Neurotransmitters
Adrenaline (Fight or Flight): Produced in stressful situations. Increases heart rate and blood flow. Leading to physical boost and heightened awareness
Gaba (Calming): Calming firing nerves in the central nervous system high levels improve focus and low levels cause anxiety. Also contributes to motor control and vision
Noradrenaline (Concentration): affects attention and responding actions in the brain. Contracts blood vessels increasing blood flow
Acetylcholine (Learning): Involved in thought. Learning and memory. Activates muscle action in the body. Also associated with attention and awakening.
Dopamine (Pleasure): feelings of pleasure, also addiction, movement and motivation. People repeat behaviours that lead to dopamine release
Glutamate (Memory): Most common neurotransmitter. Involved in learning and memory. Regulates development and creation of never contacts
Serotonin (Mood): Contributes to well-being and happiness helps sleep cycle and digestive system regulation. Affected by exercise and light exposure
Endorphins (Euphoria): Released during exercise. Excitement and sex produce well-being and euphoria. Reducing pain
Second messenger: a chemical that, when activated by a neurotransmitter, initiates communication to many areas within the neuron
How do Metabotropic receptors: When a neurotransmitter binds, instead of a ion channel opening, this then activates the G protein, to either open a neighboring ion channel or invites a second messenger
Most excitatory ionotropic synapses Use which neurotransmitter: Glutamate. Opens NA+
Ionotropic receptor: When a neurotransmitter binds to the receptor it opens up allowing for one type of ion to pass through
How do we synthesis neurotransmitters: Our neurons create these neurotransmitters and other chemicals through the foods that we eat.
Neurotransmitter: act quickly and locally to send specific signals between neurons at synapses
Nueromodulators: Modulate the activity of neurons and neural circuits over time periods and often across wider regions of the brain
In order for a molecule to be classified as a neurotransmitter it must: Chemicals produced within a neuron
In order for a molecule to be classified as a neurotransmitter it must: Released by a neuron following depolarization from presynaptic neuron and acts on adjacent post-synaptic neuron
In order for a molecule to be classified as a neurotransmitter it must: Exogenous administration mimics endogenous release (drugs!)
In order for a molecule to be classified as a neurotransmitter it must: Does not remain in the postsynaptic cleft for a long period (clearance)