transport in humans

Circulatory system is responsible

 

If we did not have transport systems it will be difficult for everything to reach to where they need to get to

 

Circulatory system

  • System

    • A group of organisms working together to perform a particular function

  •  organs in them

    • Heart

    • Bicuspid and tricuspid can also be called AV valves

      • Atrium and ventricle valves

      • There are coronary arteries and coronary veins

        • A - give the very heart the very blood it pumps

      • myogenic

        • Only muscle that works 24/7 (ebile 25/8)

      • Acts as a pump

      • Parts

        • Septum

          • Blocks the blood so that it never combines

      • Thrombosis

        • Fancy word for clot

          • It will block the coronary artery

            • If that happens, that area will not get oxygen.

              • The muscle will die with time

      • Monitor your heart health

        • Can monitor the heart beat rate

        • Done by ECT

          • Electrocardiography

        • Listen to valves opening and closing

        • Reading pulse

 

  • Blood

    • Tissue

  • Blood vessels

 

Double and single circulation

Double

  • The blood goes through the heart twice for every single circulation through the body

  • Arteries are away the heart; veins are to the heart

  • Between heart and lungs

    • Pulmonary circuit

  • Between heart and body

    • Systemic circulation

      • Higher pressure because of the aorta

Single

  • Of a fish

 

 

Rules

  1. Direction

  2. Quality of blood

  • Arteries carry oxygenated blood

  • Veins carry deoxygenated blood

    • Exception is the pulmonary vessels

  • Left side is deoxygenated blood

  • Right side is oxygenated

  1. Pressure

  • Can be affected by distance

    • Arteries

      • High

      • Aorta

        • Highest

      • Pulmonary artery

        • Less high

    • Veins

      • Less or lower pressure

        • Can push blood up against gravity with the help of the muscles

          • Vena cava especially

 

Blood vessels

  • Role to transport blood around the body [R pump]

  • 3 types d

    • Artery

      • Thick outer wall

      • Thick layer of muscles and elastic fibres

      • Prescence of the thick muscle wall in artery

        • Withstand the pressure of the blood as a result of the surge

          • Not an ordinary flow caused by contractions of the heart (cardiac muscles)

        • Abilities to contract and relax

      • Prescence of elastic fibres

        • This allows for recoiling of the vessel after the blood has gone through

 

  • Capillary

    • Can penetrate through organs

    • Get close to the cells to transport quicker

  • Vein

 

Tissue fluid

  • When plasma is exuded from the space surrounding the cells, as soon as it touches the inside of the cell immediately it is called tissue fluid

    • Tissues should never be dry around them

  • Terms of composition

    • It is similar, the substances are same but the red blood cells are left in capillary

  • Tissue fluid enters capillary to be brought back and continues

  • Drains into lymphatic system

 

 

Lymph fluid

  • The tissue fluid that goes back and the excess enters the lymphatic vessel and forms lymph fluid

  • Lymph comes in handy because inside it contains lymphocytes

  • They have blind ends while capillaries have open ends for blood to flow through

 

Capillary bed

  • Nutrients diffuse glucose, amino acids, O2 into the cell

  • Waste material (CO2, urea,) from cell to capillary

  • They have pores

 

Plasma exuded

  • Plasma is the liquid portion of the blood

  • Prefix ex- means

  • Removed because of high pressure from the arteriole

 

Blood

  • Classified as a tissue

  • Liquid part 55%

    • Cells are suspended in It

    • Cells do not dissolve in the plasma

    • Simple soluble are found here

      • Glucose, amino acids, gases

    • Water 92%

    • Dissolved substances 8%

      • Foods

      • Salts

      • Hormones

      • Protein

      • Waste products

  • Cellular part 45%

    • Red blood cells

      • Erythrocytes (collectively)

