MEDS
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TRADE NAME (GENERIC) | INDICATION | HOW IT WORKS | CONTRA- | DOSE | Side effects |
Adenosine (Adenoncard) | SVT | Decreases electrical conduction through AV node | -hypersensitivity -drug induced tach -bradycardia | 1st-6mg 2nd-12mg 3rd-12mg (fast IV, followed w/ flush) | -Light headedness -hypotension -nausea |
Albuterol (Proventil) (Ventolin)
| Bronchospasm from asthma or COPD | Bronchodilation (beta 2) | Pregnancy (except in life threatening situation) | 1st-2.5mg in 3mL 2nd-same 3rd-same (if NO improvement after first, combine w/ Atrovent) | -tachycardia -hypertension -restlessness |
Alcaine (Proparacaine) | Burns to the eyes or corneal abrasion | Blocks impulses from sensory nerves | -Trauma/Laceration to the eye
-Foreign body allergies to CAINE drugs | 1-2 drops q 5min
MAX of 3 doses | -Initial burning or Stinging Sensations |
Amiodarone HCl (Cordarone)
| VFib & VTach | Blocks Calcium, Na, K Channels | -cardiogenic shock -bradycardia | Adult: VFib/VTach w/o P- 1st-300mg IV/IO 2nd-150mg IV/IO VTach w/ P: 150mg over 10 mins Pediatric: VFib/VTach w/o P- 1st- 5mg/kg (max of 150mg) 2nd-same as 1st VTach w/P: 5mg/kg, drip over 30 mins | -hypotension if given rapid infusion -bradycardia, -CHF |
TRADE NAME (GENERIC) | INDICATION | HOW IT WORKS | CONTRA- | DOSE | Side effects |
Amyl nitrate | · Acute cyanide poisoning with severe symptoms o Altered mental status o Dyspnea, cyanosis o Vomiting, seizures | · Amyl Nitrite: reducing agent that converts hemoglobin to methemoglobin · Sodium Nitrite: reducing agent that converts hemoglobin to methemoglobin · Sodium Thiosulfate: sulfate-forming compound that reacts with cyanide-methemoglobin complex in blood to detoxify the cyanide & allow for excretion in kidneys | Amyl nitrite: do not administer if IV established & able to give sodium nitrite · Sodium thiosulfate: do not administer until after sodium nitrite administered | Adult & pedi: 1 ampule crushed & inhaled | Hypotension - vasodilation |
(Atrovent) Ipratropium Bromide | Bronchospasm that didn’t improve w/ 1st albuterol | Causes bronchodilation and dries secretions | -Sensitivity to atropine -bronchospasm due to allergic reaction | Adult- .5mg in 2.5mL
Pediatric- <1 year- .25mg >1 year- adult dose | -dry mouth -nausea/vomiting |
Aspirin (Acetylsalicylate acid) | Cardiac chest pain | -reduces platelet stickiness
| -aspirin allergy -GI bleed -hemorrhagic stroke | Adult: 324mg
Pediatric: Not given | None in emergency setting |
Ativan (Lorazepam) | Active seizure or status epilepticus Sedation: o To facilitate airway device placement o Maintenance sedative agent o Prior to painful procedure (cardioversion) o Stimulant or hallucinogen ingestion induced chest pain and/or tachycardia o Excited delirium
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Central Nervous System (CNS) Depressant that causes: o Muscle relaxation o Sedation o Amnesia
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· Hypotension Head injury Pregnancy (except eclamptic seizure)
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IV, IM, IN o Adult: 2-10 mg Pedi: 0.05-0.1mg/kg (max. 10 mg)
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Hypotension Respiratory depression Confusion/stupor Nausea Vein irritation, phlebitis, or sclerosis
