Buffers Notes

Buffers

Definition

  • Solutions containing a weak conjugate acid-base pair.

  • Resist changes in pH upon addition of small amounts of strong acid or base.

  • Important in lab work and biological systems (e.g., blood).

Mechanism

  • Based on Le Chatelier's principle.

  • If you add hydroxide, acetic acid will react with water to replace the hydronium ions used up.

  • If you add hydronium ions, it will react with the acetate ions to use up the excess hydronium added.

Buffer Capacity

  • Limited capacity to maintain constant pH.

  • Depends on significant amounts of weak acid-base pair.

  • Compromised when concentrations of buffer pair members are lowered by added acid or base.

  • Increasing the concentration of the weak acid or base and its conjugate pair can increase the buffer capacity, while maintaining it's ratio.

  • Changing the ratio changes the pH maintained by the buffer.

Selection Criteria

  • Good buffers have about equal concentrations of both components.

  • Weak acids/salts are better for pH < 7; weak bases/salts for pH > 7.

  • A buffer loses effectiveness when one component is < 10% of the other.

Henderson-Hasselbalch Equation

  • Useful for dealing with buffers.

  • pH=pKa+log([salt]/[acid])pH = pKa + log([salt]/[acid])

  • pH=pKa+log([conjugate base]/[acid])pH = pKa + log([conjugate \ base]/[acid])

  • Important to note that the 'x is small' assumption must be valid to use this equation.