medication administration

Medication Administration Overview

Terminology

  • MAR: Medication Administration Record

  • EMAR: Electronic Medication Administration Record

  • Bar Code Administration: A process using barcodes to track medications to enhance safety in medication administration.

  • Chemical Name: The scientific name that describes the chemical composition and molecular structure of a drug.

  • Generic Name: The non-proprietary name of a drug that is universally accepted.

  • Trade Name: The brand name under which the drug is marketed.

Classifications

  • Medications: Classified based on:   - Method of Action Against Diseases: Classified by their pharmacological effect on bodily systems.   - Chemical Composition: Grouped based on chemical properties.   - Clinical Indications: Based on the therapeutic effects intended by the clinical use.   - Therapeutic Classification: Describes the therapeutic target of the medication.   - Pharmacologic Classification: Groups medications based on their mechanism of action, with similar indications, precautions, and nursing implications.

Medication Actions

  • Therapeutic Effect: The intended beneficial effect of a medication.

  • Side Effects: Undesired effects that typically occur alongside therapeutic effects.

  • Tolerance: Reduced effectiveness of a drug due to prolonged use, requiring increased dosages to achieve the original effect.

  • Toxicity: The degree to which a substance can damage an organism; harmful effects on health.

  • Idiosyncratic Effect: An abnormal or unexpected response to a drug, unique to an individual.

  • Severe Adverse Effect: A serious unintended reaction to a drug that may require discontinuation or special management.

  • Allergic Reaction: An immune system response to a substance that may be harmful or life-threatening.

  • Anaphylactic Reaction: A severe, potentially life-threatening allergic reaction that requires immediate medical intervention.

Adverse Effects
  • Synergy/Synergism: Enhanced effect when two drugs are used together compared to the action of each drug alone.

  • Antagonists/Antagonism: When one drug reduces or counteracts the effect of another drug.

  • Incompatibility: A condition where two substances, when mixed, do not combine well and can produce undesired effects.

  • Teratogenic Effects: Drugs that can cause developmental anomalies in a fetus when taken during pregnancy.

Medication Dose Response Terms

  • Onset: Time taken for the medication to take effect after administration.

  • Duration: The length of time the medication remains effective in the body.

  • Peak: The time at which the drug concentration is at its highest and the effect is greatest.

  • Trough: The lowest concentration of a drug in the bloodstream before the next dose is administered.

  • Plateau: The stable level of drug concentration in the bloodstream after repeated dosing.

  • Plasma Concentration: The amount of drug present in the plasma at a given time.

  • MEC (Minimum Effective Concentration): The lowest concentration at which a drug produces its desired therapeutic effect.

  • Therapeutic Window: The range between the MEC for a desired response and the MEC for an adverse response.

  • Half-Life: The time taken for the plasma concentration of a drug to reduce to half its initial value.

  • Lag Period: The delay before the drug starts to exert its pharmacological effect.

  • Therapeutic Range: The concentration range in which a drug is effective without being toxic.

Medication Orders

  • Types of Orders:   - Routine Order: A standing order implemented until canceled.   - Standing Order: Medication orders administered continuously until specified conditions are met.   - PRN (Pro Re Nata): Medications given as needed based on specific parameters.   - BTP (Breakthrough Pain): Medications administered for sudden, intense episodes of pain.   - Single Order: A one-time medication order.   - Stat: An order for immediate administration of a medication.

  • Telephone or Verbal Orders: Orders received orally that should be documented carefully to ensure accuracy.

  • Medication Reconciliation: The process of comparing medications the patient is currently taking with new medications ordered to prevent errors.

Medication Administration Essentials

  • Triple Check Process:   - First Check: Verification when reaching for the medication.   - Second Check: Verification of the dose while holding the medication.   - Third Check: Final verification before administration.

  • Three Checks (distinct from the triple check):   - Verify the medication order.   - Check patient's allergies.   - Confirm medication expiration date.

Six Rights of Medication Administration
  1. Right Drug: Verify the correct medication is being administered.

  2. Right Dose: Confirm the correct dosage as prescribed.

  3. Right Route: Ensure the medication is given via the correct route (e.g., oral, IV).

  4. Right Time: Administer the medication at the correct time intervals.

  5. Right Patient: Verify the identity of the patient receiving the medication.

  6. Right Documentation: Accurately document all medication administration and responses.

Routes of Medication Administration

  • Sublingual (SL): Under the tongue.

  • Buccal: Between the gum and cheek.

  • Enteral (FT): Via the gastrointestinal tract.

  • Inhalation: Sprayed into the respiratory tract.

  • Topical: Applied directly to the skin.

  • Transdermal (TD): Medication absorbed through the skin via patches.

  • Ophthalmic: For use in the eyes.