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TRADE NAME (GENERIC) | INDICATION | HOW IT WORKS | CONTRA- | DOSE | Side effects |
Atropine | -symptomatic bradycardia
-organophosphate poisoning | -reverses vagal tone -blocks acetylcholine in organophosphate poisoning | Hypothermic bradycardias | Adult: Sym Brady- .5mg IV q 3-5 mins (max of 3 mg) Poisoning- 2-5mg q 15mins until secretions stop Pediatric: Sym Brady- .02mg/kg (may repeat once up to max of 1 or 3mg) Poisoning- .05mg/kg | -tachycardia -blurred vision -dry mouth |
Calcium Chloride | -hyperkalemia -hypocalcemia -Magnesium OD -Ca Channel Blocker OD | -helps conduct electrical current in heart
-assists in normal contraction of heart | -cardiac arrest
-hypercalcemia
-digitalis | Adult: 10-15mg/kg
Pediatric: same | Bradycardia and hypotension if too much is pushed too fast
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Calcium Gluconate | -hyperkalemia -Magnesium OD -Ca Channel Blocker OD -black widow bite |
| -cardiac arrest
-hypercalemia | Adult: 15-30mL of 10% solution
Pediatric: 60-100mg/kg slow IV push | -bradycardia -hypercalcemia |
Cardizem (diltiazem)
Calcium Channel Blocker | -Afib or Aflutter w/ RVR
-PSVT unresponsive to adenosine | -Blocks movement of calcium into muscle
-slows rate of ventricular response | Systolic < 90 Diastolic < 60
Wide complex tach
| Adult: 1st .25mg/kg 2nd .35mg/kg IV push over 2 mins
Pediatric: Not used pre hospital | -Bradycardia
-hypotension |
TRADE NAME (GENERIC) | INDICATION | HOW IT WORKS | CONTRA- | DOSE | Side effects |
Decadron (Dexamethasone) | Reduces swelling & inflammation due to: o Refractory bronchospasm in: § Status asthmaticus § Acute exacerbation of Chronic Obstructive Pulmonary | Mechanism of action: · Synthetic adrenal corticosteroids that: o Suppresses immune response o Restores normal capillary permeability o Inhibits the formation, storage, and release of histamine from mast cells · Anti-inflammatory effect in management of: o Allergic reactions and anaphylactic shock o Sometimes used for swelling in spinal cord injury management | Known hypersensitivity | IVP · Adult: 4-24 mg IV/IM Pedi: 0.2- 0.5 mg/kg Not to exceed adult dosage |
May produce hypertension · Rare instances of: o Anaphylactic reactions o Exacerbation of Congestive Heart Failure (CHF) o Seizures |
Dextrose10% | Hypoglycemia |
Increases blood glucose levels | None in hypoglycemia
Use caution w/ head injuries
| Adult: 250ml D10 IV
Pediatric: 5mL/kg of 10% solution | Tissue necrosis w/ infiltration |
Diazepam (Valium) | -active seizure/status epilepticus
-premedication
| Central nervous system depressant
Amnesia, sedation, muscle relaxant | Alcohol or sedative drug use
Head injury | Adult: 5-10mg to max 10mg (IV/IM) Pediatric: .5mg/kg max of 5mg (rectal) .2/kg max 5mg (IV) | Respiratory depression
hypotension |
Diphenhydramine (Benadryl) | -Anaphylaxis -mod/severe allergic reactions (after epi) | Blocks effects of histamine | -MAOIs -newborns and nursing mothers | Adult: 25-50mg Pediatric: 1-2mg/kg | Drowsiness, dizziness, sedation
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Dopamine (Inotropin) | Nonhypovolemic hypotension
Symptomatic bradycardia if atropine ineffective | Low dose-increases perfusion to organs Mod dose-increase rate and force of ventricles High dose-peripheral vasoconstriction | Hypovolemic shock
Tachydysrhythmias
VFib | 2-20mcg/kg/min
