Maternity Final Exam Study Guide😭🤓🫃

Postpartum Care

Vital signs

  • <100.4 F temp during first 24 hrs is normal

  • slight bradycardia

    • tachycardia can indicate infection/blood loss

  • BP should return to normal but watch for s/s preeclampsia/PPH

    • orthostatic HoTN during two days postpartum is normal

Physical Assessment

  • breasts

    • soft on day 1-2

    • filling on day 2-3

    • full, softened for breastfeeding on days 3-5

    • nipples intact skin with no soreness

  • uterus

    • normal findings

      • firm, midline in first 24 hrs

  • perineum

    • monitor for healing if episiotomy or laceration

    • use ice packs/sitz bath

  • lochia

    • rubra

      • first 3-4 days

      • red, bloody

    • serosa

      • 4-10 days

      • pink/brown and contains less blood

    • alba

      • up to six weeks

      • white/yellow with mucus

Gestational Diabetes

Risk factors

  • overweight

  • >25 years old

  • family hx type 2 DM

  • hx GDM

  • polycystic ovarian syndrome

  • hx given birth to baby >9 lbs

  • if no risk factors, test for GDM at 24-28 weeks using one/two-step approach

Maternal risks

  • short term

    • glycosuria

      • high level of glucose in urine increases UTI and vaginitis

      • polyhydramnios

        • abdominal discomfort

        • back pain

        • swelling of lower extremities

        • SOB

        • increased risk for prolapse

      • potential for arrested labor, lacerations, c-section

  • long-term

    • cardiovascular disease

    • metabolic syndrome

    • type 2 DM

    • GDM in future

Fetal risks

  • short-term

    • increase risk for fetal complications from hyperglycemia

      • c-section

      • shoulder dystocia

      • stillbirth

      • preterm birth

      • newborn birth trauma

      • neonatal metabolic/respiratory complications

      • congenital anomalies

      • stillbirth

      • hypoglycemia

      • jaundice

      • fetal growth restriction

      • macrosomia

        • fetus weighs >4000 g

        • extra glucose from blood to fetus, increases insulin response

        • risk for polycythemia, hypoglycemia, respiratory problems, congenital abnormalities

  • long-term

    • fetal neuro/congenital heart defect greater in people dxed with type 1 or 2 DM prior to conception

      • ventricular/atrial septal defect

      • tetralogy of fallot

      • narrow aorta

      • spina bifida

      • microcephaly

    • increased risk for complications later in life

      • obesity

      • HTN

      • metabolic syndrome

      • insulin resistance

Diagnosis

  • fasting blood glucose >126 mg/dl

  • hemoglobin A1C >6.5%

  • random blood glucose >200 mg/dl

  • 2 hr plasma glucose ≥ 200 mg/dl

Treatment

  • 15-15 rule

    • consume 15 grams of simple carbs

    • check blood sugar 15 min later

    • repeat until blood glucose is >70 mg/dl

  • adopt healthy lifestyle, exercise

    • 30 min moderate exercise a day

    • exercise after meals when blood glucose is highest

      • glucose of <140 is optimal after having a meal

  • use artificial sweeteners

    • DO NOT offer saccharin (sweet ‘n low), crosses placenta and shoud be avoided during pregnancy

  • non-starchy veggies, plant protein, lean protein

  • DO NOT take metform/glyburide during pregnancy

  • AVOID

    • hot yoga

    • bouncing/jolting movements

    • pressure on abdomen

    • contact sports

Lifelong monitoring

  • GDM increases risk of DM2 after delivery

  • screen for prediabetes 4-12 weeks postpartum

  • every three years

Physiologic Changes of Pregnancy and Postpartum

Cardiac system

  • increased blood volume and cardiac output

    • will return to pre-pregnancy levels within 2-4 weeks

  • HR increases 10-15bpm

  • decreased BP d/t vasodilation

Respiratory system

  • increased tidal volume by 30-40%

  • growing uterus can cause SOB and increased RR

  • nasal congestion

Integumentary system

  • linea nigra (dark line down abdomen)

  • melasma

  • striae distensae (stretch marks)

