Comprehensive Study Guide for Prescription Abbreviations and Laboratory Reference Ranges
Common Prescription Abbreviations
Laboratory Reference Ranges Guidance
- Clinical Testing Variability:
- Laboratory reference ranges provide expected baseline values for analyzing client laboratory results.
- Accuracy in laboratory testing has evolved; however, variability in reference ranges can occur between individual laboratories based on the specific testing methods utilized.
- When providing client care, clinicians must refer directly to the reference ranges provided by the specific reporting laboratory.
Complete Blood Count (CBC)
Hematocrit [Hct] (Unit: %):
- Age 2\,weeks to 2\,months: 39% to 59%
- Age 2\,months to 6\,months: 35% to 50%
- Age 6\,months to 1\,year: 29% to 43%
- Age 1\,year to 6\,years: 30% to 40%
- Age 6\,years to 18\,years: 32% to 44%
- Greater than 18\,years:
- Female: 37% to 47%
- Male: 42% to 52%
- Pregnant female: Greater than 33%
- CRITICAL VALUE: Less than 21% or greater than 65%
Hemoglobin [Hgb] (Unit: g/dL):
- Age 2\,months to 6\,months: 10 to 17g/dL
- Age 6\,months to 6\,years: 9.5 to 14g/dL
- Age 6\,years to 18\,years: 10 to 15.5g/dL
- Greater than 18\,years:
- Female: 12 to 16g/dL
- Male: 14 to 18g/dL
- CRITICAL VALUE: Less than 7g/dL or greater than 21g/dL
Platelet Count (Unit: /mm3):
- Infant: 200,000 to 475,000/mm3
- Child and Adult: 150,000 to 400,000/mm3
- CRITICAL VALUE: Less than 20,000/mm3 or greater than 1,000,000/mm3
Mean Platelet Volume (Unit: fL [femtoliter]):
- Reference range: 7.4 to 10.4fL
Red Blood Cell Count [RBC] (Unit: ×106/μL):
- Age 2\,weeks to 2\,months: 3.5×106/μL to 5.5×106/μL
- Age 2\,months to 6\,months: 3.5×106/μL to 5.5×106/μL
- Age 6\,months to 1\,year: 3.5×106/μL to 5.2×106/μL
- Age 1\,year to 18\,years: 4×106/μL to 5.5×106/μL
- Greater than 18\,years:
- Female: 4.2×106/μL to 5.4×106/μL
- Male: 4.7×106/μL to 6.1×106/μL
Red Blood Cell Indices:
- Mean Corpuscular Volume [MCV] (Unit: fL):
- Newborn: 96 to 108fL
- Child/Adult/Older adult: 80 to 95fL
- Mean Corpuscular Hemoglobin [MCH] (Unit: pg):
- Newborn: 32 to 34pg
- Child/Adult/Older adult: 27 to 31pg
- Mean Corpuscular Hemoglobin Concentration [MCHC] (Unit: g/dL):
- Newborn: 32 to 33g/dL
- Child/Adult/Older adult: 32 to 36g/dL
- Red Blood Cell Distribution [RDW] (Unit: %):
- Adult: Variation of 11% to 45%
White Blood Cell Count [WBC] [Total] (Unit: /mm3):
- Age 1\,month to 24\,months: 6,200 to 17,000/mm3
- Child and Adult: 5,000 to 10,000/mm3
- CRITICAL VALUE: Less than 2,000/mm3 or greater than 40,000/mm3
WBC Differential:
- Neutrophils: 55% to 70%; Absolute count: 2,500 to 8,000/mm3
- Lymphocytes: 20% to 40%; Absolute count: 1,000 to 4,000/mm3
- Monocytes: 2% to 8%; Absolute count: 100 to 700/mm3
- Eosinophils: 1% to 4%; Absolute count: 50 to 500/mm3
- Basophils: 0.5% to 1%; Absolute count: 25 to 100/mm3
Alanine Aminotransferase [ALT] (Unit: international units/L):
- Child/Adult: 4 to 36international units/L
Albumin and Total Protein (Unit: g/dL):
- Albumin: 3.5 to 5g/dL
- Total Protein: 6.4 to 8.3g/dL
Alkaline Phosphatase [ALP] (Unit: units/L):
- Birth to 2\,years: 85 to 235units/L
- Age 2\,to 8\,years: 65 to 210units/L
- Age 9\,to 15\,years: 60 to 300units/L