effects start at 5-10mcg/kg/min | Hypertension Headache Nausea/vomiting |
TRADE NAME (GENERIC) | INDICATION | HOW IT WORKS | CONTRA- | DOSE | Side effects |
Epi 1:1000 (Adrenalin) | -Asthmatic bronchoconstriction -Allergic/Anaphylaxis -Profound Bradycardia (Atropine, Shock, Dopamine have all failed) | chronotropic effects. o Alpha effects: § Produces peripheral vasoconstriction which: Increases coronary & cerebral perfusion Increases BP in anaphylaxis o Beta-1 effects: § Increases rate, force, & contractility of ventricular contractions o Beta-2 effects: § Bronchodilation
| -Hypersensitivity -Hypovolemic shock -Coronary insufficiency | Adult Asthma/Allergy: 0.3mg SubQIM Bradycardia: 2-10mcg/min Pediatric: .15mg SubQ or IM | -Tachycardia -Hypertension -Can worsen cardiac ischemia
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Epi 1:10000 (Adrenalin) | -Cardiac Arrest -Anaphylaxis | chronotropic effects. o Alpha effects: § Produces peripheral vasoconstriction which: Increases coronary & cerebral perfusion Increases BP in anaphylaxis o Beta-1 effects: § Increases rate, force, & contractility of ventricular contractions o Beta-2 effects: § Bronchodilation
| -Hypersensitivity -Hypovolemic shock -Coronary insufficiency | Adult: CA: 1mg IV q 3-5 min AR: 0.3mg may repeat no more than once Pediatric: CA: .01mg/kg AR: .15mg may repeat no more than once | -Palpitations -anxiety, -Tremulousness -Headache -Dizziness, -Hypertension -Can worsen cardiac ischemia
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TRADE NAME (GENERIC) | INDICATION | HOW IT WORKS | CONTRA- | DOSE | Side effects |
NAME | INDICATION | HOW IT WORKS | CONTRA- INDICATIONS | DOSE | SIDE EFFECTS
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Etomidate | Induction agent before the admin of a Neuromuscular blockade agent | Suppresses CNS activity. | -Known hypersensitivity -Labor/Delivery | 0.3 mg/kg MAX 40mg | -N&V -Dysrhythmias -SOB -Hypotension -Muscle twitch |
Fentanyl | -Pain Control -Sedation for RSI & PAI | Binds w/receptor in brain to produce effects | -Respiratory Depression -Hypotension -N&V | 1-2 mcg/kg to MAX 200mcg | -Respiratory Depression -Bradycardia -Hypo/ Hypertension -N&V |
Oral Glucose | Altered LOC caused by hypoglycemia. | Provides glucose into bloodstream for cellular metabolism | -No gag reflex -Unable to protect airway | 25-50g (full tube) | Aspiration |
Glucagon | -Hypoglycemia (IN or IM) -Beta-blocker OD -Calcium Channel Blocker Toxicity | -Converts stored glycogen in liver to glucose -Improves Cardiac contractility inc. heart rate. | Hypersensitivity to Proteins
| Low sugar: 1mg IM or IN CCB or Beta Blocker OD: 1mg IV/IO up to 3mg Less than age 1 0.5 mg IV/IO/IM/IN/SQ
| -N&V -Tachycardia |
Haldol (Haloperidol) | Patients who require sedation for comfort or safety during transport o Acute psychotic episodes o Severe anxiety and tension o Acute alcohol withdrawal symptoms (Delirium Tremens) | Butyrophenone derivative that inhibits the transport mechanism of cerebral monamines and by blocking dopaminergic neuron receptors in the brain associated with mood and behavior | Preexisting coma Intoxication Known cardiovascular disease
| Adult: 18 y.o.+ 5-10 mg IM Not to exceed 100 mg in 24 hours Pedi: Less than 5 y.o. Not recommended 6 to 12 y.o. 1-3 mg IM Max: 0.15 mg/kg/day 13 to 17 y.o. 2-5 mg IM Not to exceed adult dosage | Extrapyramidal effects aka dystonic reaction o Antidote: Diphenhydramine Benadryl 25-50 mg IVP Tardive dyskinesia Potentially fatal Neuroleptic Malignant Syndrome (NMS) – symptom: fever
