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Overview of the Nervous System

  • Central Nervous System (CNS) consists of the brain and spinal cord.

  • Peripheral Nervous System (PNS) connects the body to the CNS.

    • Divided into motor nerves (efferent) and sensory nerves (afferent).

Functions of the Nervous System

  • Three overlapping functions:

    1. Sensory Input: Receptors detect changes (stimuli) in the environment inside or outside the body.

    2. Integration: CNS processes and interprets sensory input.

    3. Motor Output: CNS signals organs/muscles to elicit a response.

Nervous Tissue Components

  • Two main cell types in nervous tissue:

    1. Neurons: Transmit electrical signals (action potentials).

    2. Neuroglial Cells: Support, protect, and nourish neurons.

Types of Neurons

  • Multipolar Neurons: Many dendrites, one axon (common).

  • Bipolar Neurons: Two processes (rare, involved in special senses).

  • Unipolar Neurons: One process (mostly sensory neurons).

Synapse and Signal Transmission

  • Synapse: Junction between two neurons for signaling.

  • Neurotransmitters: Chemicals released across synaptic cleft.

Gray and White Matter

  • Gray Matter: Composed of neuron cell bodies, dendrites, and non-myelinated axons (CNS).

  • White Matter: Composed of myelinated axons (CNS), facilitating rapid signal transmission.

Neuroglial Cells Types

  • CNS: Astrocytes, Microglia, Ependymal Cells, Oligodendrocytes.

  • PNS: Satellite Cells, Schwann Cells (produce myelin).

Regeneration and Injury

  • PNS: Axons can regenerate through Schwann cells creating a regeneration tube.

  • CNS: Damage to cell bodies is typically irreversible.

Disorders of the Nervous System

  • Multiple Sclerosis (MS): Autoimmune disease attacking CNS myelin, causing symptoms like numbness and paralysis.

Development of the Nervous System

  • Develops from ectoderm, forming a neural tube (becomes spinal cord) and neural crest (forms sensory neurons).