Digestion, Absorption, and Metabolism Practice Flashcards

Overview of the Gastrointestinal System

  • Structures Involved in the Digestive System:

    • Mouth: The entry point for food.

    • Teeth: Used for mechanical breakdown.

    • Tongue: Facilitates movement of food.

    • Pharynx: Connects the oral cavity to the esophagus.

    • Esophagus: The passage to the stomach.

    • Stomach: Site of chemical and mechanical digestion.

    • Small Intestine: Divided into the duodenum, jejunum, and ileum.

    • Large Intestine: Divided into the cecum, ascending colon, transverse colon, descending colon, sigmoid colon, rectum, and anus.

    • Anus: Terminal end for waste elimination.

  • Accessory Organs:

    • Salivary Glands: Secrete saliva to begin digestion.

    • Liver: Produces bile.

    • Gallbladder: Concentrates and stores bile.

    • Pancreas: Secretes digestive juices and produces insulin.

Eating and Swallowing Processes

  • Pathway:

    • Starts in the Mouth.

    • Moves through the Pharynx.

    • Enters the Esophagus.

  • Esophageal Sphincters:

    1. Pharyngoesophageal Sphincter: Located where swallowing begins.

    2. Gastroesophageal or Lower Esophageal Sphincter (LES): Prevents gastric reflux from the stomach back into the esophagus.

Functions of the Oral Cavity and Salivary Glands

  • Mouth:

    • Recognized as the first part of the digestive tract.

    • Contains the tongue and teeth; receives secretions from salivary glands.

    • Tongue: Composed mostly of skeletal muscle; it is the most movable organ in the mouth.

    • Teeth: Adults have a total of 3232 permanent teeth, categorized into:

      • Cuspids

      • Incisors

      • Bicuspids

      • Molars

    • General Function: Receives food and breaks it down into smaller pieces; mixes food with saliva to initiate the digestive process.

  • Parotid Glands:

    • These are the largest salivary glands.

    • There is one on each side, located anterior and inferior to the ear.

    • They secrete saliva into the mouth to begin the chemical digestion of starches.

The Pharynx and Esophagus

  • Pharynx:

    • Connects the nasal and oral cavities specifically to the esophagus.

    • Food is forced into the pharynx by the action of the tongue.

  • Esophagus:

    • A muscular tube approximately 20cm20\,\text{cm} long.

    • Propels food from the pharynx into the stomach via muscular contractions.

    • The lining of the esophagus secretes mucus to facilitate passage.

The Stomach: Structure and Gastric Function

  • Location and Capacity:

    • Located in the upper-left quadrant of the abdomen.

    • Has a capacity of approximately 1.5L1.5\,\text{L}.

  • Structural Features:

    • Equipped with two sphincters.

    • Acts as a temporary storage place for food.

  • Primary Functions:

    • Regulates the rate of gastric emptying.

    • Secretes gastric juice, which includes hydrochloric acid (HClHCl).

    • Secretes gastric hormones and intrinsic factor.

    • Mixes food with digestive juices, changing it into a semiliquid state.

    • Begins the digestion of proteins.

    • Absorbs vitamin B12B_{12} and other limited substances.

    • Digests a limited amount of food.

The Small Intestine

  • Anatomical Parts:

    • Duodenum: The first segment.

    • Jejunum: The middle segment.

    • Ileum: The final segment.

  • Primary Functions:

    • Digestion and Absorption: Finishes digestion and absorbs nutrients.

    • Mixing: Mixes food with secretions from the liver and pancreas.

    • Hormone and Enzyme Secretion: Secretes hormones and digestive enzymes, including Secretin and Cholecystokinin.

  • Absorption Microstructure (Duodenum):

    • Contains Villi and Microvilli: These folds significantly increase the surface area available for absorption.

    • The interior of these structures is composed of capillaries and lacteals.

    • Absorbed end products of digestion are delivered to the hepatic portal system and lymphatics.

The Large Intestine and Accessory Organs

  • Large Intestine Anatomy:

    • Cecum.

    • Vermiform Appendix.

    • Colon: Includes the Ascending, Transverse, Descending, and Sigmoid segments.

    • Rectum and Anus.

  • Large Intestine Functions:

    • Absorption of water and electrolytes.

    • Synthesis of vitamins by intestinal bacteria.

    • Temporary storage of waste products.

    • Elimination of waste (feces) and gas (flatus).

