Med-Surg GI: Drug Indications & Variceal Bleeding

H2 Receptor Antagonist

  • Famotidine
    • Indication: treatment of stress ulcers.

Proton Pump Inhibitors (PPIs)

  • Esomeprazole
    • Indication: management of gastroesophageal reflux disease (GERD).
  • Omeprazole
    • Indication: treatment of duodenal and gastric ulcers.

Vasoactive Agent

  • Vasopressin
    • Mechanism: constricts the splanchnic circulation and peripheral veins → \downarrow portal venous inflow and pressure.
    • Primary use: control of bleeding esophageal varices.