psych 1

psych in 3 processes

“the scientific study of behavior and mental processes”

scientific

  • answering questions objectively based on observable facts, data, established methods

    behavior

  • observable actions

    mental processes

  • thoughts, feelings, sensations, perceptions, etc.


root of psych→ philosophy

  • the nature vs nurture argument

Plato

  • nativism

  • certain knowledge is innate

Aristotle

  • philosophical empiricism

  • all knowledge is gained from experience

Rene Descartes

  • dualism

  • mind + body are separate interacting entities

  • materialism formed as a counterargument towards this→ mind is what the brain/body does


founding of psychology

  • Wilhelm Wundt

  • uses scientific methods to study psychological processes

  • writes first psychology textbook

  • establishes first psychology research laboratory→ 1879


Structuralism

Wilhelm Wundt

  • promotes belief experimental methods should be used to study mental processes

Edward Tichener

  • student of Wundt

  • complex conscious experiences can be broken down into elemental parts/structures


Functionalism

  • advocated by William James and influenced by Darwin

  • focuses on how behaviors and mental processes function to allow people and animals to adapt to their environment and how these traits have evolved

William James

  • Harvard psychologist influential in establishing psychology in the United States

Charles Darwin

  • Behavioral and mental adaptations evolve via natural selection


Psychoanalysis

  • Sigmund Freud

  • unconscious mental processes shape feelings, thoughts, and behaviors

  • emphasis on childhood experiences + early relationships

  • therapy focuses on the relationship formation between therapist and patient, resistance to therapy, identification of defense mechanisms, and can involve techniques such as dream interpretation


Behaviorism

  • psychology redefined as the scientific study of observable behavior

Ivan Pavlov

  • develops the principles of classical conditioning

John Watson

  • extends behavioral psychology to focus human behavior

B.F. Skinner

  • develops the principles of operant conditioning

  • reinforcement/punishment shapes behavior


Humanistic Psychology

  • Carl Rogers

  • Abraham Maslow

  • focused on the positive potential of human beings

  • reaction to negative implications of Freudian and emphasis on external influences of the behaviorist school

  • emphasis on factors that contribute to well-being, happiness, and flourishing


Cognitive Psychology

  • return to an emphasis on mental processes and how they influence behavior

  • scientific study of perception, memory, thought, and intelligence

  • influenced by the emergence of the computer

  • the human mind as an information processing device


The Biological Revolution

  • neurotransmission

  • neuropsychopharmacology

  • human genome→ ~20K genes

  • epigenetics

  • neuroscience

  • neuroimaging techniques (EEG, fMRI, PET, TMS, etc.)


what is science?

  • non-dogmatic→ non-rigid set of beliefs; flexible

  • skeptical → withhold beliefs in truth claims until proven

  • empirical→ relying on evidence

  • cumulative

  • falsifiable→ able to be tested/disproven with evidence


science basics

scientific theories

  • organize and link observed facts

  • imply hypothesis that offer testable predictions

  • falsifiable

the scientific method

  • self-correcting process for asking questions and observing nature’s answers


research designs

Descriptive Studies

  • observational studies→ naturalistic observation

  • watching and recording the behavior of others in their natural environments

  • caveats: no control group, small sample size, hawthorn effect (people change/self-censor once aware they’re being monitored/placed in a public scenario)

  • case studies

  • intensive study of a single individual (ex. Phineas Gage)

  • Phineas Gage

  • tamping iron sent through his left eye out the top of his head

  • frontal lobe damaged

  • he was in a coma, but survived

  • altered behavior→ personality change from nice, agreeable into more impulsive, prone to rage, etc.

