Research Design and Biological Basis Notes

Research Design

  • Hypothesis: A tentative explanation that must be falsifiable.

  • Operational Definition: A clear, precise, and quantifiable definition of variables to allow replication and reliable data collection.

  • Qualitative Data: Descriptive data (e.g., eye color).

  • Quantitative Data: Numerical data, ideal for statistics.

  • Population: The entire group to which the research could apply.

  • Sample: The specific subset of the population chosen for the study.

Research Designs

Correlation
  • Definition: Identifies the relationship between two variables.

  • Advantage: Useful when experiments are unethical.

  • Disadvantage: Correlation does not equal causation.

    • Directionality Problem: Uncertainty about which variable causes the other (e.g., depression and low self-esteem).

    • Third Variable Problem: A different variable is responsible for the observed relationship (e.g., ice cream sales and murder rates).

  • Positive Correlation: Variables increase or decrease together.

  • Negative Correlation: As one variable increases, the other decreases.

  • Strength of Correlation: The closer the absolute value is to 1, the stronger the relationship, regardless of the sign. Cannot be < or > than 1.

  • Graphical Representation: Stronger relationships appear as tighter clusters on a graph.

Experiments
  • Definition: Purposefully manipulate variables to determine cause and effect.

  • Advantage: Establishes cause and effect.

  • Disadvantage: Can be unethical or too artificial.

    • Independent Variable: The variable altered by the researcher.

      • Experimental Group: Receives the treatment (part of the IV); can have multiple experimental groups.

      • Control Group: Receives a placebo or baseline treatment (part of the IV); can only have one control group.

    • Dependent Variable: The variable measured; dependent on the independent variable.

  • Placebo Effect: An effect caused by the placebo itself.

  • Double-Blind Study: Neither the participant nor the experimenter knows the condition to which people are assigned.

  • Single-Blind Study: Only the participant is blind; used when the experimenter cannot be blind.

  • Confound: An error or flaw accidentally introduced into the study.

  • Random Assignment: Assigning participants to control or experimental groups randomly to increase the chance of equal representation.

Other Study Types
  • Naturalistic Observation: Observing people in their natural settings.

    • Advantage: Real-world validity.

    • Disadvantage: No cause and effect can be established.

  • Case Study: Studying one person in great detail.

    • Advantage: Collects lots of information.

    • Disadvantage: No cause and effect can be established.

  • Meta-Analysis: Combines multiple studies to increase sample size and examine effect sizes.

Statistics

  • Descriptive Stats: Show the shape of the data.

    • Measures of Central Tendency:

      • Mean: Average, best used in normal distribution.

      • Median: Middle number, best used in skewed distribution.

      • Mode: The number that occurs most often.

      • Bimodal: Two modes, usually indicating good and bad scores.

  • Skews:

    • Negative Skew: The mean is to the left, and the mode is to the right.

    • Positive Skew: The mean is to the right.

  • Measure of Variation:

    • Range: Distance between the smallest and largest numbers.

    • Standard Deviation: Average amount the scores are spread from the mean; a bigger number indicates more spread.

  • Inferential Statistics: Establishes significance.

    • Statistical Significance: Results are not due to chance; the experimental manipulation caused the difference in means.

    • P-value: p<.05 indicates statistical significance; the smaller, the better.

    • Effect Size: Data has practical significance; bigger is better.

Ethical Guidelines (IRB Approval Needed for People)

  • Confidentiality: Names are kept secret.

  • Informed Consent: Participants must agree to be part of the study.

  • Informed Assent: Minors and their parents must agree.

  • Debriefing: Participants must be told the true purpose of the study, especially after deception.

  • Deception: Must be warranted.

  • No Harm: No mental or physical harm should come to participants.

Additional Vocabulary

  • Surveys: Usually turned into correlation.

    • Self-Report Bias: Errors when collecting survey data.

      • Social Desirability: People lie to look good.

      • Wording Effects: How a question is framed can impact answers.

  • Random Sample (Selection): Everyone has a chance to take part; increases generalizability.

  • Representative Sample: Sample mimics the general population.

  • Convenience Sample: Select participants on availability; less representative and less generalizable.

  • Sampling Bias: Sample isn't representative due to convenience sampling.

  • Cultural Norms: Behaviors of a particular group can influence research results.

  • Experimenter Bias/Participant Bias: Experimenter/participant expectations influence the outcome.

  • Cognitive Bias: Bias in thinking/judgment.

    • Confirmation Bias: Find information that supports preexisting beliefs.

    • Hindsight Bias: "I knew it all along."

    • Overconfidence: Overestimate our knowledge/abilities.

    • Hawthorne Effect: People change behavior when watched.

  • Research needs peer review and adequate sample sizes.

Biological Basis Pillar

  • NT = neurotransmitter, AP = action potential, NS = nervous system

Heredity vs Environment

  • Evolutionary Psychology: Study how natural selection influences behavior.

  • Heredity (Nature): How genes influence behavior.

  • Environment (Nurture): How outside situations influence behavior (e.g., school).

  • Nature vs. Nurture: Answer is both.

  • Twin/Adoption Studies:

    • Genetics: Identical twins will have a higher percentage of also developing a disease.

    • Environment: Identical twins raised in different environments show differences.

Nervous System

  • Central NS: Brain and spinal cord.

  • Peripheral NS: Rest of the NS relays to the Central NS.

