Chapter 2- Genetics

Slipped mispairing
Trinucleotide repeats
Anticipation
Mutagen
Deamination
Depurination
Mismatch repair
Nucleotide excision repair
NHEJ
Homologous recombination
Missense
Nonsense
Silent
Frameshift
Null mutation
Temperature sensitivity
Lethal mutation
“Essential” gene
Haploinsufficient
Transposable element/transposon
Transposition
Dominant-negative
Single nucleotide polymorphism
Genetic polymorphism
Wildtype
Fidelity (referring to DNA polymerase)
Exonuclease site
“Proof-reading”
Hypermorph
Neomorph
Germ cell
Germline mutation
Somatic cell
Somatic mutation
Homologous chromosome
Allele
Sister chromatid
Quiescence
Interphase
G1, S, G2, M phases
Mitosis
Meiosis
Cytokinesis
Bivalent/tetrad
Metaphase plate

Ploidy
Haploid
Diploid
Polyploid
Karyotype
Autosome
Sex Chromosome
Centromere
Mitotic spindle
Prophase
Metaphase
Anaphase
Telophase
Centromere
Synapsis
Chiasma (plural chiasmata)
Crossing over
Homologous recombination
Zygote
Spermatogenesis
Oogenesis
Bipolar attachment
Nondisjunction
Aneuploidy
Trisomy
Monosomy
necessary (as it’s used in genetics)
sufficient (as it’s used in genetics)
“cis” function
SRY gene
pseudoautosomal region
Xist
Barr body