  • still physically capable/high functioning otherwise

  • Andrea Yates

  • killed her 5 children via drowning, then dialed 911

  • “heard voices the devil was after her kids, she needed to save them”

  • began showing signs of depression, 2 suicide attempts shortly after birthing her 4th child

  • admitted to psychiatric hospital afterwards→ treated for recurring postpartum depression/psychosis

  • had her 5th child, the mental deterioration came back→ thought of to drive her to murder her kids

  • Caveats to individual cases

  • a data point of n=1 is extremely limited scientific evidence

  • we are our own case studies

  • dramatic/personal experiences can be persuasive, but can often lead to overblown claims or dismissal of scientific findings contrary to personal experiences

  • ex. empirical research→ smokers die younger

  • personal anecdote→ “my uncle smokes 2 packs a day and is still alive at 85”

  • self-report methodology

  • interviews→ structured/unstructured one-on-one questioning

  • questionnaires and surveys are used to gather data from a large number of people in a short time

  • ex. Likert scale (shown below)

  • representative samples

  • if your sample is representative of the population, you can generalize your findings to the entire population


Correlational Research

  • determine an association between 2 variables

  • correlation coefficient (r) → the statistical measure of the relationship between 2 variables

  • can only range from -1→1

    • a positive correlation indicates frequent yoga lessons is accompanied by high energy levels, vice versa, etc.

    • a negative correlation indicates the frequency of the meditation routine is accompanied by less smoking, vice versa, etc.

  • correlation ≠ causation

    • ex. previous studies found watching violent tv is positively correlated with child aggression. does this mean watching these programs causes aggression?

      • 3 possibilities: 1. watching violent tv causes aggression 2. aggressive behavior causes children to watch violent tv 3. a third, unmeasured variable that causes both (third-variable problem)

  • correlation and prediction

  • the more strongly correlated two variables are (positive+negative), the more one variable predicts the other


Experiments

  • experiments detect cause-effect relationships

  • the investigator manipulates one (independent) variable under controlled conditions and observes whether any changes occur in a second (dependent) variable as a result

  • independent variable (IV)

    • presumed “cause”

    • manipulated between control and experimental groups

  • dependent variable (DV)

    • presumed “effect”

    • the outcome of interest measure

Experimental Terms

  • Operational Definition→ need a clear-cut definition of how variables are measured

  • Experimental Group vs. Control Group→ keeping other elements in the experiment consistent vs. sham/sugar pill placebo

  • “Blind” + “Double Blind”→ the participants don’t know which condition is which vs. neither participants nor researchers know which condition is which

  • Random Assignment→ self explanatory; randomly place individuals into whatever group; the great equalizer to control for other variables that may have outside influence

  • Confounding Variables→ specific unknown, outside variables that may influence an experiment’s outcome; want to minimize this


genetics tldr

  • the human body contains trillions of cells→ almost all contain a nucleus containing the genome

  • genomes contain the info needed to build and maintain that organism throughout its life

  • genomes form into human chromosomes (numbered based on size)

  • chromosomes form into DNA, forming into genes

  • ~20k genes in our genome, only ~2% of our entire genome

  • the rest is called non-coding DNA

    • these things can have a variety of functions

    • ex. telomeres→ literally just keeps the chromosomes intact at the end

  • nucleotides/bases:


Genes to Proteins

  • Codon/Tri-nucleotide

    • a sequence of 3 adjacent nucleotides

    • codes for a particular amino acid→ protein building block

  • These amino acids chain together to form a particular protein

  • this depends on the arrangement of tri-nucleotides that make up each gene

  • proteins then direct the biochemical life of the cells that form humans

  • enzyme

    • acts as a “construction worker” within the cell

  • memorize this


mutations

  • gene replication can make mistakes

  • mutations can happen, most generally neutral but can accumulate over a generation→ can be heritable

  • ex. single-letter mistakes


FOXP2 gene + language

  • exclusively human mutation

  • found in all vertebrates, including all mammals/primates

  • humans have a mutation within this that results in a difference of 2 amino acids compared to chimpanzees

  • this variant significantly alters neuron development/functionality in the human brain and motor networks

  • tldr we go from weird noises to actually speaking

  • people with impairments within this gene leads to speech defect

history

  • a family was researched with this language disorder/speech deficiency

  • 1st genetic study traced it to chromosome 7→ “speech 1”

  • an unconnected child with the same defect was brought into the study

  • tests on the new child→ chunks of chromosome 7 was broken off

  • the family had this same issue


huntington’s disease

  • affects motor skills

  • degenerative disease→ fatal

  • huntington’s chorea→ symptom of jerky, involuntary movements

  • caused by a single mutation in a single gene

  • 1 gene has many codons that are like a chain

  • within the huntington gene

    • with ≤ 35 codons→ no huntington’s disease

    • with ≥ 40 codons→ huntington’s disease

    • tldr→ elongated protein chain leads to ill-functioning amino acids/proteins and they kill themselves because they don’t work right (apoptosis)

  • if your parent has huntington’s, you have a 50% chance of developing it

  • it is a dominant trait→ will always be expressed

  • early-onset version is from a large amount of codons (ex. 60+)


genes and environment

  • both genes/environment interact to shape most human psychology and behavior

  • behavior genetics

    • ex.1 studying twins (identical/fraternal)

    • identical twins are more alike in personality/intelligence, etc.