  • varicose veins

  • postpartum hairloss

Hematologic system

  • increased blood volume leads to anemia

    • RBC do not increase as much as blood volume

  • risk of clotting d/t hypercoagulability

  • supplement iron postpartum if significant blood loss during pregnancy

GI system

  • slow gastric emptying increased progesterone

    • can lead to constipation

  • heartburn/acid reflux from pressure on stomach d/t uterus

Reproductive system

  • significant expansion of uterus

  • cervical, breast changes

GU system

  • increased bladder pressure cause frequent urination

    • urinary retention/incontinence

  • increased kidney function to accommodate blood volume

Infant Feeding

Breastfeeding

  • anatomy and physiology

    • influenced by estrogen, progesterone, prolactin

    • oxytocin ejects milk from glands and through ducts

  • benefits

    • contains all vitamins required for infant nutrition (except vitamin D)

    • contains antibodies and immune cells

    • increases bonding

    • lowers risk of SIDS

    • foremilk

      • first milk from breast

      • increased protein and carbs

      • decreased fat and calories

      • watery

    • hindmilk

      • near end of feeding

      • increased fat and calories

    • helps contract uterus, lower risk of breast/ovarian cancer

  • starting breastfeeding

    • begin within first hour of life to stimulate bonding and milk production

  • frequency

    • 8-12 times in 24 hrs

    • ensure baby is getting enough breastmilk

      • 6-8 wet diapers and 4 dirty diapers every day

  • cue-based feeding

    • feed based on hunger cues such as:

      • rooting

      • crying

      • smacking lips

      • sucking on hands

Formula feeding

  • contains all vitamins needed d/t supplements

  • modified cow’s milk

    • decreased protein content

    • added carbs, essential nutrients, especially iron

Labor Process and Changes

Changes

First stage

  • begins with regular uterine contraction, ends with complete cervical effacement and dilation

  • latent phase

    • regular, painful uterine contractions that cause cervical change

  • active phase

    • period where greatest rate of cervical dilation occurs

  • care management

    • determine if patient is in true labor (not prodromal labor)

      • assess contractions, cervix, fetus

Second stage

  • begins with full dilation (10 cm)

  • complete effacement

  • ends with infant birth

  • latent phase

    • aka delayed pushing, laboring down, passive descent

  • active phase

    • pushing/urge to bear down

    • ferguson reflex activated when presenting part presses on stretch receptors of pelvic floor

  • care management

    • monitor FHR and pattern

    • utilize valsalva maneuver

Third stage

  • birth of baby until placenta expelled

  • shortest stage of labor

  • placental separation=lengthening of umbilical cord and gush of blood from vagina

Fourth stage

  • begins with expulsion of placenta, lasts until woman stable usually within first hour of birth

  • care management

    • assess physiologic changes to pre-pregnancy status

    • assess for excess blood loss and alterations in vitals/consciousness

Coping

  • assist with breathing techniques, position changes, hydrotherapy, ambulation

  • encourage familial support

Pain control

  • risks

    • opioid dependence/side effects

    • sedation

    • further intervention

  • benefits

    • improved mobility/healing

    • better bonding d/t decreased stress

    • promote rest/recovery

  • preferences

    • respect beliefs and individual pain tolerance

    • may prefer natural methods

    • encouraging asking for pain management

Fetal Monitoring

FHR tracing and uterine activity

  • FSE

    • placed on fetal scalp

    • hard surface

    • away from fontanel

    • not on forehead

    • contraindicated

      • communicable disease

      • hemophilia

      • placenta previa

      • intact membranes

  • IUPC

    • uterus

    • contraindications

      • non-anticipated vaginal delivery

      • placental abruption

      • intact membranes

    • if not reading accurately:

      • reposition patient

      • flush device with NS

      • replace

Categories

Category 1 (Normal)

  • baseline rate of 110-160 bpm

  • moderate baseline variability

  • no late or variable decelerations

  • early decelerations and accelerations may be present or absent

  • indicates a well-oxygenated fetus

  • interventions

    • no intervention needed

Category 3 (Abnormal):

  • absent baseline FHR variability AND any of the following

    • recurrent late decelerations

    • recurrent variable decelerations

    • bradycardia,

    • sinusoidal pattern.