- Age 16\,to 21\,years: 30 to 200units/L
- Adults: 30 to 120units/L
Aspartate Aminotransferase [AST] (Unit: units/L):
- Age 0\,to 5\,days: 35 to 140units/L
- Less than 3\,years: 15 to 60units/L
- Age 3\,to 6\,years: 15 to 50units/L
- Age 6\,to 12\,years: 10 to 50units/L
- Age 12\,to 18\,years: 10 to 40units/L
- Adults: 0 to 35units/L
Bicarbonate [HCO3] / Carbon Dioxide Content (Unit: mEq/L):
- Newborn: 13 to 22mEq/L
- Infant: 20 to 28mEq/L
- Child: 20 to 28mEq/L
- Adult: 23 to 30mEq/L
Bilirubin (Unit: mg/dL):
- Total Bilirubin:
- Newborn: 1 to 12mg/dL
- Child/Adult: 0.3 to 1mg/dL
- Direct Bilirubin:
- Child/Adult: 0.1 to 0.3mg/dL
- Indirect Bilirubin:
- Child/Adult: 0.2 to 0.8mg/dL
Blood Urea Nitrogen [BUN] (Unit: mg/dL):
- Infant: 5 to 18mg/dL
- Child: 5 to 18mg/dL
- Adult: 10 to 20mg/dL
- CRITICAL VALUE: Greater than 100mg/dL
Calcium (Total) (Unit: mg/dL):
- Less than 10\,days: 7.6 to 10.4mg/dL
- Age 10\,days to 2\,years: 9.0 to 10.6mg/dL
- Child: 8.8 to 10.8mg/dL
- Adult: 9.0 to 10.5mg/dL
- CRITICAL VALUE: Less than 6mg/dL or greater than 13mg/dL
Chloride [Cl] (Unit: mEq/L):
- Infant: 96 to 106mEq/L
- Child: 90 to 110mEq/L
- Adult: 98 to 106mEq/L
Creatinine (Unit: mg/dL):
- Less than 2\,years of age: 0.1 to 0.4mg/dL
- Age 2\,years to less than 6\,years: 0.2 to 0.5mg/dL
- Age 6\,years to less than 10\,years: 0.3 to 0.6mg/dL
- Age 10\,years to less than 18\,years: 0.4 to 1mg/dL
- Age 18\,years to less than 41\,years:
- Female: 0.5 to 1mg/dL
- Male: 0.6 to 1.2mg/dL
- Age 41\,years to less than 61\,years:
- Female: 0.5 to 1.1mg/dL
- Male: 0.6 to 1.3mg/dL
- Age 60\,years and older:
- Female: 0.5 to 1.2mg/dL
- Male: 0.7 to 1.3mg/dL
- CRITICAL VALUE: Greater than 4mg/dL
Glucose (Unit: mg/dL):
- Infant: 40 to 90mg/dL
- CRITICAL VALUE: Less than 40mg/dL
- Age 13\,months to 2\,years: 60 to 100mg/dL
- Child greater than 2\,years: 70 to 110mg/dL
- Adult: 74 to 106mg/dL
- CRITICAL VALUE (Male): Less than 50mg/dL or greater than 450mg/dL
- CRITICAL VALUE (Female): Less than 40mg/dL or greater than 450mg/dL
Magnesium [Mg] (Unit: mEq/L):
- Newborn: 1.4 to 2mEq/L
- Child: 1.4 to 1.7mEq/L
- Adult: 1.3 to 2.1mEq/L
- CRITICAL VALUE: Less than 0.5mEq/L or greater than 3mEq/L
Potassium [K] (Unit: mEq/L):
- Infant: 4.1 to 5.3mEq/L
- Child: 3.4 to 4.7mEq/L
- Adult: 3.5 to 5mEq/L
- CRITICAL VALUE: Less than 3mEq/L or greater than 8mEq/L
Sodium [Na] (Unit: mEq/L):
- Infant: 134 to 150mEq/L
- Child: 136 to 145mEq/L
- Adult: 136 to 145mEq/L
- CRITICAL VALUE: Less than 120mEq/L or greater than 160mEq/L
Arterial Blood Gases (ABGs)
pH:
- Newborn: 7.32 to 7.49
- Age 2\,months to 24\,months: 7.34 to 7.46
- Child/Adult: 7.35 to 7.45
- CRITICAL VALUE: Less than 7.25 or greater than 7.6
- Venous pH: 7.31 to 7.41
PCO2 (Unit: mmHg):
- Child under 24\,months: 26 to 41mmHg
- Child/Adult: 35 to 45mmHg
- CRITICAL VALUE: Less than 20mmHg or greater than 60mmHg
HCO3 (Unit: mEq/L):
- Newborn/Infant: 16 to 24mEq/L
- Child/Adult: 22 to 26mEq/L
- CRITICAL VALUE: Less than 10mEq/L or greater than 40mEq/L
PO2 (Unit: mmHg):
- Newborn: 60 to 70mmHg
- Child/Adult: 80 to 100mmHg
- CRITICAL VALUE: Less than 40mmHg
- Venous PO2: 40 to 50mmHg
O2 Saturation (Unit: %):
- Newborn: 40% to 90%