    • Somatic NS: Voluntary movement; has sensory and motor neurons.

    • Autonomic NS: Involuntary organs (heart, lungs, etc.).

      • Sympathetic NS: Fight/flight (generally activates, exception digestion).

      • Parasympathetic NS: Rest/digest (generally inhibits, exception digestion).

Neuron and Neural Firing

Neuron parts are described in the text.

  • Neuron: Basic cell of the NS.

    • Dendrites: Receive incoming NTs.

    • Axon: AP travels down this.

    • Myelin Sheath: Speeds up AP down axon, protects axon.

    • Synapse: Gap between neurons.

  • Sensory Neurons: Receive sense signals from the environment and send signals to the brain.

  • Motor Neurons: Signals to move, send signals from brain.

  • Interneurons: Cells in spinal cord/brain responsible for reflex arc.

  • Glia: Support cells that give nutrients and clean up around neurons.

Neurons Fire with an Action Potential

Ions move across the membrane, sending an electrical charge down the axon.

  • Resting Potential: Neuron maintains a 70mv-70mv charge when not doing anything.

  • Depolarization: The charge of neuron briefly switches from negative to positive, triggers the AP.

  • Threshold of Depolarization: Stimulus strength must reach this point to start the AP.

  • All or Nothing Principle: Stimulus must trigger the AP past its threshold but does not increase the intensity or speed of the response.

  • Refractory Period: Neuron must rest and reset before it can send another AP.

Neurotransmitters (NT)

Chemicals released in the synaptic gap, received by neurons, and classified as excitatory or inhibitory.

  • GABA: Major inhibitory NT.

  • Glutamate: Major excitatory NT.

  • Dopamine: Reward (short term) & fine movement; in hypothalamus, associated with addiction.

  • Serotonin: Moods (long-term), emotion, sleep; in amygdala, too little assoc. w/ depression.

  • Acetylcholine (ACh): Memory and movement; in hippocampus, assoc. w/ Alzheimer's.

  • Norepinephrine: Sympathetic NS; too little assoc. w/ depression.

  • Endorphins: Decrease pain.

  • Substance P: Pain regulation (abnormality increases pain and inflammation).

Hormones

If not in the nervous system, it's a hormone.

  • Oxytocin: Love, bonding, childbirth, lactation.

  • Adrenaline: Fight/flight.

  • Leptin: Makes you full (stops hunger).

  • Ghrelin: Makes you hungry (turns you into a gremlin).

  • Melatonin: Sleep.

  • Reflex Arc: Important stimuli skips the brain and routes through the spinal cord for immediate reactions.

  • Agonist: Drug that mimics a NT.

  • Antagonist: Drug that blocks a NT.

  • Reuptake: Unused NTs are taken back up into the sending neuron. Antidepressants cause reuptake inhibition.

Psychoactive Drugs

  • Depressants: Decrease NS activity (alcohol).

  • Stimulants: Increase NS activity (caffeine & cocaine).

  • Hallucinogens: Hallucinations and altered perceptions (Marijuana).

  • Opioids: Relieve pain (endorphin agonists) (heroin).

  • Tolerance: Needing more of a drug to achieve the same effects.

  • Addiction: Must have it to avoid withdrawal symptoms.

  • Withdrawal: Symptoms associated with sudden stoppage.

The Brain

  • Cerebellum: Movement, balance, coordination, procedural memory.

  • Brainstem/Medulla: Vital organs (HR, BP, breathing).

  • Reticular Activating System: Alertness, arousal, sleep, eye movement.

  • Cerebral Cortex: Outer portion of the brain, higher-order thought processes; includes limbic system, lobes, corpus callosum.

Limbic System
  • Amygdala: Emotions, fear.

  • Hippocampus: Episodic and semantic memory.

  • Hypothalamus: Reward/pleasure center, eating behaviors, link to the endocrine system, homeostasis.

  • Thalamus: Relay center for all senses but smell.

  • Pituitary Gland: Talks with endocrine system and hypothalamus; releases hormones.

Lobes

Brain lobes are described in the text..

  • Occipital Lobe: Vision.

  • Frontal Lobe: Decision-making, planning, judgment, movement, personality, language, executive function.

    • Prefrontal Cortex: Front of the frontal lobe; executive function.

    • Motor Cortex: Back of the frontal lobe; map of our motor receptors; controls skeletal movement.

  • Parietal Lobe: Sensations and touch; controls association areas.

    • Somatosensory Cortex: Map of our touch receptors.

Research Design

  • Hypothesis: A testable explanation that can be proven wrong.

  • Operational Definition: How you'll measure variables clearly, so others can repeat your study.

  • Qualitative Data: Descriptive data (like colors or feelings).

  • Quantitative Data: Numerical data (numbers), good for stats.

  • Population: The whole group you're interested in.

  • Sample: A smaller group from the population that you study.

Research Designs
Correlation
  • Definition: Shows if two things are related.

  • Advantage: Useful when you can't do experiments for ethical reasons.

  • Disadvantage: Just because two things are related doesn't mean one causes the other.

    • Directionality Problem: Not sure which thing is causing the other.

    • Third Variable Problem: Something else might be causing both things.

  • Positive Correlation: Both things go up or down together.

  • Negative Correlation: As one thing goes up, the other goes down.

  • Strength of Correlation: The closer to 1 (positive or negative), the stronger the relationship. It cannot be.

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