    • ex.2 adoptive children studies

  • heritability

    • the extent of which variations among people within a group are influenced by genes


environments and experience

  • early postnatal experiences can affect brain development

  • ex.

  • not only more activity in certain parts of brain after training, there are changes in brain structure

  • our experiences can alter our DNA

    • telomeres shorten as we age

    • chronic stress accelerates telomere shortening→ accelerated aging

    • enzyme telomerase may heal the telomeres


gene + environment interacions

  • violence/criminal behavior

  • associated with MAO A gene→lack of/low activity + childhood maltreatment= more violent crimes


prenatal development

  • zygote→ fertilized egg with ~100 cells that become increasingly diverse

  • 2 weeks after conception, zygote→ embryo

  • organogenesis→ major organ systems begin to take shape

  • at 9 weeks, embryo→ fetus

  • major organ systems continue to grow/specialize


teratogens

  • chemicals/viruses that can enter the placenta and harm the developing embryo/fetus

  • anything that can make the pregnancy go wrong

prenatal exposure to teratogens

  • fetal alcohol spectrum disorder (fasd)

    • drinking alcohol during pregnancy leads to child born with this

    • associated with small brains, major body/facial deformities, intellectual disability, hyperactivity, seizures


newborns

  • born with reflexes that aid in survival

    • ex. rooting/grasping/crying

  • comforted by touch, rocking/familiar noises

  • comforted from either fear/pain when they are exposed to the odors from their mother’s milk

  • recogize + prefer parents’ voices, and the faces of their caregivers within a few months after birth

temperament

  • a baby’s characteristic emotional reactivity/intensity

  • one way to classify temperament is to assess the degree which children are

    • behaviorally inhibited (shy, fearful, high-reactive)

    • behaviorally uninhibited (bold, positive mood, low-reactive)

    • temperament may change drastically with environmental changes (ex. abuse/bullying)


attachment

  • the emotional bond that forms between newborns and their caregivers

  • harry harlow’s monkey experiments

    • monkeys separated from biological mothers, raised by artificial

    • 1 artificial mother with food, 1 with cloth coating

    • monkeys always preferred the cloth mother even though it had no food

    • harlow showed that infants bond with surrogate mothers because of bodily contact and not nourishment

  • oxytocin levels increase with childhood affection

  • kids raised in orphanages still have lack of oxytocin levels in adulthood, even if adopted into loving families

  • maternal care in rats

    • moms lick their babies as a form of affection

    • low-licking → akin to neglect

    • high-licking→ good for affection, tactile stimulation

    • epigenetic effects, higher brain function/more receptors

    • better responses to stress


attachment theory/attachment styles

  • John Bowlby

    • developed the basic principles of “attachment theory”

    • heavily influenced by Darwin and Harlow

    • attachment is an evolved mechanism that facilitates the survival of helpless offspring

  • Mary Ainsworth

    • developed a classic procedure for classifying different patterns of attachment

    • the strange situation paradigm and attachment styles

      • bring child/parent into laboratory

      • put them in a strange room, observe what happens for a few minutes

      • send in random stranger to sit there a few minutes in, observe

      • mom was told to leave the room a little while later, observe the child

      • mom came back in the room, observe reunion

  • attachment styles

    • secure attachment

      • easily engaged in exploration in caregiver’s presence

      • not unduly wary of stranger

      • under stress, they signal needs

      • actively seek proximity and contact, but tolerates absence

      • comforted by mom when she returns

    • insecure attachment (avoidant)

      • engages in minimal exploration

      • avoids/ignores caregiver

      • does not exhibit distress upon separation

      • caregiver and stranger often treated similarly

    • insecure attachment (anxious-ambivalent)

