Upper Digestive Tract
Overview of the Digestive System
Purpose: Prepare nutrients for absorption by the body, which can then be utilized by cells.
Digestion: The process of altering physical and chemical composition of food for absorption.
Digestive Tract and Accessory Organs
Main Organs of Upper Digestive Tract:
Mouth
Pharynx (throat)
Esophagus
Stomach
Lower Digestive Tract:
Small intestine (duodenum, jejunum, ileum)
Large intestine (cecum, colon, rectum, anal canal)
Accessory Organs:
Liver
Pancreas
Salivary glands
Gallbladder
Digestive Processes
Types of Secretion:
Endocrine: Hormones released into the bloodstream.
Exocrine: Secretions that travel through ducts, e.g., saliva and pancreatic enzymes.
Movement: Regulated peristalsis and segmentation to process food efficiently.
Physical and Chemical Digestion
Physical Digestion: Breaking food into smaller pieces (e.g., teeth grinding).
Chemical Digestion: Involves enzymes and acids that alter food chemically (e.g., saliva, stomach acid).
Structure of the GI Tract
Four layers of tissue in the GI tract:
Mucosal layer (innermost)
Submucosal layer
Muscular layer
Serosa (outermost)
Muscular Layers: Typically two layers (circular and longitudinal) except in the stomach, which has an additional layer for mixing.
Oral Cavity Structures
Key Structures:
Lips
Cheeks
Tongue: Involved in chewing and swallowing, anchored by the lingual frenulum
Tonsils and epiglottis (related to swallowing)
Salivary Glands:
Parotid: Largest, watery saliva with enzymes.
Submandibular: Enzymes and mucus.
Sublingual: Mucusy saliva.
Teeth Structure
Types of Teeth:
20 baby teeth vs. 32 adult teeth
Central incisors, lateral incisors, canines, premolars, molars.
Tooth Numbering: 1 (upper wisdom tooth) to 32 (lower wisdom tooth).
Tooth Anatomy:
Pulp (core with nerves)
Dentin (hard tissue)
Cementum (connects tooth to jawbone)
Enamel (hardest substance in the body)
Food Movement Pathway
Deglutition: Act of swallowing food (bolus) from mouth through pharynx to esophagus.
Esophagus Length: About 10 inches with upper esophageal sphincter (UES) preventing air entry and lower esophageal sphincter (cardiac sphincter) controlling acid reflux.
Stomach Functionality
Sections: Fundus, body, pylorus; contains rugae for expansion.
Muscular Layers: Three directions for mixing (longitudinal, circular, oblique).
Functions: Food reservoir, liquefaction of food (chyme), secrete gastric juices, minimal absorption (some drugs, alcohol).
Cells in Gastric Glands:
Chief cells (secrete pepsin)
Parietal cells (secrete HCl and intrinsic factor)
Endocrine cells (secrete gastrin and ghrelin).
Important Digestive Terms
Chyme: Liquefied food mixture in the stomach.
Rugae: Folds in the stomach allowing expansion.
Gastric Juices: Help digest food and protect against microorganisms.