Unit 1: Chemistry of Life
1.1: Structure of Water + Hydrogen Bonding
Water’s electronegativity and polarity allows hydrogen bonding
Properties of water that result from Hydrogen Bonding
Adhesion: Allows water molecules to stick to other substances (Ex: how water moves up the xylem in plants
Cohesion: Water’s ability to stick to itself
High Heat Capacity: Allows water to retain its temperature & effective heat transfer, making it easier to buffer extreme temperatures and climate
Density: Water is less dense when frozen
1.2: Elements of Life
The major elements of life: Hydrogen, Oxygen, Carbon, Nitrogen
Carbon is the building block of life
4 valence electrons
Used to form every macromolecule
1.3-1.5: Biological Macromolecules
Carbohydrates
Disaccharides formed from monosaccharides like glucose from dehydration synthesis, and broken down by hydrolysis
Disaccharides form polysaccharides: a long chain of monosaccharides
Used for energy and stored as starch in plants, and glycogen in animals. If the body is at max glycogen capacity, it’s turned into triglycerides.
Cellulose: provides structural support in plants and cannot be broken down by hydrolysis due to its bond arrangement
Lipids
Non polar and makes up triglycerides, phospholipids, and sterols
Saturated fats cannot have double bonds and are solid at room temperature because of the tight hydrogen packing, while unsaturated fat can double bond and is liquid at room temp.
Phospholipids: Amphipathic and make up the cell membrane
Proteins
Forms enzymes
Made up of a carboxyl group, an amino group, and a variable R group that determines the properties of the amino acid
The free carboxyl group bonds to the amino group
(1): Primary structure: Which order amino acids are bonded together
(2): Secondary structure: Alpha and Beta helices with hydrogen bonding in the middle
(3) Tertiary structure: The R groups interact with each other, causing folding
(4) Quaternary structure: An arrangement of multiple protein chains held together by hydrogen bonds
1.6: Nucleic Acids
DNA
Monomer: Nucleotides
Made up of antiparallel strands with alternating 5’ and 3’ ends
Contains a phosphate group, deoxyribose, and nitrogenous base
The base sequence forms DNA’s structure and happens because of hydrogen bonds
RNA
Monomer: Nucleotides
Uracil instead of Thymine
Made up of ribose instead of Deoxyribose
Unit 2: Cell Structure and Function
2.1-2.2: Organelles
Nucleus: The double-membraned control center of the cell
Ribosomes: Site of protein synthesis
Lysosomes (Animal Cells Only): Breaks down waste and helps with apoptosis
Endoplasmic Reticulum: The “highway of the cell” helping with mechanical function
Rough: Makes proteins
Smooth: makes lipids and breaks down toxins
Mitochondria: Produces ATP and energy
Centriole: aids in cell division
Cytoskeleton: Provides structural support and has 3 filaments with a link to ALS
Golgi Apparatus: packages, modifies, and transports proteins and lipids w/ vesicles
Chloroplasts: Thylakoids and Stroma, converts light into sugar
2.3 Cell Size
A cell’s surface area and volume affects their ability for resources and energy
Smaller cell= a bigger surface area to volume ratio
The surface area needs to be big enough to supply the cell with nutrients
Microvilli are used by cells to increase the surface area without increasing volume
2.4-2.5: Plasma Membrane
The plasma membrane is amphipathic, flexible, and maintains homeostasis by controlling what goes in and out of the cell
Small, non polar molecules can easily pass through while large polar molecules and ions cannot
Water passes through aquaporins (protein channels), allowing a cell to change it’s permeability
Integral proteins cross the whole membrane while peripheral proteins stay outside
2.6-2.7, 2,9: Membrane Transport
Simple diffusion: natural diffusion of small, nonpolar molecules into the cell
Passive transport: Doesn’t require ATP, moves high to low concentration
Facilitated diffusion: Molecules that can’t pass through naturally diffuse through a transmembrane protein (high to low)
Active transport: Uses ATP to move ions across a concentration gradient from low to high concentration (ex: sodium-potassium pump)
2.8: Tonicity
Hypotonic: low concentration
Hypertonic: high concentration
Water moves by osmosis from a low to high concentration.
A carrot placed in water will swell because the carrot has a higher solute concentration than the water
A carrot placed in salt water will shrink because salt water has a higher concentration than the carrot
2.10: Cell Compartmentalization
Cells have membranes to separate their internal environments from their external environments
This allows metabolic reactions to occur, ensures efficient reactions and minimizes competing interactions in different organelles
2.11: Endosymbiosis Theory
Theory that a prokaryote was engulfed by a eukaryotic cell through endocytosis, and their relationship was symbiotic, causing the cell to continue to evolve like that.
