Pulmonary Edema in Poisoning

Pulmonary Edema in Poisoning (EG)

Mechanism of Occurrence (IPCP)

  • Caused primarily by inhalation (IH) of irritants leading to pulmonary epithelium injury, followed by exudation into the alveoli.

  • Ingestion, injection, or skin absorption (IG-IJ-SA) of parasympathetic stimulants or cholinesterase inhibitors (phosphate esters) stimulate increased bronchial secretion, resulting in pulmonary edema.

Consequences (OD)

  • Interferes with oxygen exchange in the lungs.

  • Can lead to drowning in own secretions.

Emergency Measures (MOPA)

  1. Relieve anxiety with Morphine sulfate (10 mg).

  2. Administer 40% oxygen via face mask.

  3. Use an intermittent positive-pressure oxygen resuscitator (IPPOR) for short periods.

  4. Administer aminophylline (0.5 g IV) to alleviate bronchial constriction.

General Measures (D-EA/SF)

  • Diuresis with Ethacrynic acid (Edecrin, 25 mg orally or IV).

  • Position the patient in semi-fowler (30-45°) or sitting position to aid anxiety relief.