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TRADE NAME (GENERIC) | INDICATION | HOW IT WORKS | CONTRA- | DOSE | Side effects |
Heparin | Prevention of thrombus formation in acute MI
| Acts at multiple sites in coagulation process Binds to antithrombin III catalyzing inactivation of thrombin thereby limiting conversion of prothrombin to thrombin and impairing fibrin formation and therefore clot formation
| Active bleeding or bleeding tendencies Recent major surgery or trauma
| IV/ IV Infusion
Adult: 5,000 units IV Follow with 20,000-40,000 units IV over 24 hrs Pedi: 100-150 units/kg IV
Follow with 28 units/kg/hour IV Infusion | Potentially life-threatening bleeding May cause hematologic disorder
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Hydroxocobalamin (Cyanokit®) | Cyanide toxicity | Vitamin B12 molecule complexed to cobalt: cyanide displaces the cobalt on the molecule, resulting in cyanocobalamin, which is then removed from the body by renal excretion |
Absolute: None
Relative: History of anaphylactic reaction to hydroxocobalamin or cyanocobalamin | 5 grams (2 vials) over 15 minutes | Flushing, urticaria, itching or rash Chest tightness and dyspnea Transient blood pressure elevation Anaphylaxis Red skin, tears, sweat and urine |
Ketamine (ketalar) | -Anesthesia prior to RSI -Chemical sedation for Psychiatric/Behavioral issues | Affects catecholaminergic transmission | -Hypersensitivity | RSI: 1mg/kg IV may repeat every 5-10
Sedation: 1mg/kg IV or 4mg/kg IM | -Hypertension -Tachycardia -Sedation -Vomiting -Involuntary muscle movement |
TRADE NAME (GENERIC) | INDICATION | HOW IT WORKS | CONTRA- | DOSE | Side effects |
Labetolol (Trandate or Normodyne) | · Acute hypertensive crisis with End-Organ Dysfunction · Unstable angina · Non Q-wave MI · Abdominal Aortic Aneurysm (AAA) · Supraventricular tachycardia (SVT) with Rapid Ventricular Response (RVR) · Ventricular Tachycardia refractory to Lidocaine | · Competitively blocks beta-adrenergic receptors in heart and blood vessels o Lowers heart rate, cardiac output, and blood pressure o Induces vasodilation o Reduces peripheral vascular resistance o Reduces the rate and force of cardiac contraction · Inhibits the actions of catecholamines · Decreases A-V conduction | Cocaine or amphetamine overdose Congestive Heart Failure (CHF) Hypertension
Antidote: Glucagon Positive inotropic action on heart & decreases renal vascular resistance | · Adult: Hypertensive Crisis: 5-10 mg IV May repeat to total of 20 mg IVP Add 4 mL Labetalol to 6 mL NS Administer 2.5-5 mL of mix, may repeat · Goal: Diastolic BP: 115-130 mmHg Resolve of End-Organ Dysfunction S/S | · Bronchospasm -· Hypotension (AVOID!) – · Hallucinations -· Hyponatremia · Hyperkalemia - |
Lasix (Furosmede) | Acute Pulmonary Edema |
-Diuretic -Osmotic Gradient | -Hypersensitivity -Hypovolemia/ Dehydration | 1mg/kg over 2 min
If Already on Lasix: give twice their daily dose | -Hypotension -Dry mouth -Electrolyte imbalance -if given too fast, can cause hearing loss |
Levophed (Norepinephrine bitartrate) | -Neurogenic & Cardiogenic Shock & Septic Shock -BP<70 (hemodynamically significant. hypotension) | -Vasoconstrictor -Adrenergic Agonist | Hypovolemia | 8-12 mcg/min | -HTN -Dysrhythmias -Angina -Reflex Brady -Tissue Necrosis |
