}^{-1}.
• If hemorrhagic shock present, prioritize damage-control resuscitation per §103.5.4.5; treat burn shock second.
• Burns ≤30\% TBSA & conscious: may use oral fluids if tactical situation allows.
• Follow TCCC triple-option analgesia (above) for burn pain.
• Routine prophylactic antibiotics NOT indicated solely for burns; give per open-wound guideline if penetrating wounds exist.
• Burn skin loses thermoregulation; combine enclosure bags, reflective shells, active warming.
• ALL TCCC interventions (tourniquet, IV, IO, chest seal) can be performed through burn skin if necessary.
• Hypothermia prevention, hemorrhage control, and analgesia form a triad that directly affects coagulation, hemodynamics, and casualty survivability.
• Eye shields, tactical eyewear, and burn dressings all underscore the preventive value of personal protective equipment (PPE).
• Whole-blood programs (ROLO) highlight need for unit-level medical planning (pre-screening, training donors) paralleling antibiotic allergy screening and CWMP issuance.
• The triple-option analgesia algorithm exemplifies escalation-of-care principles also seen in burn fluid resuscitation (oral → IV → damage-control priorities).
• Ethical implications: non-FDA-compliant products and off-label drug routes (IN ketamine) are justified under combat necessity, demanding clear SOPs and documentation.
REASSESS – REASSESS – REASSESS ➜ Every intervention above requires continuous monitoring for effectiveness & complications.