      • Haemoglobin has affinity to O2

        • A strong attraction to O2 ensuring that O2 is carried around well

        • Contains iron

      • Lack of nucleus causing bi-concave shape

      • Live to about 4 months

    • White blood cells

      • Leukocytes

        • With a large nucleus that occupies most of the cell

      • They defend against diseases

        • Destroys unknown cells and bacteria, it kills the germ and not the disease

        • A germ causes a disease

      • All bacteria and other microbes that cause diseases are called pathogens

      • Phagocytes

        • It can change in anyway

        • Lobed nucleus

        • Larger than leukocytes

        • Carries out a process called phagocytosis

        • Grows pseudopodia

          • Pseudo means falls

          • Podia - feet

        • Close the pathogen inside the cell

        • Hydrolytic enzymes then destroy the pathogen inside the vacuole and diffuses into the space

      • Lymphocytes

        • t-cells

        • b-cells

        • Destroy the pathogens by producing antibodies

        • Antibodies are classified as a chemical/protein which destroy pathogens

    • Platelets

      • Cell fragments

      • Role of blood clotting

      • Converting fibrinogen into fibrin blood proteins

 

 

  • Capillary action

    • Goes up the x

  • Cohesive forces

  • Adhesion and that

 

 

 

 

 

Chapter 9

 

Circulatory systems                                                                                                                                            

A system of blood vessels with a pump and valves to ensure one-way flow of blood

 

  • Main transport system of all mammals

    • Network of tubes

      • Veins and arteries

    • A pump

      • Heart 

    • Blood flowing in the correct directions

      • Help from valves

 

Oxygenating the blood

  • Oxygenated blood

    • Blood containing a lot of oxygen

    • Left-hand side of the heart

    • Came from the lungs

      • Picked up from capillaries surrounding alveoli

  • Deoxygenated blood

    • Blood containing only a little oxygen

    • Oxygenated blood sent around the body

    • Cells take some oxygen

    • Deoxygenated blood brought back to the heart to become oxygenated

 

Double and single circuit systems

Double - a system in which blood passes through the heart twice on one complete circuit of the body

Single - a system in which blood passes through the heart only once on one complete circuit of the body

 

  • Double is mainly in mammals, birds and reptiles

  • Single is mainly in fish

 

  • Double has more advantages than single

    • Double

      • Low blood pressure delivered to the heart then raised again before sending to the rest of the body

      • Loses pressure when going through the body

    • Single

      • Low blood pressure continues around the fishes body

      • Blood travels slowly

    • Cells need oxygen delivered to them quickly as possible for respiration. The quicker the better. Proving double is better

 

The heart                                                                                                                                

An organ about the size of your fist that pumps blood through your body

 

 

 

 

  • Pumps blood around body

    • The cardiac muscles contract and relax regularly throughout life

 

  • Atria

    • Atrium for one

    • Upper heart chambers

  • Ventricles

    • Lower heart chambers

  • Septum

    • Separates left and right side of heart

 

  • Blood flows into atria

    • Left

      • Receives blood from pulmonary veins

    • Right

      • Receives blood from venae cavae

        • Vena cava for one

  • Blood flows out ventricles and flows in from the atria

    • Muscle walls contract and large force squeezes inwards and blood pushes far outwards

    • Left

      • Pumps into aorta

        • Largest artery

        • Blood towards the body

    • Right

      • Pumps blood into pulmonary artery

      • Taken to lungs

 

Valves

A piece of muscle that opens and closes to prevent backflow of blood

 

 

Atrioventricular valves

  • Between atria and ventricles

  • Tricuspid valve

  • Mitral valve

Semilunar valves

  • Between ventricles and arteries

  • Name is based on shape

    • Have a half-moon shape

  • Aortic valve

  • Pulmonary valve

 

Difference in muscle wall thickness

  • Atria

    • Simply receive blood then send to the ventricles

  • Ventricles

    • Pump blood around body out of the heart

    • Thicker, more muscular walls

    • Right

      • To the lungs

      • Close by

      • Less thick

      • Lower pressure

    • Left

      • To rest of the body

      • Thickest part of the heart

      • High pressure required

 

Coronary arteries

Vessels that deliver oxygenated blood to the heart muscle

 

  • Muscles in the heart are very thick

    • Making it hard for nutrients and oxygen diffuse into the muscle quick enough

    • They need a constant supply of nutrients and oxygen

      • To undergo respiration

        • Energy is released through the muscles contracting

      • Coronary arteries supply what the heart needs

 

  • Coronary arteries can get blocked

    • For some cases, cholesterol deposits build up in the walls of these blood vessels

