Acute Poststreptococcal Glomerulonephritis (AGN) | sudden onset of fever, edema around the eyes, fatigue and hypertension | oliguria | hematuria, proteinuria increased BUN | RBC casts, dysmorphic RBCs, hyaline and granular casts and WBCs |
Rapidly Progressive (Crescentic) Glomerulonephritis (RPGN) | progression of AGN, renal failure | oliguria | hematuria, proteinuria, increased BUN, fibrin degradation products, cryoglobulins and IgA immune complexes | RBC casts, dysmorphic RBCs, hyaline and granular casts and WBCs |
Goodpasture syndrome | hemoptysis (spitting out blood from lungs) and dyspnea (shortness of breath) | | hematuria, proteinuria, presence of antiglomerular basement membrane antibodies in blood serum | RBC casts |
Wegener’s Granulomatosis | pulmonary symptoms, granulomas in the small blood vessels of the kidney and respiratory system | | hematuria, proteinuria, presence of antineutrophilic cytoplasmic antibody (ANCA) in the blood serum, elevated serum creatinine and BUN | RBC casts |
Henoch-Schönlein Pupura | raised red patches on the skin, blood in the sputum and stools, progression to glomerulonephritis and renal failure | | mild to heavy proteinuria and hematuria | RBC casts |
Membranous Glomerulonephritis | nephrotic syndrome symptoms and thrombosis, slow progression with possible remission | | microscopic hematuria and proteinuria | |
Membranoproliferative Glomerulonephritis | autoimmune disorders, infections and malignancies. | | hematuria and proteinuria, decreased blood serum complement levels | |
Immunogloblin A Nephropathy/Berger Disease | progression of glomerular disorders, fatigue, anemia, hypertension and edema | oliguria | macroscopic hematuria, proteinuria, glucosuria, markedly decreased glomerular filtration rate, increased BUN and creatinine, electrolyte imbalance, increased serum IgA levels | many varieties of casts including broad casts |
Nephrotic Syndrome | pronounced edema | | massive proteinuria (greater than 3.5 g/d), microscopic hematuria, low serum albumin and high serum lipids | urinary fat droplets, oval fat bodies, RTE cells; and epithelial, fatty, and waxy casts |
Minimal Change Disease/Lipid Nephropathy | edema | | heavy proteinuria, transient hematuria | |
Focal Segmental Glomerulosclerosis (FSGS) | edema | | immunoglobulins M and C3, moderate to heavy proteinuria and microscopic hematuria | |
Alport Syndrome | abnormalities in hearing and vision from the age of six, renal insufficiency in later life, progression to nephrotic syndrome and end-stage renal disease | | macroscopic and microscopic hematuria | |
Diabetic Nephropathy/Kimmelstiel-Wilson Disease | | | | |
Acute Tubular Necrosis (ATN) | | | mild proteinuria and microscopic hematuria | RTE cells and RTE cell casts containing tubular fragments consisting of three or more cells; hyaline casts, granular casts, waxy casts and broad casts |
Fanconi Syndrome | | | glycosuria and possible mild proteinuria | |
Nephrogenic Diabetes Insipidus | | low specific gravity and pale yellow color | possible false-negative results for chemical test | |
Renal Glycosuria | | | | |
Urinary Tract Infection (UTI) | | | mild proteinuria and hematuria, increased pH | numerous WBCs and bacteria |
Acute Pyelonephritis | increased urinary frequency, burning sensation while urinating and lower back pain | | mild proteinuria and hematuria | numerous leukocytes and bacteria, WBC casts or bacterial casts |
Chronic Pyelonephritis | increased urinary frequency, burning sensation while urinating and lower back pain | | severe proteinuria and hematuria, and decreased renal concentration | numerous leukocytes and bacteria, WBC casts or bacterial casts, a variety of granular casts, waxy casts, and broad casts |
Acute Interstitial Nephritis (AIN) | edema, fever, skin rashes | oliguria | hematuria, possibly macroscopic mild to moderate proteinuria, decreased renal concentrating ability, possible decrease of glomerular filtration rate | numerous WBCs, and WBC casts without the presence of bacteria |
Renal Failure | edema, and azotemia | oliguria | marked decrease in glomerular filtration (less than 25 mL/min); steadily risin BUN and creatinine values; electrolyte imbalance; isothenuric urine; proteinuria and renal glycosuria | abundant granular casts, waxy casts, and broad casts; either RTE cells and casts, RBCs, WBC casts or urothelial cells |
Renal Lithiasis | severe pain radiating from the lower back to the legs while urinating, urinary obstruction | | microscopic hematuria | crystals |