M2L7 Tertiary lymphoid structures in cancer

IgM is the first antibody to appear in the primary immune response, followed by IgG

In secondary response, IgG appears earlier than IgM and its final concentration is higher than in primary response

• There is also increased conc of IgA and IgE

Lymph nodes - groups of small bean-shaped organs found mainly in necka nd trunk of human body, playing vital roles in filtering antigens and debris

• Hubs to mount humoural response

Activated B cells —> centroblast —> centrocyte