The Cranial Nerves

Overview of Cranial Nerves

  • There are 12 pairs of cranial nerves.

  • These nerves innervate the periphery and emerge directly from the brain (not from the spinal cord).

  • The cranial nerves are located on the ventrolateral surface of the brain.

  • They are numbered starting from the anterior aspect of the brain as follows:

    • CN I to CN XII


Mnemonic Devices for Cranial Nerves

Various Mnemonics for Remembering Cranial Nerves:
  1. Orange Oregon O-lineman Tried Track And Field, Victory Gave Virginia School Honor

  2. On Occasion Our Trusty Truck Acts Funny, Very Good Vehicle Any How

  3. Once One Openly Told Tourists About Fighting Vampires Gobling Various Antelope Herds

  4. On Old Olympus' Towering Top, A Friendly Viking Grew Vines And Hops

  5. Oh Once One Takes The Anatomy Final Very Good Vacations Are Heavenly.

  6. Oh, Oh, Oh, To Touch And Feel Very Good' Velvet Aah Hah

  7. Oh, Oh, Oh, To Touch And Feel Very Good Vibes AHhhh

  8. One Of Old Trained Teacher Ask For A Girl Vadai And Halva

  9. Oh, Oh, Oh, To Touch And Fondle A Gorgeous Very Super Human

  10. Oh, Oh, Oh, To Touch And Feel Very Green Vegetables, Such Heaven

  11. Oh, Oh, Oh, To Take A Family Vacation! Go Vegas After Hours

  12. Only Owls Observe Them Traveling And Finding Voldemort Guarding Very Secret Horcruxes

  13. Old Opie Occasionally Tries Trigonometry And Feels Very Gloomy, Vague And Hypoactive

  14. Old Oprah Occasionally Trots Triumphantly About, Farting Velveeta Globs, Vaunting Accolades Hysterically

  15. Oh, Oh, Oh, To Touch And Feel Vintage Green Velvet, Simply Heaven

  16. Old, Oliver, Ogg, Traveled, To, Africa, For, Very, Good, Vacations, And, Holidays

  17. Once On October Thirteenth, Troublesome Abductors Filched Various Golden Valuables And Heirlooms

  18. Oprah Ought Order Tasty Treats And Finally Value Growing Voluptuous And Happy

  19. Old Officers Often Trust The Army For A Glory Vague And Hypothetical

  20. Old Oppressive Oceanic Trout Trick Aquatic Fauna Very Greedily; Valiant Sharks Hunt (them).


Detailed List of Cranial Nerves

CN I: Olfactory Nerve
  • Function: Sensory (smell)

  • Origin: Olfactory epithelium

  • Foramen: Olfactory foramina

  • Destination: Olfactory bulbs


CN II: Optic Nerve
  • Function: Sensory (vision)

  • Origin: Retina

  • Foramen: Optic canal

  • Destination: Diencephalon, then to occipital lobe


CN III: Oculomotor Nerve
  • Function: Controls extra-ocular eye muscles (motor function)

    • Muscles controlled: Superior, inferior, medial rectus, inferior oblique

    • Levator palpebrae superioris

  • Origin: Mesencephalon

  • Foramen: Superior orbital fissure

  • Destination: Extra-ocular eye muscles


CN IV: Trochlear Nerve
  • Function: Controls the superior oblique muscle (motor function)

  • Origin: Mesencephalon

  • Foramen: Superior orbital fissure

  • Destination: Superior oblique muscle


CN V: Trigeminal Nerve
  • Function: Mixed (sensory and motor)

    • Sensory: Touch, pain, temperature, vibration from the anterior 2/3rds of the tongue.

    • Ophthalmic: Sensations from forehead, eyelids, and nose.

    • Maxillary: Sensations from lower eyelid, upper lip, and cheek.

    • Mandibular: Controls mastication.

  • Origin: Ophthalmic, maxillary, and mandibular nerves

  • Foramina:

    • Ophthalmic: Superior orbital fissure

    • Maxillary: Foramen rotundum

    • Mandibular: Foramen ovale

  • Destination:

    • Ophthalmic and maxillary: Pons

    • Mandibular: Mandibular muscles


CN VI: Abducens Nerve
  • Function: Controls eye movements (motor function)

  • Origin: Pons

  • Foramen: Superior orbital fissure

  • Destination: Innervates the lateral rectus muscle


CN VII: Facial Nerve
  • Function: Mixed (sensory and motor)

    • Sensory: Taste from anterior 2/3rds of tongue.