    • Indicates a poorly oxygenated fetus

    • interventions

      • position change

      • O2

      • stop oxytocin

      • administer IV fluids

      • amnioifusion

Category 2 (Indeterminate):

Any FHR pattern that does not fit into Category 1 or 3:

  • moderate variability with recurrent late or variable decelerations

  • minimal variability with recurrent variable decelerations

  • absent variability without recurrent decelerations

  • bradycardia with moderate variability 

  • prolonged decelerations

  • tachycardia

  • indicates fetus that is showing compensatory responses to lack of oxygen

  • interventions

    • position change

    • hydration

    • O2

    • discontinue uterotonics

Newborn Assessment and Care

Assessment

Care

  • immediately after birth

    • assess general appearance and vital signs

      • observe before touching

      • auscultate before palpation in quiet environment

    • measure weight, head circumference, body length

    • assess newborn reflexes

      • root and suck

        • turns head towards stimulus and opens mouth in search of sucking source

      • moro

        • arms extend, abduct, hands open, arm flexion, hands closing

      • babinski

        • hyperextended toes with dorsiflexion of big toe (should disappear after 1 year)

      • START CHEST COMPRESSIONS heart rate <60bpm after advanced airway is placed

      • warm, dry, and stimulate before starting resuscitation

      • use respirations and HR to assess efficacy of resuscitation

  • screenings

    • hyperbilirubinemia (jaundice)

      • newborns should be assessed for jaundice every 8 to 12 hours

      • prevented by adequate feeding

    • universal newborn screening

      • mandated by U.S. law, this screening helps to detect genetic diseases that can cause severe health issues if not treated early.

    • Newborn Hearing Screening is also a part of routine newborn care

Screening for Critical Congenital Heart Disease (CCHD) involves measuring oxygen levels in the right hand and either foot

  • hours after birth

    • check HR, SpO2, temp, apply cardiac monitor if baby is tachypneic with respiratory distress

  • safe discharge criteria

    • stable vitals

    • sufficient feeding

    • normal reflexes

    • sufficient education on newborn care

OB Complications

Uterine rupture

  • manifestations

    • symptomatic disruption and separation of layers of uterus/previous scar

    • mostly occur because of scarred uterus from previous c-section

    • sudden sharp abdominal pain/ripping or tearing sensation

    • bright red vaginal bleeding/signs of hypovolemic shock

    • visible palpation of fetal parts

    • fetal bradycardia

  • risk factors

    • c-section

      • classical/T-shaped incision

    • prior uterine rupture

    • trauma

    • abortion

    • multiparity

    • uterine overdistention

    • malpresentation

    • TOLAC patients

  • interventions

    • start IV fluids

    • transfuse blood products

    • administer oxygen

    • prepare for immediate surgery

    • support family and provide info about tx during emergency

  • maternal effects

    • severe hemorrhage

    • shock

    • hysterectomy

    • infection risk

  • fetal effects

    • abnormal FHR tracing

      • abrupt decrease in FHR

      • late/variable decelerations

      • absent baseline variability

      • tachy/bradycardia

    • loss of fetal station/no fetal descent

    • hypoxia

    • acidosis

  • post complication care

    • monitor for infection

    • assess for PPH

Shoulder dystocia

  • manifestions

    • head is born but anterior shoulder cannot pass under pubic arch

    • cannot be predicted

    • slowing progress of second stage of labor

    • retraction of fetal head (turtle sign)

    • no external rotation

  • risk factors

    • hx shoulder dystocia

    • maternal diabetes/obesity

    • prolonged second stage of labor

    • macrosomia >4000 g

    • maternal pelvic abnormality

  • interventions

    • assume McRoberts maneuver (pull mother’s knees to ears)

    • Gaskins maneuver (mother on hands and knees)

    • suprapubic pressure

    • clavicle fracture

    • symphsiotomy- incision in cartilage between pubic bones to enlarge pelvic opening

