Membrane Proteins

  • Ampiphikic means they have hydrophobic and hydrophilic domains

  • Transmembrane alpha helices are enriched in amino acids that are non polar

  • Transmembrane protein (rolled up b sheet), found in bacteria

  • Membrane proteins can act as ion channels

  • Can act as transporters

  • Can also act as integrins/adhesions/connexins/claudins to cytoskeleton etc.

  • can act as receptors and enzymes too

  • Glycosylated means lots of sugar residues attached by enzymes to another structure

  • Glycatiion is when sugars are stuck onto proteins without enzymes

  • Glycosylation is important in figuring out blood types

  • Glycoproteins and glycolioids cover the cell in a protective carbohydrate layer.

  • Transport proteins is like carrier proteins, channel proteins r just the normal ones from a level bio

  • Steroid hormones are non polar

  • Collections of beta pleated sheets form a channel thru bilayer.

  • If solute has net charge. Conc gradients and electrical potential difference across membrane will influence transport (inside of membrane usually slightly more negative)

  • You get lot more transport when there’s come gradient and electrical potential gradient

  • Secondary active transport is powered by an ion gradient

  • Uphill solute translocation possible if coupled to ATP hydrolysis

  • Uphill solute transolafion possible if coupled tp downhill movement of an ion. (Seceindsry active transport)