clathrin indepent endocyrosis

Non-Receptor Mediated Endocytosis

• Pinocytosis is an example of non-receptor mediated endocytosis.

• The solute and fluid present during vesicle formation are what end up inside the vesicle.

• There is no concentration of specific substances like in receptor-mediated endocytosis where receptors and ligands are involved.

• Occurs at a constant rate.

Compensation for Exocytosis

• Helps to compensate for exocytosis.

• Exocytosis adds membrane to the cell membrane.

• Endocytosis removes parts of the membrane to maintain a constant cell membrane size.

• Exocytosis and endocytosis balance each other out.

• Maintains a constant size to the cell membrane.

• Controls the cell's volume to surface area ratio.

Vesicle Routing and Coding

• Vesicles coming in through endocytosis are routed to early endosomes, similar to what was shown previously.

• Most vesicles have a protein coding.

• Receptor-mediated endocytosis is the primary way this occurs.

Importance of Coding Type

• Due to that importance, the type of coding used is important.

• It indicates the origin and destination of the vesicle.

• Endocytosis at the plasma membrane uses a different coded protein than endocytosis at the Golgi.