      • Makes the artery wall stiffer and lumen narrower

      • Makes blood flow more difficult

      • Blood clots can form

    • When blocked, cardiac muscles can't receive oxygen

      • They cannot respire aerobically

      • Cannot obtain energy

      • Stop beating

      • This is called Coronary Heart Disease (CHD)

        • Common cause of illness and death

 

Preventing CHD

 

  • Most common causes of death

 

  • Stop smoking

    • Increases chances

    • Can cause other unpleasant and dangerous health problems

    • Increase formation of plaque in blood vessels

 

  • Taking care over your diet

    • Most diets are high in saturated fats which increase cholesterol

    • Meat is higher in saturated fats than plant-based foods

      • Substitute animal oils with plant oils

    • Fast food uses animal oils so eat occasionally

 

  • Regular exercise

    • Very beneficial in general for the whole body

    • Keeps you fit

    • Prevents excessive weight gain

    • Decreases blood pressure

    • Feel-good effect

      • Clears mind from worrying thoughts

      • Causes release of chemicals that increase feelings of well-being

 

Heartbeat

Rhythmic contraction and relaxation of heart muscles

 

 

 

  • Most people have 60 to 75 beats per minute when resting

  • When you hear a heart beating it is called a "lub-dub"

    • This is made from the opening and closing of valves

 

  • A way to measure

    • Pulse rate

      • Expansion and relaxation of an artery by pushing blood through it every minute

      • Your pulse rate is your heart rate

      • Pulses found wherever an artery is close enough to the skin

        • Insides of your wrist

        • Sides of your neck

        • Phones and smartwatches with that ability

    • ECG

      • Short for electrocardiograph

      • Electrodes are stuck onto a person's body

      • Electrical activity in the heart is recorded and presented as a graph

 

How the heart beats

  • Muscles in the heart contract and relax

    • Become smaller when contracting

    • Become larger when relaxing

 

  • The atrioventricular valves

    • Valve on left is called bicuspid

    • Valve on right is called tricuspid

 

  • Contraction of the different chambers in the heart

    • Atria contract

      • Increase pressure of the blood in the atria

      • Blood pushed down

      • Valves open line swinging doors to allow blood flow

    • Ventricle contract

      • Valves are pushed close

        • Tendons attached stop them from swinging up too far

      • Valves stop in a 'closed' positions

 

Blood vessels                                                                                                                                                          

Channels that carry blood throughout your body that form a closed loop that begins and ends at your heart

  • There are three main ones

    • Arteries

      • Away from the heart

      • Divide into capillaries

    • Veins

      • Capillaries join back together and eventually become veins

      • Blood towards the heart

      • Have valves

        • Keep blood flowing in the correct direction

          • Has to combat gravity in a human

    • Capillaries

      • Capillaries deliver blood containing oxygen and nutrients to close-by cells (gets to all of them)

 

Arteries

A thick-walled vessel that takes high-pressure blood away from the heart

 

  • Flows out the heart

    • Comes out in a high pressure

      • Blood forced out the heart by the ventricles

  • The need to be strong

    • Withstand high pressure

  • Does not flow smoothly through

    • Pulses through

    • Pressure is high and reduces when the ventricles relax

  • Have elastic tissue

    • To help with stretch and recoil

    • Makes the flow of blood smoother

  • You can feel arteries stretching through your pulse on wrist and neck

 

Capillaries

A tiny vessel with walls only one cell thick, that takes blood close to body cells

 

  • Very small and penetrate to every part of the body

  • No cell is very far away from a capillary

  • They take nutrients, oxygen and other materials to all cells in the body

    • They also take away waste products from cells

  • Walls are one-cell thick

 

Veins

A thin-walled vessel that takes high-pressure blood away from the heart

 

  • Much lower pressure than in arteries

    • Blood moves slower and smoother

  • Veins don't need thick, strong walls

    • If they did they would have a narrow space for blood to flow through

    • This would slow the blood even more

  • Veins have a wider lumen so the blood does not slow so much it cannot reach the heart anymore

  • Have valves

    • Stop blood flowing backwards

 

Naming blood vessels

 

