Monosaccharide Transport Mechanisms

Enterocyte Entry Mechanisms

Glucose and Galactose Entry

• Transporter: SGLT1 (Sodium-Glucose Linked Transporter 1)
• Transport Type: Secondary Active Transport
• Mechanism: Moves glucose and galactose against their concentration gradient.
• Coupling: This movement is coupled with the cotransport of 2 sodium (Na+) ions.
• Note: The mechanism is identical for both glucose and galactose.

Fructose Entry

• Transporter: GLUT5 (Glucose Transporter Type 5)
• Transport Type: Facilitated Diffusion
• Mechanism: Moves fructose down its concentration gradient.
• Note: This transport mechanism is Na-independent.

Exit from Enterocyte into Capillary Blood

Glucose, Galactose, and Fructose Exit

• Transporter: GLUT2 (Glucose Transporter Type 2)
• Transport Type: Facilitated Diffusion
• Mechanism: Transports all three monosaccharides (glucose, galactose, and fructose) down their concentration gradient.
• Destination: From the enterocyte (intestinal absorptive cell) into the interstitial fluid (ISF) and subsequently into the capillary blood.
• Note: This is a Na-independent process.