- Child/Adult: 95% to 100%
- CRITICAL VALUE: 75% or less
- Older Adult: 95%
O2 Content (Unit: volume%):
- Arterial: 15% to 22%
- Venous: 11% to 16%
Base Excess (Unit: mEq/L):
- Expected Range: 0±2mEq/L
- CRITICAL VALUE: ±3mEq/L
Alveolar to Arterial O2 Difference (Unit: mmHg):
- Expected Range: Less than 10mmHg
Additional Serum Laboratory Tests
Coagulation Profile:
- Activated Partial Thromboplastin Time (aPTT): 30 to 40seconds
- CRITICAL VALUE: Greater than 70seconds
- Partial Thromboplastin Time (PTT): 60 to 70seconds
- CRITICAL VALUE: Greater than 100seconds
- Prothrombin Time [PT]: 11 to 12.5seconds
- Full anticoagulant therapy: Greater than 1.5 to 2times the control value
- CRITICAL VALUE: Greater than 20seconds
- International Normalized Ratio [INR]: 0.8 to 1.1
- CRITICAL VALUE: Greater than 5
Cardiac and Inflammatory Biomarkers:
- Brain Natriuretic Peptides [BNP]: Less than 100ng/L
- CRITICAL VALUE: Greater than 400ng/L
- C-Reactive Protein [CRP]: Less than 1mg/dL
- Risk stratification for cardiac risk factors:
- Low Risk: Less than 1mg/dL
- Average Risk: 1 to 3mg/dL
- High Risk: Greater than 3mg/dL
Glycosylated Hemoglobin [HbA1c] (Unit: %):
- Clients without diabetes: 4% to 5.9%
- Clients with diabetes:
- Good control: Less than 7%
- Fair control: 8% to 9%
- Poor control: Greater than 9%
Lipoproteins (Unit: mg/dL):
- High Density Lipoprotein [HDL]:
- Female baseline: Greater than 55mg/dL
- Male baseline: Greater than 45mg/dL
- For clients with cardiac risk factors:
- Low Risk: Female 70mg/dL, Male 60mg/dL
- Moderate Risk: Female 55mg/dL, Male 45mg/dL
- High Risk: Female 35mg/dL, Male 25mg/dL
- Low Density Lipoprotein [LDL]:
- Children: Less than 110mg/dL
- Adults: Less than 130mg/dL
- Very Low Density Lipoprotein [VLDL]: 7 to 32mg/dL
Urinalysis Reference Ranges
Physical Properties:
- Appearance: Clear
- Color: Amber Yellow
- Odor: Aromatic
- Specific Gravity: 1.005 to 1.03
Chemical Properties:
- pH: 4.6 to 8
- Protein:
- Random specimen: 0 to 8mg/dL
- 24\,hour specimen (at rest): 50 to 80mg/24hr
- 24\,hour specimen (during exercise): Less than 250mg/24hr
- Leukocyte Esterase: Negative
- Nitrites: None
- Ketones: None
- Bilirubin: None
- Urobilinogen: 0.01 to 1Ehrlich unit/mL
- Glucose:
- Fresh specimen: None
- 24\,hour specimen: 50 to 300mg/24hr
Microscopic Examination:
- Crystals: None
- Casts: None
- White Blood Cells [WBC]: 0 to 4per low-power field
- Red Blood Cells [RBC]: Less than or equal to 2
Therapeutic Medication Monitoring
Acetaminophen:
- Therapeutic Level: Depends on use
- Toxic Level: Greater than 25mcg/mL
- Peak Concentration Time: Not specified
Amikacin:
- Therapeutic Level: 15 to 25mcg/mL
- Toxic Level: Greater than 250mcg/mL
- Peak Concentration Time: Not specified
Aminophylline:
- Therapeutic Level: 10 to 20mcg/mL
- Toxic Level: Greater than 20mcg/mL
- Peak Concentration Time: Not specified
Amitriptyline:
- Therapeutic Level: 120 to 150ng/mL
- Toxic Level: Greater than 500ng/mL
- Peak Concentration Time: Not specified
Carbamazepine:
- Therapeutic Level: 5 to 12mcg/mL
- Toxic Level: Greater than 12mcg/mL
- Peak Concentration Time: Not specified
Cyclosporine:
- Therapeutic Level: 100 to 400ng/mL
- Toxic Level: Greater than 400ng/mL