    • Motor: Muscles of facial expression

  • Origin: Sensory from taste buds, motor from pons

  • Foramen: Internal acoustic meatus to the stylomastoid foramen

  • Destination: Sensory to pons, motor to muscles of the face, lacrimal gland, parasympathetic to submandibular and sublingual salivary glands


CN VIII: Vestibulocochlear Nerve
  • Function: Sensory (balance and hearing)

  • Origin: Receptors of the vestibule and cochlea

  • Foramen: Internal acoustic meatus

  • Destination: Pons


CN IX: Glossopharyngeal Nerve
  • Function: Mixed (sensory and motor)

    • Sensory function: Tongue pain from posterior 1/3 of the tongue.

    • Motor function: Swallowing

  • Origin: Sensory from posterior 1/3 of the tongue, motor from the parotid gland and parasympathetic to salivary gland

  • Foramen: Jugular foramen

  • Destination: Sensory to medulla oblongata, visceral motor to the parotid salivary gland, somatic motor to pharyngeal muscles for swallowing


CN X: Vagus Nerve
  • Function: Mixed (sensory and motor)

    • Sensory: Information from organs

    • Motor: Sends information to organs

  • Origin: Sensory from the organs, motor from medulla oblongata

  • Foramen: Jugular foramen

  • Destination: Sensory to the autonomic centers of the medulla oblongata, somatic motor to muscles of the palate and pharynx, visceral motor to respiratory, cardiovascular, and digestive organs


CN XI: Accessory Nerve
  • Function: Motor function controlling the sternocleidomastoid, trapezius, palate, pharynx, and larynx muscles

  • Origin: Spinal cord and medulla oblongata

  • Foramen: Jugular foramen

  • Destination: Internal branch to muscles of the palate, pharynx, larynx; external branch to sternocleidomastoid and trapezius muscles


CN XII: Hypoglossal Nerve
  • Function: Motor, controls tongue movement

  • Origin: Medulla oblongata

  • Foramen: Hypoglossal canal

  • Destination: Tongue muscles


Summary of Cranial Nerve Functions

Cranial Nerve

Primary Function

Source

Foramen

Destination

CN I: Olfactory

Sensory (smell)

Olfactory epithelium

Olfactory foramina

Olfactory bulbs

CN II: Optic

Sensory (vision)

Retina

Optic canal

Diencephalon, occipital lobe

CN III: Oculomotor

Motor

Mesencephalon

Superior orbital fissure

Extra-ocular muscles

CN IV: Trochlear

Motor

Mesencephalon

Superior orbital fissure

Superior oblique muscle

CN V: Trigeminal

Mixed

Various

Various

Pons, mandibular muscles

CN VI: Abducens

Motor

Pons

Superior orbital fissure

Lateral rectus muscle

CN VII: Facial

Mixed

Taste buds, Pons

Internal acoustic meatus

Muscles of face, lacrimal & salivary glands

CN VIII: Vestibulocochlear

Sensory

Receptors of vestibule & cochlea

Internal acoustic meatus

Pons

CN IX: Glossopharyngeal

Mixed

Posterior 1/3 of tongue

Jugular foramen

Medulla oblongata, pharyngeal muscles

CN X: Vagus

Mixed

Organs

Jugular foramen

Various organs

CN XI: Accessory

Motor

Spinal cord & medulla

Jugular foramen

Palate, pharynx, larynx secondaires

CN XII: Hypoglossal

Motor

Medulla oblongata

Hypoglossal canal

Tongue muscles


Cranial Reflexes

Table 16.13: Reflexes Related to Cranial Nerves

Reflex

Stimulus

Afferents

Central Synapse

Efferents

Response

Corneal Reflex

Contact with corneal surface

NV

Motor nuclei for N VII

N VII

Blinking of eyelids

Tympanic Reflex

Loud noise

N VIII

Inferior colliculi (midbrain)

N VII

Auditory reflexes

Vestbulo-ocular Reflexes

Rotation of head

N VIII

Motor nuclei controlling extra-ocular muscles

N III, IV, VI, VII, X, cervical nerves

Opposite movement of eyes to stabilize field of vision

Direct Light Reflex

Light striking photoreceptors

N II

Superior colliculi

N III

Constriction of ipsilateral pupil

Consensual Light Reflex

Light striking photoreceptors

N II

Superior colliculi

N III

Constriction of contralateral pupil