Effects of Increased Glucose Concentration in Blood

Effects of Increased Glucose Concentration in Blood (OVINW)

1. Osmotic Effects

• Diuresis (Polyuria): Leads to reduced circulating volume.

  • Resulting in thirst and polydipsia.

2. Vision Impairment

• Changes in refractive index of high glucose solution in the eye.

  • Causes blurred vision.

3. Risk of Infections

• Presence of glycosuria (excretion of glucose into the urine) increases risk of Candida infections, especially in women.

4. Nutritional Consequences

• Loss of Calories: Calories are lost in urine.

  • Inability to store energy as glycogen or fat.

  • Impaired protein storage in muscle tissue.

5. Weight and Muscle Changes

• Common to experience weight loss.

• Associated with loss of fat and muscle ('amyotrophy').