USABO2


Unit 1: The Chemistry of Life

Life is based on chemical principles, and understanding the molecules that make up organisms is essential.

1. The Chemical Context of Life

  • Atoms are the building blocks of matter, made of protons, neutrons, and electrons.

  • Chemical bonds (covalent, ionic, hydrogen, van der Waals) determine molecular interactions.

  • Water has unique properties (cohesion, adhesion, high heat capacity, solvent abilities) crucial for life.

2. Carbon and the Molecular Diversity of Life

  • Carbon forms the backbone of biological molecules.

  • Functional groups (hydroxyl, carboxyl, amino, phosphate) influence chemical properties.

  • Isomers are molecules with the same formula but different structures and functions.

3. The Structure and Function of Large Biological Molecules

  • Carbohydrates: Provide energy and structure (sugars, starch, cellulose).

  • Lipids: Hydrophobic molecules used for energy storage, insulation, and membranes (fats, phospholipids, steroids).

  • Proteins: Perform most cell functions (enzymes, transport, structure).

  • Nucleic Acids: Store genetic information (DNA, RNA).


Unit 2: The Cell

Cells are the basic unit of life, and their structure and function are critical for survival.

4. A Tour of the Cell

  • Prokaryotic cells (bacteria, archaea) lack nuclei and organelles, while eukaryotic cells (plants, animals) have them.

  • Organelles like mitochondria, the nucleus, and ribosomes perform specialized functions.

5. Membrane Transport and Cell Signaling

  • Cell membranes are semi-permeable, controlling what enters and exits.

  • Passive transport (diffusion, osmosis) doesn’t use energy, while active transport (pumps, endocytosis) does.

  • Cells communicate via chemical signals that bind to receptors and trigger responses.

6. An Introduction to Metabolism

  • Metabolism includes all chemical reactions in cells.

  • Enzymes speed up reactions by lowering activation energy.

  • ATP is the energy currency of the cell, used in reactions requiring energy.


Unit 3: Genetics

Genetics explains how traits are inherited and how cells use genetic information.

7. Cellular Respiration and Fermentation

  • Cells make ATP using glucose in three steps: glycolysis, Krebs cycle, oxidative phosphorylation.

  • Oxygen is required for aerobic respiration, while fermentation happens without oxygen.

8. Photosynthesis

  • Plants use sunlight to convert CO₂ and H₂O into glucose and oxygen.

  • The light reactions capture energy, and the Calvin cycle makes sugar.

9. The Cell Cycle

  • Cells grow and divide through mitosis (for growth and repair).

  • Checkpoints regulate cell division; cancer results when these fail.

10. Meiosis and Sexual Life Cycles

  • Meiosis produces gametes with half the chromosome number, introducing genetic variation.

  • Fertilization restores the full chromosome count.

11. Mendelian Genetics

  • Traits follow predictable inheritance patterns based on dominant and recessive alleles.

  • Punnett squares help predict offspring traits.

12. Chromosomal Basis of Inheritance

  • Genes are on chromosomes; crossing over increases variation.

  • Mistakes in chromosome number (nondisjunction) can cause disorders like Down syndrome.

13. Molecular Basis of Inheritance

  • DNA replication ensures genetic information is passed on.

  • Errors can lead to mutations, some of which cause diseases.

14. Gene Expression

  • DNA is transcribed into RNA, which is translated into proteins.

  • Gene regulation allows cells to turn genes on and off.

15. Biotechnology

  • Scientists use techniques like PCR, CRISPR, and cloning to study and modify DNA.


Unit 4: Mechanisms of Evolution

Evolution explains how life changes over time.

16. Darwinian Evolution

  • Natural selection favors traits that improve survival and reproduction.

  • Fossil evidence and comparative anatomy support evolution.

17. Population Genetics

  • Evolution happens when allele frequencies change in a population.

  • Mutations, genetic drift, and gene flow contribute to variation.


Unit 5: The Evolutionary History of Life

How life originated and diversified.

18. Phylogeny and the Tree of Life

  • Organisms are classified based on evolutionary relationships.

  • Phylogenetic trees show common ancestors and speciation events.


Unit 6: Plant Form and Function

Plants have specialized structures for growth, transport, and reproduction.

19. Plant Structure, Growth, and Development

  • Meristems allow plants to grow continuously.

  • Roots, stems, and leaves have different functions.

20. Resource Acquisition and Transport in Plants

  • Water moves through xylem via transpiration.

  • Sugars are transported in phloem from sources (leaves) to sinks (roots).

21. Reproduction and Development of Flowering Plants

  • Angiosperms reproduce via flowers, using pollen and ovules.

  • Seeds contain embryos that grow into new plants.


Unit 7: Animal Form and Function

Animals rely on specialized organ systems to maintain homeostasis.

22. Animal Structure and Function

  • Tissues (muscle, epithelial, connective, nervous) make up organs and systems.

  • Homeostasis keeps internal conditions stable.

23. Animal Nutrition

  • Digestive systems break down food for energy and nutrients.

  • Some animals have specialized diets and adaptations.

24. Circulation and Gas Exchange

  • The heart and blood vessels transport oxygen and nutrients.

  • The lungs or gills exchange oxygen and carbon dioxide.

25. The Immune System

  • The body defends against pathogens using innate and adaptive immunity.

  • Vaccines help develop immunity by training the immune system.

26. Hormones and the Endocrine System

  • Hormones control processes like growth and metabolism.

  • The endocrine system communicates via chemical messengers.

27. The Nervous System

  • Neurons transmit signals via electrical impulses.

  • The brain and spinal cord coordinate body functions.

28. Muscles and Movement

  • Skeletal, cardiac, and smooth muscle enable movement and organ function.

  • Muscles contract by sliding filaments (actin and myosin).


Unit 8: Ecology

Ecology studies how organisms interact with each other and their environment.

29. Ecosystems and the Biosphere

  • Biomes are large ecosystems with unique climates and species.

  • Energy flows through food chains, with producers at the base.

30. Population Ecology

  • Populations grow based on birth and death rates.

  • Carrying capacity limits growth due to resource availability.

31. Community Ecology

  • Species interact as predators, competitors, or mutualists.

  • Keystone species play a critical role in ecosystems.

32. Conservation Biology

  • Biodiversity is important for ecosystem stability.

  • Human activities impact climate and ecosystems, leading to conservation efforts