Lipids

  • Lipids are ==hydrophobic== (“water-fearing”), or insoluble in water, bc they are ==non-polar molecules==
  • Like carbohydrates, lipids contain carbon, hydrogen, and oxygen, but in lipids, the proportion of oxygen is much smaller
  • They are the body’s main form of stored energy, plasma membranes, and hormones
  • They also include fats, phospholipids, steroids, and waxes
Biological Roles of Lipids

Shock Absorbant

  • Fat absorbs shocks
  • Organs that are prone to bumps and shocks are ==cushioned== w a relatively ==thick layer== of fat

Metabolic Water

  • Lipids are a source of ==metabolic water==
  • During respiration, stored lipids are ==metabolized for energy==, producing water, and CO2

Insulation

  • Stored lipids provide ==insulation== in extreme environment
  • Increased body fat levels in winter ==reduce heat losses== to the environment
Most Common Fat
  • Fat molecules are also called ==triacylgycerols or triglycerides==
  • They are made up of a ==glycerol backbone + three fatty acid tails==
  • In the human body, triglycerides are primarily stored in ==specialized fat cells called adipocytes== (adipose tissue)

 

Glycerol
  • An organic compound w three carbon atoms, five hydrogen atoms, and three hydroxyl (OH-) groups

   

Fatty Acids
  • Have a ==long chain of hydrocarbons== to which an ==acidic carboxyl group is attached==
Triglyceride Formation
  • Glycerides are formed when the hydroxyl group on glycerol ==bonds== w the carboxyl group (COOH) on fatty acids (dehydration synthesis)
  • Bond is called ==ester linkage==, and the process is known as ==esterification== (a C-O-C bond)

 

Saturated
  • Saturated fatty acids contain as much hydrogen as it possibly could, bc there is a ==single bond betwen all its carbon atom==s (therefore ==two hydrogens== can form in each)
    • ==Solid at room temp==
Unsaturated - monounsaturated
  • Fatty acids w ==one or more double bonds== are unsaturated since they contain ==less hydrogen== than before
  • Monounsaturated fatty acids contain ==one double bond==, meaning a hydrogen was ==taken away== from it
  • These double bonds result in kinks in the fatty acid chain affecting the ==melting point== of the fact
Unsaturated - polyunsaturated
  • Contains ==more than one double bond==, further depriving it of hydrogens
    • Tends to be ==liquid at room temp== as double bonds cause kinks in the structure and prevent molecules from packing together
  • A type of dietary fat, and one of the healthy ones (w monounsaturated)
  • Found in ==plant and animal foods==, like salmon, vegetable oils, and some nuts and seeds
Hydrogenation
  • Hydrogen atoms are ==added to double bonds== in unsaturated triacylglycerols
  • Forms trans form rather than the cis form

 

Trans Fat vs Cis Fat
  • In cis, chains of carbon atoms are on the ==same side of the double bond==, resulting in a kink
  • In trans, hydrogen atoms are on the ==opposite side of the double bonds== of the carbon chain, making the fat molecule straight
  • Cis isomers cannot line up next to one another as the trans isomers due to the ==larger bend==

 

Phospholipids
  • Make up the ==lipid bilayer== of cell membranes, and ==important structural feature== of cells
  • Made up of a glycerol + two hydrophobic fatty acids + hydrophilic phosphate group

Phospholipids Bilayer

  • Phosphate heads facing the water and their tails pointing towards the inside
  • Bilayer prevents hydrophilic tails from coming into contact w water
  • If a drop of phospholipids is placed in water, it may spontaneously form a sphere-shaped structure known as a ==micelle==
    • Hydrophilic phosphate heads ==face the outside== and the fatty acids tails ==face the interior== of this structure
  • This formation is a response to the ==amphipathic nature== of fatty acids

 

Steroids
  • A lipid composed of ==four carbon ring + OH functional group==
  • Also called sterols due to ==hydroxyl group== on ==one or more rings==
  • Do not contain any fatty acids
  • Considered lipids bc they are ==hydrophobic and insoluble in water==

 

Cholestrol
  • A steroid that is essential for animal cell membranes and converts into a number of compounds, like vitamin D
  • High cholestrol levels contribute to ==atherosclerosis==, which can lead to heart attacks and strokes
Waxes
  • Fatty acids linked to ==alcohols or carbon rings==
  • Non-polar - hydrophobic
  • Pliable consistency - ==forms waterproof coating==
  • Barrier against ==water loss and infection==
  • Keeps birds dry and bees busy (forms honeycombs/beeswax)
  • Waxes cover the feathers of some aquatic birds and the leaf surfaces of some plants
    • Hydrophobic properties prevent water from ==sticking to or soaking into the surface==