Computed Tomography Notes

Computed Tomography

Basic Principle of CT Scan

  • Conventional radiographs project a 3D object onto a 2D image, causing superimposition of tissues, which is a major limitation.

Background

  • Tomography originates from the Greek word "tomos," meaning to cut, section, or layer.
  • CT uses computerized methods to acquire and transform data.
  • Components for CT imaging were available 20 years before Hounsfield's demonstration in 1970.
  • Godfrey Hounsfield (EMI, Ltd.) and Alan Cormack (Tufts University) are key figures in CT development.
  • Cormack developed the mathematics for CT image reconstruction and shared the 1979 Nobel Prize in physics with Hounsfield.

Terminology

  • Spatial Resolution: Ability to distinctly define small objects.
  • Low-Contrast Resolution: Ability to differentiate objects with similar densities.
  • Temporal Resolution: Speed of data acquisition, important for reducing motion artifacts (e.g., in cardiac imaging).

Computed Tomography: Defined

  • CT uses a computer to process x-ray beam information from an area of anatomy to create cross-sectional images.
  • Each CT slice represents a specific plane in the patient’s body.
  • Z-axis: Represents the thickness of the CT slice.

CT Image Elements

  • Pixel: A two-dimensional square element (picture element) defined by width (X) and height (Y).
  • A CT image is a composite of thousands of pixels.
  • Voxel: A three-dimensional cube element (volume element) when the Z-axis (slice thickness) is considered.

Illustration of Pixel/Voxel relationship

  • Z axis, Pixel, Voxel shown in relation to each other.

Beam Attenuation

  • Beam Attenuation: The degree to which an x-ray beam is reduced by an object, dependent on:
    • Density
    • Thickness
    • Atomic number
  • Linear Attenuation Coefficient: The amount of the x-ray beam that is scattered or absorbed per unit thickness of the absorber.

Linear Attenuation Coefficient

  • Example: For a 125-kVp x-ray beam, the linear attenuation coefficient for water is approximately 0.18cm10.18 \, cm^{-1}. This means about 18% of the photons are either absorbed or scattered when the x-ray beam passes through 1 cm of water.

Hounsfield Unit (HU)

  • Hounsfield units quantify the degree of x-ray beam attenuation.
    • Bone: +1,000+1,000 HU
    • Distilled Water: 00 HU
    • Air: 1,000-1,000 HU
  • 1 HU equals a 0.1% difference between the linear attenuation coefficient of the tissue compared to water.

Factors Affecting Hounsfield Unit Measurement

  • Poor equipment calibration
  • Image artifacts
  • Volume averaging

Polychromatic X-Ray Beams

  • CT and conventional radiography use polychromatic x-ray beams (photons with varying energies).

Beam Hardening

  • Beam Hardening: Artifact that appears as dark streaks or vague areas of decreased density (cupping artifacts).

Volume Averaging (Partial Volume Effect)

  • Volume averaging occurs when different tissue attenuation values are averaged to produce one less accurate pixel reading.
  • Thicker CT slices increase the likelihood of missing small objects.
  • Example: If 10-mm slices are used and a pathologic tissue measures 2 mm, the 8 mm of normal tissue is averaged in, potentially making the pathologic tissue less apparent.
  • Thinner slices of the same area may be useful if an area scanned produces images that are suspicious for a mass, but not definitive

Volume Averaging Considerations

Why use thicker cuts in some scanning protocols?

  • Radiation Dose: Scanning procedures aim to balance image quality and radiation dose.
  • Large Scan Area: Scanning a large area with thin slices produces a huge number of slices.

Pixel Size and Volume Averaging

  • Larger pixel sizes increase the chance that a pixel will contain tissues of different densities.
  • Example: A pixel containing equal parts calcium (600 HU) and lung tissue (-600 HU) will have a resulting density of 0 HU, which does not accurately reflect either tissue.

Raw Data vs. Image Data

  • Raw Data: Data that have not been sectioned into pixels; Hounsfield unit values have not been assigned.
  • Image Reconstruction: The process of using raw data to create an image.
  • Image Data: Data with assigned Hounsfield unit values used to create an image.
  • Prospective Reconstruction: The reconstruction that is automatically produced during scanning.
  • Retrospective Reconstruction: Using the same raw data later to generate new images.

Scan Modes

  • Step-and-Shoot Scanning (1980s):

    • X-ray tube rotated 360° around the patient to acquire data for a single slice.
    • The motion of the x-ray tube was halted while the patient was advanced on the CT table to the location appropriate to collect data for the next slice.
    • The process was repeated until the desired area was covered.
    • Also known as axial scanning, conventional scanning, or serial scanning.
  • Helical (Spiral) Scanning (1990s):

    • Continuous acquisition scanning mode.
    • Development of systems that eliminated cables allowed for continuous gantry rotation.
    • Uninterrupted data acquisition traces a helical path around the patient.
  • Multidetector Row CT Scanning:

    • The first helical scanners emitted x-rays that were detected by a single row of detectors, yielding one slice per gantry rotation.
    • In 1992, scanners were introduced that contained two rows of detectors, capturing data for two slices per gantry rotation.
    • Further improvements equipped scanners with multiple rows of detectors, allowing data for many slices to be acquired with each gantry rotation.

Imaging Planes

Illustration of imaging planes: Axial, Coronal, Sagittal.

  • Includes anatomical terms and direction indicators like superior, inferior, anterior, posterior, medial, lateral, proximal, and distal.

Overview of CT System Operation

  • CT scan process:
    • Data Acquisition (GET DATA)
    • Image Reconstruction (USE DATA)
    • Image Display (DISPLAY DATA)