Lidocaine | -Cardiac Arrest from VT / VF -Maintenance Infusion @ ROSC assoc. w/ VT/VF | -Diastolic Depolarization -Supresses PVC’s -Inc. VF threshold | -2nd/3rd heart block -Strokes-Adams syndrome -Prophylactic use in AMI | CA- 1-1.5mg/kg Q 5-10min to MAX 3mg/kg
ROSC- 1-4mg/min | -Light-headed -Confusion -Blurred Vission -Hypotension -Bradycardia -Altered LOC -Seizures |
TRADE NAME (GENERIC) | INDICATION | HOW IT WORKS | CONTRA- | DOSE | Side effects |
Magnesium Sulfate | -Eclamptic Seizure -Ventricular Dysrhythmias -Torsades -Digitoxin Toxicity -Asthma | -CNS Depressant -Physiologic Calcium Channel Blocker | -Heart Block -Myocardial Damage | Eclampsia, Torsades, Asthma: 1-2 g over 10mis
Cardiac Arrest 1-2g IV push | -Diaphoresis -Hypothermia -Respiratory Depression -Facial Flush -Bradycardia -Hypotension -N/V |
Methylprednisolone (Solu-medrol®) | Wheezing refractory to inhaled bronchodilators Status asthmaticus Severe anaphylaxis, in conjunction with epinephrine and diphenhydramine
| Potent anti-inflammatory steroid | Known hypersensitivity to the product and its constituents | 60 – 125 mg IV/IO, if there are no contraindications IM in Asthma Anaphylaxis bp is to low for IM Pedi: 2 mg/kg | May produce hypertension Rare instances of: Anaphylactic reactions Exacerbation of congestive heart failure Seizure |
Midazolam (Versed) | -Active Seizure -Status Epilepticus -Sedation prior to Cardioversion/Pacing | CNS Depressant (amnesia, sedation, relaxation) | -Hypersensitivity -Acute Narrow Angle Glaucoma | 2.5-5mg may repeat once (IV or IN) | -Respiratory Depression -Confusion -Hypotension -Nausea |
Morphine | -Pain & Anxiety -Chest Pain unrelieved by NITRO | -Alleviates Pain -Dec. Anxiety -Vasodilator | -BP <90 -Traumatic Brain Inj. -Respiratory Depression | 2-4 mg q 3-5 mins to hypotension or respiratory depression | -Respiratory depression -Dizziness -N/V -Hypotension -Bradycardia |
Narcan (Naloxone) | Opiate OD | Narcotic Antagonist | Hypersensitivity | 0.4mg to MAX 2mg | -Dysrhythmias -N/V -HTN -Tachycardia -Violent Behavior |
TRADE NAME (GENERIC) | INDICATION | HOW IT WORKS | CONTRA- | DOSE | Side effects |
Nitroglycerin (Nitrostat) | -Chest pain or cardiac origin -Pulmonary Edema assoc. w/ CHF | Vasodilator | -Systolic BP <90 -Increased intracranial pressure -ED drugs -Extreme Brady/Tachycardias | 1 spray 0.4mg 1 SL tablet 0.4mg | -Hypotension -Headache -Reflex Tach -N/V -Diaphoresis |
Nitrous Oxide (Nitronox) | -A&O PT w/pain (Kidney stones, Thermal burns, AMI, Labor, Fractures) | CNS Analgesic/Anesthetic (short term) | -Decompression Sickness -COPD -Chest Trauma -Abd. Distention -Altered LOC | Self Dose | -Hypotension -Dizziness |
Norcuron (Vecuronium) | Long-term muscle paralysis to facilitate endotracheal intubation | Works as competitive antagonist to ACh at post-synaptic receptors in the cholinergic receptor sites at the neuromuscular junction (NMJ). · By blocking/occupying the receptor sites, it prevents stimulation of the muscle without depolarizing the muscle (no fasiculations) leading to muscle paralysis | Hypersensitivity | IV/IO o Adult: 0.1 mg/kg Pedi: 0.1 mg/kg o Onset: 30 sec o Duration: 30-40 min. | · Hypotension or hypertension · Tachycardia or bradycardia · Patients with neuromuscular disease – Multiple Sclerosis · Hepatic or Renal impairment |
