Mod 6

SKELETAL SYSTEM

Module 6: Skeletal Chapter 13

Points to Ponder
  • What are the 5 functions of the skeletal system?

  • What is compact bone? Spongy bone?

  • How are bones classified?

  • What are the parts of a long bone?

  • What are the differences between red and yellow marrow?

Functions of the Skeletal System
  1. Support: Provides structural support for the body, primarily through the legs and pelvic girdle.

  2. Protection: Protects soft body parts:

    • Skull protects the brain.

    • Ribcage protects the heart and lungs.

    • Vertebrae protect the spinal cord.

  3. Produces Blood Cells: Blood cells are produced by stem cells located in red bone marrow.

  4. Stores Minerals and Fat: Stores vital minerals such as calcium and phosphate, as well as fat.

  5. Movement: Facilitates movement by providing attachment points for muscles.

Types of Bone
  • Compact Bone:

    • Composed of osteons, which possess a central canal containing blood vessels.

    • Contains living bone cells, termed osteocytes.

    • Features chambers known as lacunae.

    • Yellow marrow is located in the medullary cavity.

    • Primarily found in the diaphysis (middle portion) of long bones.

    • Provides protection, support, and resistance to external stresses.

  • Spongy Bone:

    • Comprised of plates of bone known as trabeculae, filled with red bone marrow.

    • Displays a disorganized and irregular arrangement of osteocytes.

    • Lighter in weight compared to compact bone.

    • Red bone marrow is found within the spaces of spongy bone.

    • Located primarily in the epiphysis (ends) of long bones, and in areas of growth plates.

Classification of Bones
  • Long Bones: Example: Femur

  • Short Bones: Example: Carpals

  • Flat Bones: Example: Parietal Bone

  • Irregular Bones: Example: Vertebrae

  • Sesamoid Bones: Example: Patella

Bone Cells
  • Osteoblasts: Bone-forming cells that are responsible for new bone development.

  • Osteocytes: Mature bone cells derived from osteoblasts that help maintain bone structure.

  • Osteoclasts: Bone-absorbing cells that are responsible for breaking down bone tissue.

Anatomy of a Long Bone
  • Diaphysis:

    • The shaft of the bone composed of compact bone and filled with yellow marrow.

  • Epiphysis:

    • The ends of the bone primarily made up of spongy bone.

  • Articular Cartilage:

    • Hyaline cartilage located at the ends of long bones that reduces friction in joints.

  • Yellow Bone Marrow:

    • Functions primarily in fat storage and is found in the medullary cavity.

  • Red Bone Marrow:

    • Responsible for blood cell production, found in spongy bone and some flat bones.

  • Periosteum:

    • A fibrous connective tissue layer that covers the outer surface of the bone, containing nerves and blood vessels.

  • Ligaments:

    • Fibrous connective tissue that connects bones at joints.

Osteoporosis
  • Definition: A condition characterized by decreased bone mass, leading to fragile bones.

  • Pathophysiology: Occurs when bone reabsorption exceeds bone formation, typically starting around age 40.

  • Risk Factors:

    • Gender: Females are at higher risk.

    • Ethnicity: Higher prevalence in White or Asian individuals.

    • Body type: Thin individuals are more susceptible.

    • Family history: Genetic predisposition.

    • Age: Early menopause can increase risk.

    • Lifestyle: Smoking, low calcium intake, excessive caffeine or alcohol consumption, and a sedentary lifestyle contribute.

  • Complications: Increased risk of fractures and other related complications.

  • Treatment: Management can include drugs, hormonal therapies, and lifestyle modifications.

MUSCULAR SYSTEM

Module 6: Chapter 14

Points to Ponder
  • What are the 3 types of muscle tissue?

  • What are the functions of the muscular system?

  • What terms are used to describe muscle movements?

  • How do skeletal muscle cells acquire ATP for contraction?

  • What are some serious muscle diseases?

  • How do the skeletal and muscular systems help maintain homeostasis?

Types of Muscle Tissue
  • Skeletal Muscle:

    • Appearance: Long, parallel cells (fibers) that are multinucleated and striated.

    • Location: Attached to bones or skin.