- Peak Concentration Time: Not specified
Chloramphenicol:
- Therapeutic Level: 10 to 20mcg/mL
- Toxic Level: Greater than 25mcg/mL
- Peak Concentration Time: Not specified
Desipramine:
- Therapeutic Level: 150 to 300ng/mL
- Toxic Level: Greater than 500ng/mL
- Peak Concentration Time: Not specified
Digitoxin:
- Therapeutic Level: 15 to 25ng/mL
- Toxic Level: Greater than 25ng/mL
- Peak Concentration Time: Not specified
Digoxin:
- Therapeutic Level: 0.8 to 2ng/mL
- Toxic Level: Greater than 2.4ng/mL
- Peak Concentration Time: 30 to 90min
Disopyramide:
- Therapeutic Level: 2 to 5mcg/mL
- Toxic Level: Greater than 5mcg/mL
- Peak Concentration Time: Not specified
Ethosuximide:
- Therapeutic Level: 40 to 100mcg/mL
- Toxic Level: Greater than 100mcg/mL
- Peak Concentration Time: Not specified
Gentamicin:
- Therapeutic Level: 5 to 10mcg/mL
- Toxic Level: Greater than 12mcg/mL
- Peak Concentration Time: 30min
Imipramine:
- Therapeutic Level: 150 to 300ng/mL
- Toxic Level: Greater than 500ng/mL
- Peak Concentration Time: Not specified
Kanamycin:
- Therapeutic Level: 20 to 25mcg/mL
- Toxic Level: Greater than 35mcg/mL
- Peak Concentration Time: Not specified
Lidocaine:
- Therapeutic Level: 1.5 to 5mcg/mL
- Toxic Level: Greater than 5mcg/mL
- Peak Concentration Time: 2hr
Lithium:
- Therapeutic Level (Acute Mania): 0.8 to 1.2mEq/L
- Therapeutic Level (Maintenance): 0.5 to <1.5mEq/L
- Toxic Level: 1.5mEq/L
- Peak Concentration Time: 1 to 3hr
Methotrexate:
- Therapeutic Level: Greater than 0.01μmol
- Toxic Level: Greater than 10μmol/24 hr
- Peak Concentration Time: Not specified
Nortriptyline:
- Therapeutic Level: 50 to 150ng/mL
- Toxic Level: Greater than 500ng/mL
- Peak Concentration Time: Not specified
Phenobarbital:
- Therapeutic Level: 10 to 30mcg/mL
- Toxic Level: Greater than 40mcg/mL
- Peak Concentration Time: 12hr
Phenytoin:
- Therapeutic Level: 10 to 20mcg/mL
- Toxic Level: Greater than 30mcg/mL
- Peak Concentration Time: 4 to 8hr
Primidone:
- Therapeutic Level: 5 to 12mcg/mL
- Toxic Level: Greater than 15mcg/mL
- Peak Concentration Time: Not specified
Procainamide:
- Therapeutic Level: 4 to 10mcg/mL
- Toxic Level: Greater than 16mcg/mL
- Peak Concentration Time: 1 to 2hr
Propranolol:
- Therapeutic Level: 50 to 100ng/mL
- Toxic Level: Greater than 150ng/mL
- Peak Concentration Time: Not specified
Quinidine:
- Therapeutic Level: 2 to 5mcg/mL
- Toxic Level: Greater than 10mcg/mL
- Peak Concentration Time: 2hr
Salicylate:
- Therapeutic Level: 100 to 250mcg/mL
- Toxic Level: Greater than 300mcg/mL
- Peak Concentration Time: Not specified
Sirolimus:
- Therapeutic Level: 3 to 20ng/mL
- Toxic Level: Greater than 20ng/mL
- Peak Concentration Time: Not specified
Tacrolimus:
- Therapeutic Level: 5 to 15ng/mL
- Toxic Level: Greater than 20ng/mL
- Peak Concentration Time: Not specified
Theophylline:
- Therapeutic Level: 10 to 20mcg/mL
- Toxic Level: Greater than 20mcg/mL
- Peak Concentration Time: 2 to 3hr
Tobramycin:
- Therapeutic Level: 5 to 10mcg/mL
- Toxic Level: Greater than 12mcg/mL
- Peak Concentration Time: Not specified
Valproic Acid:
- Therapeutic Level: 50 to 100mcg/mL
- Toxic Level: Greater than 100mcg/mL
- Peak Concentration Time: Not specified