Evidence of this comes from double membraned organelles such as chloroplasts and the mitochondriaUnit 1: Chemistry of Life
1.1: Structure of Water + Hydrogen Bonding
Water’s electronegativity and polarity allows hydrogen bonding
Properties of water that result from Hydrogen Bonding
Adhesion: Allows water molecules to stick to other substances (Ex: how water moves up the xylem in plants
Cohesion: Water’s ability to stick to itself
High Heat Capacity: Allows water to retain its temperature & effective heat transfer, making it easier to buffer extreme temperatures and climate
Density: Water is less dense when frozen
1.2: Elements of Life
The major elements of life: Hydrogen, Oxygen, Carbon, Nitrogen
Carbon is the building block of life
4 valence electrons
Used to form every macromolecule
1.3-1.5: Biological Macromolecules
Carbohydrates
Disaccharides formed from monosaccharides like glucose from dehydration synthesis, and broken down by hydrolysis
Disaccharides form polysaccharides: a long chain of monosaccharides
Used for energy and stored as starch in plants, and glycogen in animals. If the body is at max glycogen capacity, it’s turned into triglycerides.
Cellulose: provides structural support in plants and cannot be broken down by hydrolysis due to its bond arrangement
Lipids
Non polar and makes up triglycerides, phospholipids, and sterols
Saturated fats cannot have double bonds and are solid at room temperature because of the tight hydrogen packing, while unsaturated fat can double bond and is liquid at room temp.
Phospholipids: Amphipathic and make up the cell membrane
Proteins
Forms enzymes
Made up of a carboxyl group, an amino group, and a variable R group that determines the properties of the amino acid
The free carboxyl group bonds to the amino group
(1): Primary structure: Which order amino acids are bonded together
(2): Secondary structure: Alpha and Beta helices with hydrogen bonding in the middle
(3) Tertiary structure: The R groups interact with each other, causing folding
(4) Quaternary structure: An arrangement of multiple protein chains held together by hydrogen bonds
1.6: Nucleic Acids
DNA
Monomer: Nucleotides
Made up of antiparallel strands with alternating 5’ and 3’ ends
Contains a phosphate group, deoxyribose, and nitrogenous base
The base sequence forms DNA’s structure and happens because of hydrogen bonds
RNA
Monomer: Nucleotides
Uracil instead of Thymine
Made up of ribose instead of Deoxyribose
Unit 2: Cell Structure and Function
2.1-2.2: Organelles
Nucleus: The double-membraned control center of the cell
Ribosomes: Site of protein synthesis
Lysosomes (Animal Cells Only): Breaks down waste and helps with apoptosis
Endoplasmic Reticulum: The “highway of the cell” helping with mechanical function
Rough: Makes proteins
Smooth: makes lipids and breaks down toxins
Mitochondria: Produces ATP and energy
Centriole: aids in cell division
Cytoskeleton: Provides structural support and has 3 filaments with a link to ALS
Golgi Apparatus: packages, modifies, and transports proteins and lipids w/ vesicles
Chloroplasts: Thylakoids and Stroma, converts light into sugar
2.3 Cell Size
A cell’s surface area and volume affects their ability for resources and energy
Smaller cell= a bigger surface area to volume ratio
The surface area needs to be big enough to supply the cell with nutrients
Microvilli are used by cells to increase the surface area without increasing volume
2.4-2.5: Plasma Membrane
The plasma membrane is amphipathic, flexible, and maintains homeostasis by controlling what goes in and out of the cell
Small, non polar molecules can easily pass through while large polar molecules and ions cannot
Water passes through aquaporins (protein channels), allowing a cell to change it’s permeability
Integral proteins cross the whole membrane while peripheral proteins stay outside
2.6-2.7, 2,9: Membrane Transport
Simple diffusion: natural diffusion of small, nonpolar molecules into the cell
Passive transport: Doesn’t require ATP, moves high to low concentration
Facilitated diffusion: Molecules that can’t pass through naturally diffuse through a transmembrane protein (high to low)
Active transport: Uses ATP to move ions across a concentration gradient from low to high concentration (ex: sodium-potassium pump)
2.8: Tonicity
Hypotonic: low concentration
Hypertonic: high concentration
Water moves by osmosis from a low to high concentration.
A carrot placed in water will swell because the carrot has a higher solute concentration than the water
A carrot placed in salt water will shrink because salt water has a higher concentration than the carrot
2.10: Cell Compartmentalization
Cells have membranes to separate their internal environments from their external environments
This allows metabolic reactions to occur, ensures efficient reactions and minimizes competing interactions in different organelles
2.11: Endosymbiosis Theory
Theory that a prokaryote was engulfed by a eukaryotic cell through endocytosis, and their relationship was symbiotic, causing the cell to continue to evolve like that.