Menstrual Cycle
Menstrual Cycle Overview
Reference: Brunners Chapter 50
Important Structures - Ovary
Ovaries: Each girl is born with thousands of egg follicles halted at a developmental stage.
Maturation Process:
Monthly after puberty, many follicles begin to mature.
Only one follicle dominates and matures into an egg; others regress.
Important Structures - Graafian Follicle and Corpus Luteum
Graafian Follicle: The dominant egg follicle that eventually releases an egg.
Corpus Luteum:
Formed from the Graafian Follicle post-ovulation.
Acts as a temporary endocrine structure, releasing progesterone and estrogen to support the endometrium if fertilization occurs.
Important Structures - Uterus
Uterine Lining (Endometrium):
Inner lining of the uterus that sheds each month in the absence of pregnancy.
Rebuilt by estrogen during the follicular phase of the menstrual cycle.
If pregnancy occurs, the fertilized egg implants in the endometrium, leading to placenta formation.
Important Hormones Involved
Hypothalamus: Secretes Gonadotropin-Releasing Hormone (GnRH) which signals the pituitary gland.
Pituitary Gland: Releases Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH) in response to GnRH.
Important Hormones
Graafian Follicle: Produces estrogen.
Corpus Luteum: Produces progesterone and estrogen.
Fertilized Egg: Secretes Human Chorionic Gonadotropin (hCG) until the placenta can take over its production.
Ovarian Cycle & Uterine Cycle
Cycle Breakdown:
Ovarian Cycle:
Follicular Phase: Days 1-14
Ovulation: Day 14
Luteal Phase: Days 15-28
Uterine Cycle:
Menstrual Phase: Days 1-6
Proliferative Phase: Days 7-14
Secretory Phase: Days 15-28
Putting It All Together
Ovarian Cycle:
Follicular Phase:
FSH induces growth in several follicles; one matures (Graafian Follicle).
Graafian Follicle releases estrogen, reducing FSH and increasing LH.
Ovulation occurs 24-36 hours after the LH peak.
Egg is viable for 24 hours, sperm for up to 5 days; fertilization typically occurs in the fallopian tube.
Fertility window: Days 9-16.
Luteal Phase:
Corpus luteum forms, releasing estrogen and progesterone.
If no pregnancy, corpus luteum degenerates within 14 days, causing estrogen/progesterone levels to drop, restarting the cycle with GnRH release.
If pregnant, the fertilized egg implants, and the placenta develops.
Uterine Cycle:
Menstrual Phase: Days 1-6; off shedding of the endometrium.
Proliferative Phase: Days 7-14; endometrium rebuilds due to estrogen.
Secretory Phase: Days 15-28; progesterone from cyst prepares endometrium for implantation.
Chapter 46 - Sexuality
Key Concepts:
Gender Identity: Psychological identification of oneself.
Sexual Orientation: Attraction towards individuals (physically, emotionally, romantically).
Gender-Related Terms
Gender Identity: Personal sense of being male, female, or nonbinary; may not align with biological sex.
Gender Expression: How one presents their gender externally.
Gender Diverse: A spectrum of gender expressions outside normative boundaries.
Gender Dysphoria: Distress from mismatch of gender assigned at birth and experienced gender identity.
Cisgender: Gender identity aligns with biological sex.
Transgender: Identifying as a different gender than assigned at birth.
Sexual Orientation
Heterosexual: Opposite gender attraction.
Gay/Lesbian: Same-gender attraction.
Bisexual: Attraction to multiple genders.
Questioning: Uncertainty regarding one's sexual orientation.
Sexual Behavior
Adaptive Behaviors:
Consensual between adults, mutually satisfying, non-harmful, non-coerced, private.
Maladaptive Behaviors:
Lack one or more criteria of adaptive behavior.
Factors Affecting Sexuality
Developmental Considerations: Psychological, emotional, and biological development throughout a lifespan.
Culture: Societal norms impacting views on sexuality.
Religion: Influence on sexual practices and beliefs.
Ethics: Consideration of moral implications of sexual behaviors.
Lifestyle: Impact of stress and responsibilities on sexual health.