    • c-section

    • 1. call for help

    • 2. lower head of bed

    • 3. footstool next to bed

    • 4. McRoberts

    • 5. suprapubic pressure

    • 6. Rubin II maeuver

    • 7. wood’s corkscrew

    • 8. delivery posterior arm

    • 9. gaskin maneuver

  • maternal effects

    • perineal trauma

    • uterine rupture

    • PPH

  • fetal effects

    • hypoxia

    • fractured clavicle

    • erb’s palsy

    • asphyxia

  • post complication care

    • perform neonatal injury assessment

      • examine clavicle/humerus fracture, brachial plexus injuries, asphyxia

    • maternal perineal care

      • detect s/s hemorrhage

      • trauma to vagina, perineum, rectum

Prolapsed cord

  • manifestations

    • cord lies below presenting part of fetus

    • visible/palpable after ROM

    • sudden onset variable/prolonged decels or bradycardia

    • report of feeling cord in vagina

  • risk factors

    • long cord

    • malpresentation (breech or transverse lie)

    • preterm labor

    • polyhydramnios

    • external cephalic version procedure

    • induction using balloon catheter

  • interventions

    • recognize ASAP as hypoxia from cord compression can cause CNS damage/death

    • relieve pressure off cord

      • hold presenting part off umbilical cord

      • assist into lateral position, trendelenburg, knee-chest

  • maternal effects

    • risk for c-section

    • risk for atony/hemorrhage

  • fetal effects

    • severe hypoxia

    • distress

    • bradycardia

    • variable decelerations

  • post complication care

    • neonatal resuscitation

    • monitor for hypoxic encephalopathy

Preterm labor

  • manifestations

    • onset of labor before 37 weeks

    • regular contractions along cervical effacement OR dilation OR both

    • presentation of regular uterine contractions and cervical dilation of at least 2cm

  • risk factors

    • spontaneous PTB

      • infection

      • decreased progesterone

      • maternal/fetal stress

    • indicated PTB

      • preeclampsia

      • multiple gestation

      • placental cause

      • maternal code blue

    • cervical insufficiency

    • positive fFN test

    • look for hypothermia and hypoglycemia for late preterm birth

      • hypoglycemia

        • hypothermia

        • poor feeding

        • jitters

        • apnea

        • lethargy

        • seizures

  • interventions

    • tocolytics to suppress uterine contractions (nifedipine, terbutaline, mg sulfate)

    • betamethasone for fetal lung maturity

    • cerclage before PTB

  • maternal effects

    • risk for anxiety, PPD, PTSD

  • fetal effects

    • respiratory distress syndrome

    • necrotizing enterocolitis

  • post complication care

    • admit to NICU

Meconium-stained fluid

  • manifestations

    • fetal stool in amniotic fluid

    • green, can be thin or thick

  • risk factors

    • hypoxia-induced peristalsis and sphincter relaxation

    • cord compression-induced vagal stimulation

    • breech position

  • interventions

    • suction fetal airway

    • intubation if thick meconium

  • maternal effects

    • chorioamnionitis

    • risk for c-section

    • intrapartum fever

  • fetal effects

    • risk for meconium aspiration syndrome

      • cause severe aspiration pneumonia

  • post complication care

    • before birth

      • assess amniotic fluid for presence of meconium after ROM

      • gather equipment and supplies for neonatal resuscitation

    • immediately after birth

      • assess newborn respiratory effort, HR, muscle tone

      • suction only mouth and nose if WDL vital signs

      • suction trachea if vitals not WDL

Premature rupture of membranes

  • manifestations

    • SROM/leakage of fluid prior to onset of labor at any gestational age

  • risk factors

    • often preceded by infection (chorioamnionitis)

      • bacterial infection of amniotic cavity

      • maternal fever, tachycardia, uterine tenderness, foul odor

    • cervical insufficiency

      • passive/painful dilation of cervix leading to recurrent PTB during second trimester

      • tx with cerclage placement

    • multiple gestation

  • interventions

    • administer magnesium sulfate for 24 hrs for fetal neuroprotection

    • give tocolytic meds or nifedipine to suppress uterine activity

    • give antenatal glucocorticoids (betamethasone) to reduce respiratory distress syndrome, hemorrhage, necrotizing enterocolitis, death