    • Control: Voluntary control via the somatic nervous system.

  • Cardiac Muscle:

    • Appearance: Branched cells connected by intercalated discs containing desmosomes and gap junctions.

    • Location: Found exclusively in the heart.

    • Control: Involuntary control via the autonomic nervous system.

  • Smooth Muscle:

    • Appearance: Small cells with tapered ends that can function individually or as a multi-unit.

    • Location: Found in blood vessels, the digestive tract, bronchial tubes, and various organs.

    • Control: Involuntary control via the autonomic nervous system.

Functions of the Muscular System
  • Movement: Generates body movements through muscle contractions.

  • Stabilization: Helps maintain body position and posture.

  • Internal Movement: Coordinates the movement of internal organs and systems.

  • Blood Flow Regulation: Influences blood circulation within the body.

  • Heat Production: Generates heat through muscle activity to maintain body temperature.

Muscle Structure Terminology
  • Sarcoplasm: Cytoplasm of a muscle cell.

  • Sarcolemma: Plasma membrane of a muscle cell.

  • Sarcoplasmic Reticulum: The smooth endoplasmic reticulum in muscle cells, which serves to store calcium ions.

Muscular Movement
  • Attachments:

    • Tendons: Connective tissue connecting muscle to bone.

    • Origin: The attachment point of a muscle on a stationary bone.

    • Insertion: The attachment point of a muscle on the moving bone.

  • Action:

    • Antagonistic Muscles: Muscles that function in opposition to each other.

    • Synergistic Muscles: Groups of muscles that work together for a common action.

    • Agonist: The primary muscle responsible for a specific movement during contraction.

Muscle Energy Sources
  • Muscles utilize glycogen, triglycerides, and creatine phosphate (stored in sarcoplasm) to generate ATP.

  • Upon depletion of these sources, glucose and fatty acids may enter muscle cells.

ATP Sources
  • Creatine Phosphate Pathway: The fastest method for muscle ATP acquisition but lasts for only seconds, replenishes during rest.

  • Fermentation: An anaerobic process that produces ATP but leads to lactate accumulation.

  • Cellular Respiration: An aerobic mechanism that, while not immediate, provides the best long-term ATP supply.

Muscular Diseases
  • Fibromyalgia: A condition characterized by chronic muscle pain with an unclear etiology.

  • Myalgia: General muscle pain often resulting from infections or overexertion.

  • Muscular Dystrophy: A collection of genetic disorders causing progressive muscle degeneration and weakness.

  • Myasthenia Gravis: An autoimmune condition that targets acetylcholine receptors, resulting in muscle weakness, particularly in facial and neck muscles.

  • Amyotrophic Lateral Sclerosis (ALS): Also known as Lou Gehrig’s disease, marked by the degeneration of motor neurons that control voluntary muscle movements.

Homeostasis: Interaction between Skeletal and Muscular Systems
  • The skeletal and muscular systems facilitate movement, responding to stimuli and ensuring digestion, respiratory activities, and blood return to the heart.

  • They offer protection to internal organs and minerals stored in bones contribute to muscle contraction and neurological function.

  • Blood cells are generated within bone marrow, while muscle activity helps regulate body temperature.

Summary
  • The skeletal system is responsible for structural support, movement, protection of organs, mineral storage, and blood cell production.

    • Bone types include compact and spongy influenced by their structural functions.

    • Bones are classified into five categories: long, short, flat, irregular, and sesamoid.

  • The muscular system consists of skeletal, smooth, and cardiac tissues with various functions including motion, posture stabilization, regulation, and heat generation.

    • Muscle cells, each called a fiber, require ATP acquired through creatine phosphate, glycolysis, or oxidative phosphorylation.

Objectives
  • Examine the structure and function of skeletal and muscular systems.

  • Identify various bone types and structures.

  • Explain the skeletal system's functions.

  • Distinguish between different types of bone.

  • Describe osteoporosis and its effects.

  • Clarify the roles of ligaments and tendons.

  • Investigate how muscles obtain ATP.

  • Summarize the interconnection between bones and muscles for movement.

  • Define muscle-specific terminology.

  • Examine muscular diseases affecting function.