TRADE NAME (GENERIC) | INDICATION | HOW IT WORKS | CONTRA- | DOSE | Side effects |
(Pancuronium) Pavulon: | Long-term muscle paralysis to facilitate endotracheal intubation | Works as competitive antagonist to ACh at post-synaptic receptors in the cholinergic receptor sites at the neuromuscular junction (NMJ). · By blocking/occupying the receptor sites, it prevents stimulation of the muscle without depolarizing the muscle (no fasiculations) leading to muscle paralysis | Hypersensitivity | IV/IO o Adult: 0.04 - 0.1 mg/kg Pedi: 0.04-0.1 mg/kg o Onset: 30 sec o Duration: 180 min. | · Hypotension or hypertension · Tachycardia or bradycardia · Patients with neuromuscular disease – Multiple Sclerosis · Hepatic or Renal impairment |
Phenergan (Promethazine) | -Persistent vomiting -GI problems -Allergic Reactions Better than Zofran if Pt. already vomiting | Potent Antiemetic w/sedative effects | -Hypersensitivity -Comatose States -Altered LOC | 12.5mg to max MAX of 25mg | -Drowsiness/ sedation -Dystonic Reaction -Necrosis |
Pralidoxime Chloride (2-PAM®) | •Second drug given for the treatment of poisoning due to organophosphate pesticides and chemical nerve agents (First drug is atropine) •Primary indication for pralidoxime administration is muscle weakness or respiratory depression in these patients | •Reactivates cholinesterase which has been deactivated by chemical nerve agents and organophosphate poisons •Relieves paralysis of the respiratory muscles following chemical nerve agent or organophosphate | Contraindications: No absolute contraindications | 600mg (1 autoinjector) - 1800mg (3 auto-injectors) - standing order | •Tachycardia, laryngospasm, muscle rigidity if IV and infused too quickly •Mild to moderate pain at injection site •Blurred or double vision, dizziness, loss of coordination, headache drowsiness, hypertension, tachycardia |
TRADE NAME (GENERIC) | INDICATION | HOW IT WORKS | CONTRA- | DOSE | Side effects |
Pronestyl (Procainamide) | Suppress ectopy in ventricular tissue & reduce ventricular dysrhythmias such as: o Refractory & recurrent Ventricular Fibrillation (V-Fib) o Pulseless Ventricular Tachycardia (V-Tach) o Stable monomorphic or polymorphic Ventricular Tachycardia w/ pulse o Wide-complex tachydysrhythmias of uncertain type o Malignant, refractory PVCs I-C: Suppress ectopy in atrial tissue & reduce supraventricular dysrhythmias such as: o PACs, PAT, A-Fib, A-Flutter, WPW | · Slows myocardial conduction by stabilizing the myocardial membranes Reduces the automaticity and therefore: o Effectively suppresses a variety of atrial and ventricular dysrhythmias
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· TCA Overdose Previous use of Amiodarone 2nd and 3rd degree heart block
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IV Infusion o 20 – 30 mg/min IV infusion titrate to effect o Max dose: up to 17 mg/kg o Add 1 Gram Procainamide to 250 mL NS, use 10 gtts/min drip set
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· Hypotension 2nd or 3rd degree AV block Widening of the QRS complex
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Racemic epi (Vaponefrin) | · Acute bronchospasm in reactive airway disease such as: o Acute asthma attack o Acute exacerbation of Chronic Obstructive Pulmonary Disease (COPD) o Allergic reaction unresponsive to other treatment o Racemic epinephrine: laryngotracheobronchitis (Croup) | · Activates beta-2 adrenergic receptors in respiratory tract causing relaxation of smooth muscle & bronchodilation
