26 Digestive Physiology
Page 1
Title: Physiology of the Digestive System
Copyright Information: © 2007, 2003 by Mosby, Inc.
Page 2: Overview of Digestive Function
Primary Function: To bring essential nutrients into the internal environment for cellular availability.
Mechanisms of Digestive System:
Ingestion: Intake of food.
Digestion: Breakdown of complex nutrients into simpler forms.
Motility: Movement and physical breakdown of food through the GI wall.
Secretion: Release of digestive enzymes for chemical digestion.
Absorption: Movement of nutrients into the internal environment via the GI mucosa.
Elimination: Excretion of non-absorbed materials.
Regulation: Coordination of digestive functions.
Digestive tract serves as an extension of the external environment until absorption occurs.
Page 3: Mechanical Digestion
Definition: Movements that change food from large to minute particles, facilitating digestion.
Processes:
Churning contents to mix with digestive juices and enhance absorption contact.
Propelling food along the alimentary tract; eliminating waste.
Mastication: Chewing to reduce food particle size and mix with saliva.
Page 4: Phases of Swallowing (Deglutition)
Oral Stage: Voluntary control; forms bolus on the tongue, pushed to the oropharynx.
Pharyngeal Stage: Involuntary; blocks oral cavity and nasopharynx to propel bolus to esophagus.
Esophageal Stage: Involuntary; movements push the bolus into the stomach.
Page 5: Types of Motility
Peristalsis: Wavelike muscle contractions that move food forward in the GI tract.
Segmentation: Mixing movements that facilitate digestion and absorption by bringing contents in contact with intestinal mucosa.
Page 6: Regulation of Motility
Gastric Motility: Detailed processes of stomach emptying, influenced by hormonal and nervous signals.
Takes approximately 2 to 6 hours. Chyme ejected every 20 seconds.
Hormonal Mechanism: Fats in duodenum release gastric inhibitory peptide, slowing gastric peristalsis.
Nervous Mechanism: Enterogastric reflex inhibits gastric peristalsis based on acid presence and distention.
Intestinal Motility: Includes peristalsis and segmentation; timing of peristalsis increases as chyme approaches the large intestine.