      • impoverished exploration

      • mere presence not reassuring

      • mixed reactions towards caregiver (ex. sometimes clingy, sometimes angry rejection of caregiver’s comfort)

      • wary of stranger

    • disorganized attachment

      • fear their caregivers

      • prefer the stranger


role of parenting styles

  • parents who exhibit high levels of warmth, support, and concern tend to have children who are more likely to exhibit:

    • secure attachment

    • high self-reliance

    • high social competence

    • high self-esteem

    • low aggression


attachment is based on learned expectations

attachment continues in other relationships

  • from parents to peers→ our close friends become our attachment figures

  • from peers to romantic partner→ our partners become attachment figures

    • we rely on them for comfort in times of need


attachment in romantic relationships

  • secure adult attachment style

    • easy to get close to others

    • happy, friendly, trusting relationships

    • minimal worrying about abandonment

    • more satisfied, committed, intimate

    • more responsive to partner’s needs

  • anxious/ambivalent adult attachment style

    • may have difficulty establishing romantic relationships due to fear of rejection

    • seeks intimacy but worries that partner won’t reciprocate or stay committed

    • more likely to show high levels of jealousy

  • avoidant adult attachment style

    • uncomfortable getting emotionally close to others

    • fear of intimacy and/or committment

    • more likely to have brief sexual encounters

    • use work/sports/etc. to maintain “space”


autism spectrum disorder

  • persistent deficits in social communication and social interaction across multiple contexts

  • parents may notice-

    • avoidance of eye contact

    • difficulty expressing feelings

    • not understanding facial expressions

    • difficulty understanding language subtleties (ex. sarcasm), etc.

  • restricted, repetitive patterns of behavior, interests, or activities

  • parents may notice-

    • preference for routines, and anxiety/anger when a routine is broken

    • unusal rituals/ways of playing with toys

    • repetitive motions, such as rocking/flapping hands

    • saying a word or phrase repeatedly (echolalia)

    • unusual sensory behaviors, etc.

  • diagnosis also specifies-

    • “with or without language impairment” → ~40% are nonverbal

    • “with or without intellectual impairment” → ~35% have impairment

  • symptoms typically recognized between ages 1-4

  • many individuals display “regressive phenotypes”

    • normal development followed by rapid deterioration often before age 2

  • prevalence

    • 1 in 36 births in the US (2.8%)

  • sex differences

    • 3-4x more common among boys than girls

  • comorbidity with epilepsy, anxiety/mood disorders, adhd, gastrointestional issues (ex. ARFID)

  • asperger’s is no longer an official diagnosis in DSM-5

    • now diagnosed as “autism spectrum disorder without language/intellectual impairment”

  • ~400 genes shown to be associated with autism

    • most genes involved with protein synthesis for synaptic function in the brain

    • risk for the majority of cases are polygenic (possibly hundreds of genetic loci making relatively small contributions)

  • other risk factors

    • prenatal exposure to fever

    • maternal metabolic conditions (ex. diabetes, obesity) during pregnancy

    • lack of maternal folic acid intake during pregnancy

    • increased parental age

    • having an older sibling with autism

  • autism is not a degenerative disorder

    • developmental gains typical in later childhood in at least some areas

  • many people with autism report “masking” in public social situations, can find a niche that matches special interests/skills, etc.


cognitive development

  • jean piaget

    • studied errors in cognition made by children to understand in what ways they think differently than adults

    • considered the father of modern developmental psychology

piagetian terminology

  • schema

    • concept or framework that organizes and interprets information

  • assimilation

    • interpreting new experiences in terms of existing schema

  • accommodation

    • adapting current schemas to incorporate new information


piaget’s stage 1

sensorimotor (birth-2 years)

  • infants acquire information about the world by sensing it and moving around within it

  • object permanence

    • the idea that objects continue to exist even when not visible

    • emerges around 8 months

  • able to recognize themselves in a mirror closer to ~1 1/2 years


piaget’s stage 2

preoperational (2-7 years)

  • have basic understanding of the physical world

  • use visual models to represent other places and perform pretend play

  • display egocentric thinking at the beginning of this stage

  • theory of mind

    • awareness that other people have minds of their own and they may hold different feelings/thoughts/perceptions than our own

