The body contains trillions of cells organized into complex units known as tissues.
Tissues are groups of similar cells and extracellular material (extracellular matrix) that perform a common function such as protection or movement.
Four types of tissues:
Epithelial tissue
Connective tissue
Muscle tissue
Nervous tissue
Cellularity: Made up of tightly packed cells with minimal extracellular matrix.
Locations:
Covers body surfaces
Lines body cavities
Forms glands
Polarity:
Apical surface: exposed to the environment or space.
Basal surface: attached to connective tissue.
Physical Protection: Guards against dehydration, abrasion, and destruction.
Selective Permeability: Controls passage of substances, allowing some to pass while preventing others.
Secretions: Specialized cells secrete substances.
Sensations: Provides information to the nervous system.
By Number of Cell Layers:
Simple epithelium: Single layer, all cells touch the basement membrane.
Stratified epithelium: Multiple layers, offers mechanical stress protection.
Pseudostratified epithelium: Appears stratified but is not.
By Cell Shape:
Squamous: Flattened and irregular.
Cuboidal: Equal height and width.
Columnar: Taller than wide.
Transitional: Changes shape based on stretching.
Glands are composed of epithelial tissue that secretes substances.
Endocrine Glands: Secrete hormones into the bloodstream, no ducts.
Exocrine Glands: Secrete substances onto epithelial surfaces via ducts.
Unicellular: Goblet cells; secrete mucin.
Multicellular: Contain cell clusters (acini) connected to ducts.
Classified by:
Anatomic Form: Simple (single duct) vs Compound (branched ducts).
Method of Secretion: Merocrine (exocytosis), Apocrine (pinch off), Holocrine (ruptured cells).
Most diverse tissue type; has three basic components:
Cells: Resident and wandering cells.
Protein fibers: Collagen, elastic, reticular fibers.
Ground substance: Extracellular matrix that varies in consistency.
Provides physical protection, structural support, binding of structures, storage, transport, and immune protection.
Loose CT: Fewer cells and fibers; includes areolar, adipose, reticular.
Dense CT: Fewer ground substance but more fibers; includes dense regular, dense irregular, elastic.
Cartilage: Firm, semisolid matrix with chondrocytes in lacunae; includes hyaline, fibrocartilage, elastic cartilage.
Bone: Solid matrix; includes compact and spongy bone with osteocytes.
Blood: Consists of formed elements (red/white blood cells, platelets) in plasma.
Lymph: Derived from blood plasma containing no cellular components.
Muscle tissues are responsible for movement; three types:
Skeletal Muscle: Voluntary, striated, multinucleated.
Cardiac Muscle: Involuntary, striated, branched, found in the heart.
Smooth Muscle: Involuntary, non-striated, found in walls of hollow organs.
Composed of neurons (transmit impulses) and glial cells (supporting cells).
Neurons receive, process, and transmit nerve impulses.
Composed of two or more tissue types working together.
Example: The stomach contains all four tissues (epithelium, connective, muscle, nervous).
Tissues develop from embryonic germ layers (ectoderm, mesoderm, endoderm).
Aging affects all tissues; results in reduced efficiency and changes in structural properties.