Detailed Veterinary Neurology Study Notes

Neoplasia Review

  • Recap of neoplasia completed, referencing slide 11.

Seizure Activity Phases

  • Three Phases of Seizure Activity: Preictal, Ictal, Postictal
    • Preictal Phase: Duration ranges from seconds to hours before a seizure starts.
    • Ictal Phase: The phase during which the seizure occurs.
    • Postictal Phase: The recovery period after the seizure ends. Duration and effects vary.

Antiepileptic Therapy Initiation Criteria

  • Criteria for Initiating Antiepileptic Drug (AED) Therapy:
    • Duration of seizure activity greater than three to five minutes (e.g. grand mal seizure).
    • Defined as "cluster seizures" if the patient experiences more than three seizures in 30 days.
    • Consider patients over seven years old having repeated seizures as high risk for therapy initiation.

Types of Myoclonus

  • Three Types of Myoclonus:
    • Side to side myoclonus
    • Up and down myoclonus
    • Rotary myoclonus (referred to as "revolting" cycle)

Nystagmus

  • Fast Phase of Nystagmus: Defined as the quick corrective phase of eye movement.
  • Vestibular Treatment for Nystagmus: Common treatments include medications such as antihistamines (e.g., Meclizine) for motion sickness. High levels of disturbance may lead to options such as euthanasia in severe cases.
  • Idiopathic Vestibular Disease: Typically resolves within one week.
  • Epley Maneuver: A repositioning maneuver for treatment of certain types of vertigo or vestibular disease, beneficial for dogs and some humans. Recommended for cases reported as idiopathic.

Spinal Cord Injuries and Effects

  • Types of Spinal Cord Injuries:
    • Acute rupture or trauma can lead to immediate pain, paresis, or paralysis.
    • Paresis vs. Paralysis:
    • Paresis: Partial weakness
    • Paralysis: Complete lack of movement or feeling.
  • Prevention Strategies:
    • Core strengthening exercises and client education on limiting stress on the spine (e.g. preventing dachshunds from jumping).
    • Exercise regimens focused on abdominal and lower back muscle strengthening.

Clinical Signs and Prognosis

  • Neurological Clinical Signs: Pain, paresis, paralysis, changes in bladder function.
  • Deep Pain Sensation: Absence of deep pain often indicates a worse prognosis for regaining function.
  • Client Education on Bladder Maintenance: Critical for managing lower motor neuron lesions to prevent rupture and urinary retention, which may damage kidneys and increase UTI risk.

Diagnostic Techniques for Spinal Disc Disease

  • Disk Anatomy and Mechanics: Herniated disks apply pressure on the spinal cord and nerves, leading to significant functional impairment.
  • Diagnostic Techniques:
    • Myelogram: Use of radiopaque dye to visualize spinal cord compression through radiographic imaging.
    • X-rays: Can show compression but are not conclusive, further requiring MRI for accurate diagnosis.

Specific Conditions and Their Management

  • Degenerative Myelopathy (DM): Inherited condition seen primarily in German Shepherds and similar breeds. Symptoms include progressive hind end weakness and potential paralysis.
    • Management Options: Supportive care through exercise, physical therapy, and in some trials, amino acid supplements are currently in discussion.

Clinical Conditions Leading to Paraplegia

  • Notable Conditions Associated with Paraplegia:
    • Wobblers syndrome: Common in Dobermans and Great Danes. Requires surgical intervention in severe cases.
    • Euthanasia Considerations: When managing chronic neurological diseases, owners must consider quality of life and treatment costs versus benefits.

Neurological Assessments

  • Neurological Evaluations: Involves recognizing various reflexes; when pinching the tail, dogs often initiate motor functions even when paralyzed.
  • Assisted Mobility: Use of harnesses that alleviate pressure on limbs during accidental falls.
    • Simple exercises are recommended for strengthening and promoting mobility recovery, focusing on proprioception and joint stability.

Final Learning and Management Strategies

  • Owner Involvement: Essential for rehabilitation success. Dietary management, exercise routines, and scheduled vet visits are vital.
  • Emotional Support for Owners: Training in familiar signs of distress or deterioration in their dogs is crucial for making informed treatment decisions.