    • develops around age 4


piaget’s stage 3

concrete operational (7-12 years)

  • children can think logically about concrete events, grasp concrete analogies and perform arithmetic operations

  • grasp the concept of conservation

    • ex. mass/volume/number of things may remain the same despite changes in the forms of objects→ same amount of water in different shaped glasses


piaget’s stage 4

formal operational (12-adulthood)

  • individuals can now think logically about abstract concepts

  • the emergence of hypothetical thinking

    • capability of solving hypothetical problems and deducing consequences

  • moral reasoning becomes more sophisticated


neurons and neurotransmission

basic structure of a neuron

dendrites

  • receive incoming information

axon

  • the sending end of neurons


types of neurons

  • sensory neurons

    • body→ nervous system

  • motor neurons

    • nervous system→ body

  • interneurons

    • local connectors within spinal cord + brain

  • mirror neurons

    • helps us to process our own and other peoples’ emotions/behaviors


how do neurons work?

resting potential

  • difference in electrical charge (voltage) between the inside/outside of the neuron at rest

  • electrical voltage inside is -70mV→ hyperpolarized state

  • high concentration of sodium ions (Na+) outside neutron

  • high concentration of potassium ions (K) inside neutron

action potential

  • a brief reversal of electron polarization of the nuron


sodium/potassium pump

  • na+ concentration is higher inside the cell immediately after action potential

  • k+ concentration is lower inside cell immediately after action potential

  • a mechanism called the Na+/K+ pump restores ion balance and reestablishes resting potential


propagation of the action potential

  • action potential gets sent (propagated) down the axon

    • wave of sodium (Na+) entry

    • wave of potassium (K+) exit

  • the speed of electrical conductance depends on whether the axon has a myelin sheath

    • no myelin= continuous conduction (baby steps, slow)

    • myelinated= saltatory conduction (faster process)


gray matter

  • somas and dendrites

white matter

  • myelinated axons and glial cells


synapse and neurotransmitters

  • synapse

    • short range chemical messengers

    • gap between neurons

  • neurotransmitters get dumped into the synapse when the action potential reaches the axon terminal, then attach to receptor proteins on the receiving neuron’s dendrites

  • specific neurotransmitters bind to specific receptor sites like keys→ lock

  • synaptic vesicles

    • contain chemical messages (neurotransmitters)

    • end of the axon


excitatory and inhibitory neurotransmitters

  • transmission across the synapse does not necessarily result in an action potential

  • excitatory neurotransmitters

    • depolarize the post-synaptic membrane

    • increased likelihood of action potential

  • inhibitory neurotransmitters

    • hyperpolarize the post-synaptic membrane

    • decreased likelihood of action potential

  • all communications are added together

  • with enough excitation, the receiving neuron will produce an action potential in an “all or none” fashion


terminating synaptic transmission

  • reuptake

    • “vacuuming” back molecules to recycle/reuse

    • ex. antidepressants (SSRIs) block the reuptake

  • enzyme deactivation

    • releasing enzymes that attach to neurotransmitters and rip them apart, then put them back together


common neurotransmitters

  • acetylcholine (ACh)

    • released by motor neurons controlling skeletal muscles

    • always involved in muscle activity

    • regulation of attention, arousal, memory

    • some receptors stimulated by nicotine

  • dopamine (DA)

    • contributes to control of voluntary movement

    • cocaine/amphetamines elevate activity at DA synapses

    • dopamine circuits in medial forebrain bundle

    • tldr→ reward pathway

  • norepinephrine (NE)

    • mood/arousal modulation

    • cocaine/amphetamines elevate activity at NE synapses

  • serotonin

    • sleep/wakefulness regulation, eating, aggression

    • prozac and similar antidepressant drugs affect serotonin circuits

  • GABA

    • serves as widely distributed inhibitory transmitter

    • anxiety and sleep/arousal regulation

    • valium and similar antianxiety drugs work at GABA synapses

  • glutamate

    • serves as widely distributed excitatory transmitter

    • involved in learning/memory

  • endorphins

    • natural steroids

    • resemble opiate drugs in structure/effects

    • pain relief/stress response

    • contributes to regulation of eating behavior