PA11- Laboratory diagnosis of viral hepatitis and HIV infection

Hepatitis Viruses

Hepatitis viruses are a group of viruses that primarily infect the liver, leading to various forms of hepatitis. Among numerous viruses, five are known to cause primary hepatitis: Hepatitis A (HAV), B (HBV), C (HCV), D (HDV), and E (HEV). These viruses are categorized based on their nucleic acids and modes of transmission, with significant implications for prevention and treatment, as summarized in the following table:

Hepatitis Viruses Summary

Virus

Nucleic Acid

Transmission

Antiviral Treatment

Vaccine

HAV

RNA

Fecal-oral

No

Yes

HBV

DNA

Sexual, Blood

Yes

Yes

HCV

RNA

Blood

Yes

No

HDV

RNA

Sexual, Blood

No

No

HEV

RNA

Fecal-oral

Yes

Yes

Notably, HBV, HCV, and HDV are capable of causing chronic hepatitis, which may progress to severe liver conditions such as cirrhosis and hepatocellular carcinoma.