Cell: The Unit of Life

CELL: THE UNIT OF LIFE

UNIT-1: Basic Biology
  • Syllabus Overview:

    • The cell as the unit of life

    • Protoplasm and the structure of prokaryotic vs. eukaryotic cells

    • Differences between animal and plant cells

    • Overview of cell theory and cell organelles:

    • Protoplasm, Cytoplasm, Cell Wall, Cell Membrane, Nucleus, Nucleolus, Mitochondria, Endoplasmic Reticulum, Ribosome, Golgi Bodies, Plastids, Lysosomes, Centrosome, and Vacuole.

2.1 What is a Cell?
  • Definition:

    • Fundamental structural and functional unit of all living beings.

    • Smallest unit capable of independent existence and essential life functions.

  • Composition of Organisms:

    • Composed of numerous cells (e.g., skin, brain, plants).

  • Cell Lifespan:

    • Lifecycles involve continuous cell death and regeneration, starting from a single cell (egg).

  • Visibility:

    • Cells are microscopic and require magnification to be viewed.

2.2 The Invention of the Microscope
  • Antony van Leeuwenhoek:

    • Developed first simple microscope with single lens, magnifying up to 200 times.

  • Robert Hooke:

    • Created a compound microscope and coined the term "cells" after observing cork cells.

  • Advancements:

    • Electron microscope developed for magnifications over 200,000 times.

    • Uses beams of electrons compared to light in traditional microscopes.

2.3 Cell Theory
  • Founders: Matthias Schleiden (1838) and Theodor Schwann (1839)

  • Key Points:

    1. The cell is the smallest unit of structure in all living things.

    2. The cell is the unit of function in all living things.

    3. All cells arise from pre-existing cells (Rudolf Virchow, 1858).

  • Examples:

    • Cellular structure seen in tissues of frogs and mango plants.

    • Functions performed by cells are crucial to the organism's activities.

2.4 Cells - How Numerous?
  • Single-celled Organisms: Bacteria, yeast, amoeba.

  • Few-celled Organisms: Spirogyra, Volvox.

  • Multi-celled Organisms: Humans, Mango, etc.

  • Human Cell Count:

    • Approximately 1,000 million million cells in an adult human.

2.5 Cells - How Small?
  • Smallest Cells: Bacteria (0.3-5 micrometers), red blood cells (7 micrometers).

  • Largest Cells: Ostrich egg, a single cell before development.

  • Efficiency of Small Cells:

    • Rapid communication between regions, large surface area-to-volume ratio enhances diffusion.

2.6 Cell Shapes to Suit Functional Requirements
  • Shape Variations:

    • Epithelial cells, muscle cells, nerve cells, etc.

  • Function-Shape Relationship:

    • Example: Red blood cells are biconcave for efficient oxygen transport.

2.7 Structure of a Cell
  • Generalized Cell Structure:

    • Composed of three main parts: Cell membrane, Nucleus, Cytoplasm.

  • Cell Organelles:

    • Miniature organs performing specific functions (e.g., mitochondria for energy production).

2.7.1 Cell Membrane and Cell Wall
  • Cell Membrane:

    • Semi-permeable, regulates substance entry and exit.

  • Cell Wall: (Plant cells only)

    • Rigid structure providing shape and support, made of cellulose.

2.7.2 Cytoplasm
  • Definition: Semi-liquid substance where chemical reactions occur.

  • Components Include:

    • Endoplasmic Reticulum, Mitochondria, Golgi Apparatus, Ribosomes, etc.

2.7.3 Nucleus
  • Importance:

    • Controls cell functions, regulates cell division, carries genetic information.

  • Components:

    • Nuclear membrane, nucleoplasm, chromatin fibers (which condense to chromosomes during cell division).

2.8 The Plant and Animal Cells
  • Similarities: Both have cell membranes, cytoplasm, and organelles.

  • Differences:

    • Plant cells have cell walls, plastids, and larger vacuoles; animal cells have centrosomes and smaller vacuoles.

2.9 Protoplasm
  • Definition: Living substance in cells, includes nucleus and cytoplasm.

  • Chemical Composition: Carbon, hydrogen, oxygen, nitrogen, etc.

2.10 Prokaryotic and Eukaryotic Cells
  • Prokaryotic: No defined nucleus (e.g., bacteria).

  • Eukaryotic: Defined nucleus present (e.g., plants, animals).

2.11 Cellular Activities
  • Core Functions: Growth, repair, movement, nutrient absorption, waste excretion, and reproduction depend on cellular activities.