Alcohol+Use+Disorder

EXEMPLAR 22.A: ALCOHOL USE DISORDER

LEARNING OUTCOMES

  • Analyze the manifestations and treatment considerations for patients who abuse alcohol.
  • Describe the pathophysiology of alcohol abuse.
  • Describe the etiology of alcohol abuse.
  • Compare the risk factors and prevention of alcohol abuse.
  • Identify the clinical manifestations of alcohol abuse.
  • Identify the clinical manifestations of alcohol withdrawal.
  • Summarize diagnostic tests and therapies used by interprofessional teams in the collaborative care of an individual with alcohol use disorder.
  • Differentiate care of patients across the lifespan who abuse alcohol.
  • Apply the nursing process to promote patient safety during withdrawal and detoxification.
  • Apply the nursing process in providing culturally competent care to an individual with alcohol use disorder.

OVERVIEW

Alcohol Definition and Importance
  • Alcohol includes various types of beverages such as liquor, beer, and wine.
  • Its widespread availability contributes to its status as the most commonly used and abused substance in the United States.
Economic Burden
  • Estimated cost of alcohol abuse in the United States: $249 billion
      - Includes:
        - Losses in workplace productivity.
        - Healthcare expenses.
        - Law enforcement and other criminal justice expenses.
        - Costs from motor vehicle crashes due to impaired driving.
Understanding Alcoholism
  • Alcoholism is classified as a primary, chronic disease influenced by genetic, psychosocial, and environmental factors.
  • Characterized by behaviors associated with addiction.
  • Alcohol use disorder refers to a chronic disease with specific identifiable manifestations and patterns.
Patterns of Alcohol Dependence
  • Varies widely from individual to individual.
  • Moderate Drinking Guidelines:
      - Men: Up to 2 drinks per day
      - Women: Up to 1 drink per day
  • Drinking behavior patterns can include:
      - Regular consumption of large amounts of alcohol daily.
      - Heavy drinking restricted to weekends or days off.
      - Binge drinking, defined as drinking copious amounts in a single session.
      - Heavy alcohol use, described as consuming 5 or more drinks in one session on at least one day in the past 30 days.
      - Some individuals can abstain for long periods, then resume dysfunctional drinking.
      - Some can control drinking at times but lose control at others.
  • Addiction behaviors increase in frequency over time.

PATHOPHYSIOLOGY

  • Alcohol acts as a central nervous system (CNS) depressant.
  • It affects neurotransmitter dynamics in the brain, decreasing neuronal excitability.
  • Creates an additive effect with gamma-aminobutyric acid (GABA).
  • Absorption occurs in the mouth, stomach, and digestive tract, with the liver metabolizing about 95% of ingested alcohol.
  • Typical breakdown rate: 1.5 oz of distilled spirits every 90 minutes.
      - Factors affecting absorption rate include body mass, food intake, and liver function.

ETIOLOGY AND EPIDEMIOLOGY

  • There are multiple pathways that can lead to alcoholism:
      - Significant influence of genetic and other biological factors.
      - Cognitive, behavioral, temperament, psychological, and sociocultural factors play roles in its development.
      - Familial patterns are frequently observed in alcohol use.
      - Notable ethnic differences in alcohol use behaviors exist, although no intervention translated from research findings on biological differences to treatment strategies.
      - Cultural factors contribute to variability in alcohol abuse across ethnic groups.
      - Co-occurrence of mood and substance disorders, known as dual diagnosis, is common.
      - Medications effective for mood-related symptoms may not positively influence substance use disorder.

RISK FACTORS AND PREVENTION

  • Genetics: Major risk factor in alcohol abuse development.
      - Example: Some American Indians lack genes that alter alcohol-metabolizing enzymes.
  • Sociocultural Factors:
      - Higher rates of substance misuse are often seen in communities with lower educational levels and weak familial relationships.
      - Stigma and discrimination may heighten vulnerability to alcohol abuse.
      - Members of the LGBTQ community are statistically more likely to misuse alcohol and other drugs.

CLINICAL MANIFESTATIONS OF ALCOHOL ABUSE

  • Behavioral Signs:
      - Focus on acquiring alcohol, overuse, inability to stop or reduce drinking, impaired role function, risky consumption, and strong cravings.
  • Physiological Symptoms:
      - Developing tolerance to alcohol or reduced effect from the same amount consumed.
      - Withdrawal symptoms such as tremors when not drinking or increased urgency to drink to avoid symptoms.
      - Moderate alcohol consumption can yield mild euphoric effects, while excess intake can lead to cravings and significantly impaired functioning, potentially culminating in life-threatening conditions.

ALCOHOL INTOXICATION AND OVERDOSE

Alcohol Intoxication (1 of 2