  • maternal effects

    • increased risk of infection

  • fetal effects

    • PTB

    • risk for sepsis

  • post complication care

    • monitor infection

    • monitor FHR

Hypertensive Disorders of Pregnancy

CONTROLLING BLOOD PRESSURE IS THE OPTIMAL INTERVENTION TO PREVENT DEATH FROM STROKE/PREECLAMPSIA

gestational hypertension

development of HTN after week 20 of pregnancy in a woman with previously normal BP

preeclampsia

HTN and proteinuria after 20 weeks of gestation who previously had neither condition

in absence of proteinuria: new-onset HTN with new onset of ANY OF THESE—thrombocytopenia, renal sufficiency (BUN will be doubled), impaired liver function, pulmonary edema, cerebral/visual symptoms

chronic hypertension

present HTN before pregnancy/diagnosed before 20 weeks gestation

superimposed preeclampsia

chronic HTN associated with preeclampsia

Gestational HTN management

  • defined as systolic BP of >140 or diastolic of >90

  • frequent BP and weight measurement

  • report promptly if:

    • increase in BP

    • persistent headache

    • visual change

    • rapid weight gain

    • decreased fetal movement

    • uterine contractions

Preeclampsia

  • HTN and proteinuria after 20 weeks of gestation who previously had neither condition

  • can also develop in postpartum period

  • in absence of proteinuria, preeclampsia may be defined as HTN along with:

    • thrombocytopenia

    • renal sufficiency

    • impaired liver function

    • pulmonary edema

    • cerebral/visual symptoms (blinking stars/dots)

  • risk factors include:

    • preeclampsia hx

    • multifetal gestation

    • chronic HTN

    • pregestational/gestational diabetes

    • SLE

    • obstructive sleep apnea

    • nulliparity

    • BMI >30

    • AMA

    • thrombophilia

    • assisted reproductive technology

  • pathophysiology

    • placenta is root cause

    • begins to resolve after placenta expelled

    • spinal arteries fail to get larger and thicker

      • decreased placental perfusion and endothelial dysfunction= preeclampsia

    • placental ischemia=endothelial cell dysfunction

    • generalized vasospasm=poor tissue perfusion in organ system

  • preeclampsia with severe features

    • thrombocytopenia <100

    • renal insufficiency with elevated serum creatinine >1.1 mg/dl/doubling

    • pulmonary edema

    • headache unresponsive to medication

    • visual disturbances

    • right epigastric pain

    • systolic BP ≥160 or diastolic BP ≥110 at least twice 4 hrs apart

  • gestational age

    • onset prior to 34 weeks is most often severe

      • manage at facility with resources for management of serious maternal/neonatal complications

    • induction at 37 weeks indicated for preeclampsia without severe features

  • management

    • assess BP and edema

    • assess deep tendon reflex/hyperactive reflex (clonus)

    • assess PCR

    • evaluate for these s/s:

      • severe frontal headache

      • epigastric pain (heartburn)

      • right upper quadrant tenderness

      • visual disturbance

    • order CBC, CMP, and PCR labs

Eclampsia

  • onset of seizure activity/coma in preeclamptic patient

  • no hx of preexisting pathology

  • higher in multifetal gestation and women who did not receive prenatal care

  • caused by cerebral edema

  • watch for headache or visual disturbance

Chronic hypertension w/ superimposed preeclampsia

  • dx based on

    • sudden increase in BP that was previously well controlled

    • new-onset/sudden and sustained increase in proteinuria in woman known to have proteinuria before conception/early pregnancy

Signs and symptoms

  • persistent BP >140/90

  • proteinuria if preeclamptic

  • edema

  • severe headache

  • vision change

Treatment

  • turn patient to left lateral position

  • protect airway/administer oxygen (8-10 L/min via nonrebreather)

  • provide padding around bed

Medications

  • labetalol IV

  • nifedipine PO

  • hydralazine IV

  • magnesium sulfate

    • mag sulfate for seizure prophylaxis is indicated for:

      • preeclampsia with severe features

      • severe gestational HTN

      • all cases of severe HTN regardless of classification

    • high Mg levels can causes relaxation of smooth muscle

    • initiate when diagnosed with preeclampsia

    • continue until 24 hrs post delivery or 24 hrs after last seizure if eclamptic

    • dose: 4-6gm loading dose over 20-30 min, then 2gm/hr

    • side effects

      • flushing/warm

      • drowsiness

      • sweating

      • N/V

      • HoTN

      • dizziness

      • headaches

      • slurred speech

      • visual disturbance

      • muscle weakness/decreased DTR

    • toxicity

      • absence/change in DTR

      • decreased LOC

      • SOB

      • decreased respiratory rate

      • persistent HoTN

      • chest pain

      • bradycardia/cardiac arrest

      • Mg greater than 8 mg/dL

    • give 1 g IV calcium gluconate over 3 min for toxicity

    • assessment

      • monitor VS

      • check reflexes

      • monitor I/O (should be >50ml/hr)

      • raise bedrails

      • O2 and suction at bedside

    Meds for chronic HTN during pregnancy

    dose

    labetalol

    200-2400 mg

    first-line in pregnancy, does not reduce uterine blood flow

    nifedipine

    30-90 mg daily

    use with caution with mg sulfate

    methyldopa

    500-2000 mg

    not effective when taken less than three times a day

    hydrochlorothiazide

    12.5-25mg daily

    may be continued if taken before conception but not started as new med in pregnancy

    risk for thrombocytopenia for newborn

medications to avoid

angiotensin-converting enzyme inhibitors (captopril)

angiotensin II receptor antagonist (losartan)

assoc. with birth defects and impaired fetal renal fx

atenolol

assoc. with growth restriction

avoid use in early pregnancy, caution in late pregnancy

HELLP syndrome

  • characterized by:

    • hemolysis

    • elevated liver enzymes

    • low platelet count

  • symptoms

    • upper right abdominal pain

    • N/V

    • headache

    • blurry vision

  • can lead to:

    • liver hematoma/rupture

    • ARDS

    • sepsis

    • hypoxic encephalopathy

    • fetal/maternal death

    • preterm delivery

    • recurrent preeclampsia

    • DIC

  • treatment

    • induction regardless of gestational age

    • monitor CBC and liver enzymes Q6H

    • magnesium infusion

    • BP control

    • early epidural placement

Fetal changes

  • impaired uteroplacental blood flow can cause:

    • IUGR

    • oligohydramnios

    • placental abruption

    • nonreassuring fetal status

      • absent varability

      • tachy/bradycardia

    • preterm labor

Hemorrhagic Disorders

Hemorrhage

  • diagnosis criteria

    • blood loss ≥ 500ml after vaginal birth OR ≥1000ml after c-section

    • 10% drop in Hct

    • signs of hypovolemia

      • tachycardia, HoTN, pallor, AMS

  • treatment

    • fundal massage

    • empty bladder if uterus is displaced

    • IV fluids, blood

    • Bakri balloon

  • laboratory findings

    • decreased hct and hgb

    • decreased fibrinogen

    • decreased platelets

DIC

  • risk factors

  • clinical signs

    • clot formation in microsystem

    • petechiae

    • bleeding from IV site

    • hematuria

    • abnormal bleeding

  • treatment

    • administer blood products (FFP, PT, PRBC)

    • heparin for chronic DIC/when thrombosis suspected

  • lab findings

    • low fibrinogen <100

    • prolonged PT followed by prolonged aPTT

Postpartum Hemorrhage

  • readiness

    • utilize checklist and algorithms

  • recognition

    • measure QBLs

  • response

    • use MTP protocol

  • reporting

    • debrief

Placental Disorders

  • placenta previa

    • implantation of placental near or over cervical os

    • painless, bright red vaginal bleeding

  • placental abruption

    • premature separation of placenta from uterine wall from ruptured maternal vessels in placental bed and subsequent hemorrhage