  • Otic: For use in the ears.

  • Nasal: Administered in the nostrils.

  • Rectal: Inserted into the rectum.

  • Vaginal: Inserted into the vagina.

  • Parenteral: Administered via injection or infusion, bypassing the gastrointestinal tract:   - Subcutaneous: Injected into the tissue layer between the skin and muscle.   - Intramuscular (IM): Injected deep into a muscle.   - Intravenous (IV): Administered directly into the bloodstream.   - Epidural: Injected into the epidural space of the spinal cord.   - Intrathecal: Injected into the spinal canal.

Patient’s Rights in Medication Administration (Ethical Considerations)

  1. Right to Information: Patients should be informed about their medications and treatment options.

  2. Right to Refuse: Patients have the right to refuse any medications.

  3. Right to Careful Assessment: Patients are entitled to a meticulous evaluation before medication administration.

  4. Right to Informed Consent: Patients should consent to treatment with a full understanding of the implications.

  5. Right to Safe Administration: Assurance that medications are administered safely and correctly.

  6. Right to Supportive Therapy: Patients should receive assistance for symptom management and care.

  7. Right to No Unnecessary Medications: Avoid administering medications that are not medically necessary.

Pre-Administration Assessment

  • Comprehensive evaluation involving:   - Medication History: Past and current medication use.   - Allergies: Documented allergic reactions to previous medications.   - Current Medication List: Review to avoid drug interactions.   - Diet History/Diet Order: Consider dietary factors that may affect medication absorption.   - Neurological Problems: Assess neurological function as needed for medication action.   - Current Condition: Evaluate the patient’s presenting condition for appropriateness of prescribed medications.   - Lab Values: Relevant laboratory results that affect medication choices.   - Physical Assessment: Thorough examination of the patient’s overall physical condition.

Evaluation

  • Timing: When to evaluate medication effectiveness and safety.   - Determine Therapeutic Effect: Assess whether the medication is providing the desired outcome.   - Determine Adverse Effects: Monitor for any negative side effects generated by the medication.

Special Considerations in Medication Administration

  • Polypharmacy: The concurrent use of multiple medications which increases the risk of adverse effects.

  • Misuse: Incorrect or improper use of medications.

  • Non-adherence/Non-compliance: Patients failing to take medications as prescribed.

  • Vitamins, Supplements, and Over The Counter (OTC) Medications: Potential interactions with prescribed medications must be considered.

  • Age-related Considerations: Adjustments may need to be made for pediatric and geriatric patients due to differing pharmacokinetics and dynamics.

General Administration Principles

  • Medications should remain in their individual dose packaging until just before administration.

  • Only the professional who prepared the medication should administer it.

  • Medications must not be left unattended to avoid unauthorized access or errors.

  • Medication Security: Proper protocols to protect and manage medications securely.

  • Verification of administration must be strict.

  • Unused medications should be disposed of according to established regulations.

  • Medications can be withheld based on clinical assessments and in collaboration with the physician.

Controlled Substances
  • Regulated by Federal Law: Stricter laws govern the prescription, dispensing, and administration of controlled substances.

  • Who Can Prescribe?: Only licensed professionals under specific regulations can prescribe controlled substances.

  • Specific Record Keeping: Detailed documentation required for all transactions involving controlled substances.

  • Procedures: Guidelines for dispensing and wasting controlled substances must be followed meticulously.

Medication Errors

  • Incidence of Medication Errors: Approximately 1.5 million medication errors that lead to harm are reported annually.

  • Phases Where Errors Occur:   - Ordering: Errors in the prescribing phase may occur due to illegibility or misunderstanding.   - Transcribing: Poorly documented orders can lead to incorrect medications being administered.   - Dispensing: Mistakes during the preparation and delivery of medications to patients.   - Administering: Errors made during the final phase of giving medications to patients.

  • Causes of Errors: Can result from human factors or inadequate systems in medication management.

Factors Leading to Administration-Related Medication Errors

  1. Complexity of Medication Regimens: Multi-drug treatments can lead to confusion and mistakes.

  2. Lack of Staff Training or Experience: Insufficient knowledge and skills can contribute to errors.

  3. Poor Communication: Between healthcare staff regarding medication orders or changes.

  4. Insufficient Time: Rushing due to heavy workloads can lead to oversight.

  5. Inadequate Documentation: Missing or incomplete records can impact administration.

Processes and Systems to Reduce Errors

  • TallMAN Letters: Use of mixed-case letters to enhance the differentiation of drug names that are often confused.

  • High Alert Medications: Identification and management of drugs that have a higher risk of causing harm if misapplied.

  • Dual Verification: Involvement of two qualified professionals in verifying medication orders or administration to minimize errors.