| · Hypersensitivity · Pregnancy – except in life-threatening situation · Racemic epinephrine: Epiglottitis | Inhaled/Nebulized o 0.5 mL of 2.25% soln. in 2.5 mL N.S. every 4 hours prn | Side Effects: · Tachycardia · Restlessness/nervousness/tremors · Hypertension |
TRADE NAME (GENERIC) | INDICATION | HOW IT WORKS | CONTRA- | DOSE | Side effects |
Sodium Bicarbonate | -TCA OD -Hyperkalemia or Acidosis -Prolonged CPR -DKA -Rhabdomyolysis -Compartment Syndrome | Buffers metabolic acidosis | -Alkolosis -PE -Abdominal Pain w/ unknown orgin -Hypocalemia | 1mEq/kg | -Acidosis -Hypoxia -Tissue sloughing -Seizures -Hypernatremia -Inc. PCO2 |
Succinylcholine | To facilitate intubation | Depolarizing neuromuscular blocker | -Burn injuries w/in 12hrs -Inability to control airway -Acute Rhabdomyolysis | Relax: 0.3-1.1mg/kg
RSI: 1-1.5 mg/kg | -Respiratory depression -Bradycardia -Dysrhythmias -Allergic Reaction |
Terbutaline | · Acute bronchospasm in reactive airway disease such as: o Acute asthma attack o Acute exacerbation of Chronic Obstructive Pulmonary Disease (COPD) o Allergic reaction unresponsive to other treatment | · Activates beta-2 adrenergic receptors in respiratory tract causing relaxation of smooth muscle & bronchodilation | · Hypersensitivity · Pregnancy – except in life-threatening situation
| Subcutaneous (SC) o Adult: 0.25 mg SC May repeat once in 15 min if no response o Pedi: 0.01 mg/kg (Not to exceed adult dosage) | · Tachycardia · Restlessness/nervousness/tremors · Hypertension |
Thiamine | Thiamine: vitamin required to convert glucose to energy – must be ingested, body does not manufacture. | Thiamine: vitamin required to convert glucose to energy – must be ingested, body does not manufacture. | A history of sensitivity to thiamine or to any of the ingredients in this drug is a contraindication | IVP/IM o Adult: 50 mg IV/IM May repeat to total of 100 mg |
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Verapamil (calan) | -SVT -Aflutter w/RVR -Afib -Atrial Tach -Unstable angina | Inhibiting the movement of calcium ions across cell membranes. | -Hypersensitivity -Bradycardia | Initial: 2.5-5mg
Repeat: 5-10mg bolus every 15 min
| -Dizziness -Headache -N&V -Hypotension -Bradycardia |
TRADE NAME (GENERIC) | INDICATION | HOW IT WORKS | CONTRA- | DOSE | Side effects |
Zemuron (Rocuronium) | Long-term muscle paralysis to facilitate endotracheal intubation | Works as competitive antagonist to ACh at post-synaptic receptors in the cholinergic receptor sites at the neuromuscular junction (NMJ). · By blocking/occupying the receptor sites, it prevents stimulation of the muscle without depolarizing the muscle (no fasiculations) leading to muscle paralysis | Hypersensitivity | IV/IO o Adult: 1 mg/kg Pedi: 1 mg/kg o Onset: 60-90 sec o Duration: 45-70 min. | · Hypotension or hypertension · Tachycardia or bradycardia · Patients with neuromuscular disease – Multiple Sclerosis · Hepatic or Renal impairment |
Zofran (ondansetron) | Prevention of Nausea Vomiting | Blocks Serotonin Receptor | Hypersensitivity,
Pedi <2yrs of age,
Do Not administer Phenergan & Zofran to same PT. | 2mg to MAX of 4mg
| -Dizziness, -Burning @ injection site, -Drowsiness |