      • hard board-like abdomen

      • painful with no rest between contractions

      • bleeding can be concealed

  • vasa previa

    • fetal vessels lie over cervical os

    • leads to severe blood loss for fetus

  • placenta accreta—slight penetration on myometrium

  • placenta increta—deep penetration of myometrium

  • placenta percreta—perforation of myometrium and uterine serosa

  • management

    • early delivery

    • hysterectomy in severe cases

Obstetrical Procedures

Types

  • Vacuum extraction and forceps delivery

    • assisted vaginal delivery for prolonged second stage or fetal distress

  • Cesarean section

    • surgical delivery for non-reassuring FHR, fetal malpresentation, maternal complications

  • external cephalic version

    • turn fetus from breech/shoulder presentation to vertex

    • DO NOT PERFORM IF:

      • oligohydramnios

      • previous classical/T-shaped incision

      • nonreassuring FHT

      • nonanticipated vaginal delivery

Indications

  • active maternal infection (herpes for vaginal birth)

  • fetal distress

  • risk of uterine rupture

  • uterine anomaly

  • third trimester bleeding

  • multiple gestation

  • oligohydramnios

  • CPD

  • previous uterine surgery

Contraindications

  • active maternal infection (herpes for vaginal birth)

  • fetal distress

  • risk of uterine rupture

Maternal Sepsis

  • life-threatening complication from infection that includes organ dysfunction

Prevention

  • screening

    • modified early obstetric warning system (MEOWS)

      • identify abnormal criteria within obstetric population

    • triggers include:

      • altered mental status

      • visual disturbances

      • severe headache

      • dyspnea

      • epigastric pain

Diagnosis

  • first step

    • assess vital signs (temperature, HR, RR)

    • parameters adjusted for pregnancy/WBC count

    • obtain within 24 hrs of symptom onset

  • second step

    • evaluate for end-organ injury with lab values

    • assess lactic acid levels

      • labor raises lactic acid

  • MAP <65 mmHg sustained for 15 min after 30ml/kg fluid load directly defines septic shock

  • fetal tachycardia is an early sign of maternal infection

Treatment

  • must begin IMMEDIATELY

  • alert rapid response team

  1. administer broad-spectrum antibiotics without delay

  2. rapid admin of 30ml/kg bolus of crystalloid solution for HoTN or lactate ≥4

  3. obtain blood cultures before abx if possible

  4. give vasopressors for HoTN that persists after fluid resuscitation to maintain MAP ≥65

Lab findings

mental status

temperature

heart rate

respiratory rate

WBC count

FHR

Nonpregnant

altered

>38C or <36C

>90 bpm

>20

>12,000 or <4000 or >10% bands

N/A

Pregnant

altered

>38C or <36C

>110 bpm

>24

>16,000 or <4000 or >10% bands

>160 bpm

  • bilirubin >2

  • lactic acid >2

Causes

  • antepartum

    • septic abortion

    • pneumonia/flu

    • pyelonephritis

    • cholecystitis

  • intrapartum

    • chorioamnionitis

    • pyelonephritis

    • pneumonia

  • postpartum

    • endometritis

      • infection of uterine lining

    • wound infection

      • often develop after discharge

    • mastitis

    • pyelonephritis

    • pneumonia

Hemodynamics

  • vasodilation/reduced systemic vascular resistance

  • HoTN

  • tacycardia

  • myocardial depression

Clinical goals

  • optimize preload

  • maintain MAP ≥65

  • maintain urine out put ≥0.5 ml/kg/hr

  • support O2 transport via inotropic meds

  • abx within 1 hr of sepsis recognition

Birth Injury

Types

  • soft tissue injuries (caput succedaneum, cephalhematoma, petechiae)

  • clavicle fracture from shoulder dystocia

  • brachial plexus (erb’s palsy)

  • lacerations from c-section

Assessments

  • full head to toe

  • check for asymmetry of movement (especially for erb’s palsy)

