Bone Tissue: Cells, Structure, and Remodeling

Bone Cells and Microscopic Structure

  • Osteocytes: These are mature bone cells. The term osteo refers to bone, and cytes refers to cells. They are given this name if they build the extracellular matrix. Because bone's extracellular matrix is rigid, these cells reside in lacunae (small cavities) within the matrix.
    • Canaliculi: These are long, thin, hollow pathways through the bone that allow the cellular processes (extensions) of osteocytes to extend. This arrangement allows osteocytes to be in close proximity, essentially "fingertip to fingertip" with each other.
    • Gap Junctions: Located at the ends of these cellular processes within the canaliculi, gap junctions facilitate communication between osteocytes.
  • Osteoblasts: These cells are responsible for depositing new bone tissue. They lay down bone extracellular matrix, which is crucial for building more bone.
  • Osteoclasts: These cells are responsible for breaking down (resorbing) bone tissue. They play a vital role in remodeling and calcium release.
  • Osteons: These are the fundamental units of compact bone, providing its weight-bearing capacity. They are organized to resist compression, making compact bone very strong and capable of carrying the body's weight.