  • Each organ, except the lungs, are supplied with blood

    • Arteries are away the heart; veins are to the heart

  • Liver has two blood vessels supplying it blood

    • Hepatic artery

      • Oxygenated blood

    • Hepatic portal vein

      • Brings blood from digestive system so that the liver can process the food which has been absorbed

    • Hepatic vein

      • Sends deoxygenated blood to heart

 

Blood                                                                                                                                                                          

A specialised body fluid that transports oxygen and nutrients to the cells and carries away carbon dioxide and other waste products

It is a tissue

 

  • Contains cells

  • Liquid part is called plasma

  • Most of the cellular part are red blood cells

  • A smaller number is white blood cells

  • Small cell fragments in the blood are platelets

  • Formed in the bone marrow

 

Red blood cells

Biconcave blood cells with no nucleus, which transport oxygen

 

  • Red in colour because of haemoglobin

    • A red pigment found in red blood cells, which can combine reversibly with oxygen; it is a protein

    • Haemoglobin is a protein

    • Contains iron

    • Carries oxygen

 

  • Oxyhaemoglobin

    • Combination of oxygen and haemoglobin

    • Combines where oxygen concentration is high

      • Happens in capillaries close to the alveoli

    • Releases oxygen where oxygen is low

      • Happens when capillaries are close to cells

 

  • The unusualness of red blood cells

    • No nucleus

      • More space for millions of molecules of haemoglobin

    • Shape

      • Biconcave discs

      • Flat disc that has been pinched in

      • Increases surface area

        • Speeds up rate of oxygen diffusion in and out the cell

    • Small size

      • Enables it to squeeze through the tiniest capillaries

      • Oxygen can be taken very close to every cell in the body

 

White blood cells

Blood cells with a nucleus which help to defend against pathogens

 

  • Easier to recognise because they have a nucleus

  • Often quite large

  • Can move around

    • Squeeze out through walls of blood capillaries to where they are needed

  • Fight pathogens

    • Disease-causing microorganisms

  • Clear up an dead body cells

  • Some destroy pathogens by engulfing them and digesting them

    • Phagocytosis

    • Phagocytes

      • Lobed nucleus

  • Other produce molecules called antibodies

    • Fix onto pathogens and destroy them

    • Lymphocytes

      • Large, round nucleus that almost fills the cell

 

Platelets

Tiny cell fragments present in blood, which help with clotting

 

  • No nucleus

  • Made in bone marrow

  • Involved in blood clotting

    • Stop pathogens from entering the body through cuts in skin

    • Provides a barriers against entry of bacteria

    • Prevents blood loss

 

  • Plasma has fibrinogen

    • A soluble protein

  • When a blood vessel breaks

    • Plates released make the fibrinogen change into an insoluble protein called fibrin

      • Forms fibres

      • Pile onto each other to form a mesh-like structure to seal the wound

      • Blood gets trapped in the mesh

  • Platelets stick together to form clumps

    • Fibres trapped in red blood cells clump together to form a blood clot

 

Plasma

Liquid part of blood

 

  • Mostly water

  • Many things are dissolved into it

    • Glucose, amino acids, mineral ions, etc.

  • Transports hormones and waste products

 

Component

Source

Destination

Notes

Water

Absorbed in small intestine and colon

All cells

Excess is removed by kidneys

Proteins [fibrinogen and antibodies]

Fibrinogen from liver

Antibodies from lymphocytes

Remain in blood

Helps with clotting

Antibodies kill invading pathogens

Lipids [cholesterol and fatty acids]

Absorbed  in ileum

From fat reserves in the body

To the liver for breakdown

To respiring cells as energy source

Breakdown of fat yields energy

High concentration increases risk of heart problems

Carbohydrates [glucose]

Absorbed in ileum

Breakdown of glycogen in liver

Energy release by respiration

Excess glucose converted to glycogen

Excretory substances [urea]

Produced by amino acids deamination from liver

To kidneys

Removed and dissolved with water from urine

Mineral ions

Absorbed in ileum

To all cells

Excess excreted by kidneys

Hormones

Secreted into blood

To all parts of the body

Only affect target cells

Dissolved gases

Released from process of respiration

To the lungs

Most carried is hydrogen carbonate ions