Lecture Notes on Sleep and Sleep Disorders

Sleep Theories

  • Importance of sleep in humans and animals is evident; few species don't sleep.

  • Restore and Repair Hypothesis: Sleep facilitates body maintenance, such as restoring glycogen and clearing brain waste, but lacks substantial supporting evidence.

  • Preserve and Protect Hypothesis: Evolutionary perspective suggesting sleep maximizes safety during vulnerable times; species with higher predatory risks sleep less.

Sleep and Cognitive Function

  • Sleep is linked to learning and memory enhancement, especially in youth.

  • Research shows that sleep after learning tasks can improve performance (e.g., finger tapping tasks).

  • REM sleep (20-25% of total sleep) is crucial for memory; REM rebound occurs after deprivation.

Dreaming Theories

  • Dreams occur during non-conscious sleep; elaborate dreams are recalled from REM sleep.

  • Freudian Theory: Dreams symbolize unconscious desires (manifest vs. latent content).

  • Activation-Synthesis Hypothesis: Dreams stem from brainstem activity interpreted by the cortex, contributing to a proto-conscious state.

Sleep Disorders

  • Insomnia: Common sleep disorder impacting daily function, consists of:

    • Onset insomnia: Trouble falling asleep.

    • Maintenance insomnia: Trouble staying asleep.

    • Early-morning insomnia: Waking too early.

  • REM Behavior Disorder: Acting out dreams due to a malfunction in REM paralysis.

  • Narcolepsy: Rare disorder characterized by excessive daytime sleepiness and direct transition to REM sleep; related to orexin deficiency.

Sleep Tips

  • Establish a consistent sleep schedule.

  • Associate your bed with sleep, avoid reading.

  • Get up if unable to sleep until tired.

  • Keep the room cool (around 18.5°C).

  • Avoid caffeine and sedatives before bed.