  • Additional Accessory Functions:

    • Liver and Gallbladder: Work together to concentrate, store, and secrete bile into the duodenum.

    • Pancreas: Secretes digestive juices to aid digestion and produces insulin for glucose regulation.

Essential Nutrition and Digestion Terminology

  • Ingestion: The process of consuming food by the mouth and moving it through the digestive system.

  • Digestion: A systemic process that includes the breakdown and absorption of nutrients.

  • Absorption: Occurs as components of nutrients pass through the digestive system into the bloodstream and lymphatic system.

  • Metabolism: The sum of all chemical processes that occur on a cellular level to maintain homeostasis.

    • Catabolism: The breaking down of substances with the resultant release of energy.

    • Anabolism: The use of energy to build or repair substances.

Protein: Roles and Requirements

  • Importance: A constant supply is essential for rebuilding and replacing body tissues.

  • Biological Roles: Hormone production, fluid balance, antibody production, and transportation of nutrients.

  • Energy Content: Supplies approximately 4calories/g4\,\text{calories/g}.

  • Composition: Composed of amino acids:

    • 99 essential amino acids.

    • 1111 nonessential amino acids.

  • Sources:

    • Animal Sources: Red meat, eggs, milk and milk products, poultry, fish. These are considered Complete or high-quality proteins.

    • Plant Sources: Grains, legumes, and most vegetables. These are considered Incomplete or low-quality proteins.

  • Protein Excess:

    • Stressful to the liver and kidneys.

    • Kidneys must work to rid the body of excess waste products.

    • The liver's function is strained with the excess load metabolizing protein.

    • Can lead to excess fat in the diet.

Dietary Fiber

  • Definition: The portion of the carbohydrate that cannot be broken down during digestion. It passes through the intestine undigested.

  • Functions:

    • Increases bulk in the stool.

    • Aids in elimination.

    • May decrease the absorption of fat.

  • Recommended Intake: 2121 to 38g/day38\,\text{g/day}.

  • Sources:

    • Fruits: Apples, bananas, oranges, grapefruits, cantaloupe, strawberries.

    • Vegetables: Green beans, broccoli, cauliflower, celery, corn, potato (with skin), sweet potato.

    • Grains and Cereals: Breads, All Bran, oatmeal, Shredded Wheat.

    • Legumes (cooked): Kidney beans, pinto beans, lima beans, black-eyed peas.

Basal Metabolic Rate (BMR)

  • Definition: BMR is the number of calories the body needs to stay alive and function at rest (e.g., breathing, heart beating, maintaining body temperature).

  • Factors Affecting BMR:

    • Lean body mass.

    • Hormones.

    • Body surface area.

    • Age.

    • Sex.

    • Medications.

    • Disease.

    • Pregnancy.

    • Malnutrition.

Aging and the Digestive System

  • Oral/Upper GI Changes:

    • Dental Caries and Tooth Loss: Decrease a person’s ability to chew food.

    • Decreased Gag Reflex: Increases the risk of aspiration.

    • Decreased Sense of Taste: May lead to a loss of appetite.

    • Decreased Muscle Tone at Sphincters: Increases the risk of esophageal (acid) reflux.

  • Lower GI/Systemic Changes:

    • Decreased Gastric Secretions: May interfere with the overall digestion of food.

    • Decreased Peristalsis: Increases the risk of constipation.

Metabolism and Energy Management

  • Biological Process:

    • Large molecules are broken down into smaller molecules to make energy available to the organism.

    • Enables absorbed nutrients to enter the bloodstream after digestion.

    • Digestion converts food into chemical substances like proteins and simple sugars to be used for energy production and cellular metabolism.

  • Consequences of Slow Metabolism:

    • Weight gain (if calorie intake stays the same).

    • Fatigue or low energy.

    • Cold sensitivity.

    • Slow digestion.

    • Difficulty losing weight.

  • Strategies to Increase Metabolism:

    • Building Muscle: Muscle burns more calories than fat, even at rest.

    • Staying Active: Regular exercise, especially strength training and cardio.

    • Eating Enough: Skipping meals or eating too little can slow metabolism.

    • Eating Protein-rich Foods: Protein takes more energy to digest and supports muscle growth.

    • Drinking Water: Hydration helps the body burn calories efficiently.

    • Getting Enough Sleep: Poor sleep can lower metabolism and increase weight gain.", "title": "Comprehensive Study Notes on Digestion, Absorption, and Metabolism"}