  • assess reflexes

  • observe for pain response

Treatments

  • surgical intervention

  • monitor jaundice

  • physical therapy for nerve injuries

Fetal Demise

Risks

  • maternal HTN, clotting disorders

  • GDM

  • preeclampsia

  • infection

  • placental insufficiency/complications

  • smoking/alcohol

Recommendations

  • manage chronic conditions

  • iduction of labor

  • D&C for early losses

  • evaluate for maternal clotting factors

  • administer Rhogam if mother is Rh-negative

Emotional support

  • family

    • allow genuine concern/care

    • allow family to talk about baby

    • reassure that they did everything right

    • use baby’s name

  • intrapartum

    • no FHR

    • pain management

    • emotional support

    • pre-birth education

  • bereaved mother

    • physical assessment of breasts, uterus, bladder, bowel, lochia, episiotomy (BUBBLE)

    • education of fetal evaluation/autopsy/genetic testing

    • discharge planning

    • edinburgh scale for PPD

  • infant

    • comfort measures/palliative care

    • spiritual needs

    • creating memories

  • GAD-7 and Edinburgh scale used for perinatal depression and anxiety

Medications

Medication

Route

Dose

Indications

Contraindications/Side Effects

magnesium sulfate

IV

4-6gm loading dose over 20-30 min, then 2gm/hr

preeclampsia with severe features

severe gestational HTN

all cases of severe HTN regardless of classification

  • side effects

    • flushing/warm

    • drowsiness

    • sweating

    • N/V

    • HoTN

    • dizziness

    • headaches

    • slurred speech

    • visual disturbance

    • muscle weakness/decreased DTR

  • toxicity

    • absence/change in DTR

    • decreased LOC

    • SOB

    • decreased respiratory rate

    • persistent HoTN

    • chest pain

    • bradycardia/cardiac arrest

    • Mg greater than 8 mg/dL

labetalol

PO/IV

200-2400mg

first-line in pregnancy for chronic HTN

does not reduce uterine blood flow

tranexamic acid

IV

1 gm

hemorrhage/lacerations

contraindicated in bleeding disorders

methergine (methylergonvine)

PO/IM

0.2 mg

postpartum hemorrhage

contraindicated in HTN

vitamin k

IM/SUBQ

1mg

prevents hemorrhagic disease in newborns

hydralazine

IV

5-10 mg q20 min PRN

acute HTN

nifedipine

PO

30-90 mg daily

chronic HTN

use with caution with mag sulfate

surfactant

endotracheal tube (ET)

neonatal RDS

misoprostol (cytotec)

rectal/vaginal/buccal

800-1000 mcg

postpartum hemorrhage, cervical ripening, induction

fentanyl

IV/IM/TD

25-100 mcg

labor pain

oxytocin (pitocin)

IM/IV

10-30 MU

hemorrhage, stimulate uterine contractions

terbutaline

SUBQ/IV

0.25 mg q20min-q6hrs

suppress uterine contractions (tocolysis)

tachycardia

GDM/hyperglycemia

betamethasone

IM

12mg q24h x 2 doses

fetal lung maturity

Induction of Labor

Methods

  • IV oxytocin

  • amniotomy

Indications

  • indicated when maternal/fetal risks assoc. with continuing pregnancy are as great as the risks assoc. with delivery

    • postterm pregnancy

    • PROM

    • hypertensive disorders

    • DM

    • fetal growth restriction

    • twins

    • chorioamnionitis

    • placental abruption

    • oligohydramnios

    • cholestasis

    • fetal demise

Contradictions

  • active maternal infection (herpes for vaginal birth)

  • fetal distress

  • risk of uterine rupture

  • malpresentation

Risks

  • uterine hyperstimulation

  • increased c-section risk

  • infection

  • PPH

  • umbilical cord prolapse

monochorionic/monamniotic twins are identical who share both a placenta and amniotic sac

  • risk for cord entanglement

  • twin to twin transfusion

PPROM risk factors are vaginal bleeding, STI, chorioamnionitis

4 T’s of hemorrhage

tone

tissue

trauma

thrombin

ALWAYS TX BP OF 160/110

nifedipine po

labetalol iv

hydralazine iv

schedule postpartum visit 4-6 weeks for GDM

assess GTT 4-12 weeks postpartum

infants born between 34 weeks and 36s weeks are considered late preterm

  • risks for hypothermia and hypoglycemia