Pharmacology Final Study Guide

NRS2401 Pharmacology Final Study Guide

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Lehne Ch. 82 and 84: Drugs for Peptic Ulcer and Other GI Drugs

  • Understand the class, MOA, common indications/side effects/re-assessments for the following drug classes.
    • Antacids: magnesium hydroxide, aluminum hydroxide
    • H2 Antagonists: famotidine
    • PPI: pantoprazole
    • Mucosal protectant: Sucralfate
    • Antiemetics: ondansetron, metoclopramide
    • Laxatives: docusate, polyethylene glycol, senna, Bisacodyl

Cumulative Content

Lehne Ch. 1 and 2: Orientation and Application of Pharmacology in Nursing Practice

· Understand the rights to medication administration


Lehne Ch. 4 and 5: Pharmacokinetics /Pharmacodynamics

· Understand the difference between absorption, distribution, metabolism, and excretion with examples.

· Explain why drug doses and responses differ among individuals.

Lehne Ch. 16 and 17: Muscarinic Agents

· Recognize toxic effects of muscarinic agonists and antagonists.

· Describe the MOA, uses, and adverse effects and reassessments for the following medications: Bethanechol, and Oxybutynin

Lehne Ch. 61, 62, 63: Drugs for Thyroid, Hypothalamic, Adrenal Disorders

· Describe the MOA, uses, adverse effects, and reassessments of these medications:

o Levothyroxine, hydrocortisone

Lehne Ch. 60: Drugs for Diabetes

· Distinguish peak, onset, and duration of different types of insulin (rapid, short, intermediate, and long acting).

· Describe the MOA, uses, and adverse effects of biguanide (metformin), sulfonylureas (glipizide & glyburide).

Lehne Ch. 44: Diuretics

· Describe the pharmacologic properties, mechanisms, uses, and adverse effects of loop, thiazide, potassium sparing, and osmotic diuretics.

· Meds to know: furosemide, hydrochlorothiazide, spironolactone, mannitol

Lehne Ch. 20 and 21: Adrenergic Agonists and Antagonists

· Describe the therapeutic and adverse effects of alpha1, alpha2, beta1, beta2, and dopamine receptor activation.

· Differentiate first-generation (nonselective) from second-generation (cardio selective) beta blockers.

o Meds to know:

§ Beta Blockers: Metoprolol, labetalol

§ Alpha Blockers: Tamsulosin

§ Alpha Agonists: Epinephrine

Lehne Ch. 47, 49, 50: Drugs for RAAS, Vasodilators, and anti-HTN

· Describe the MOA, uses, administration instructions, reassessments, and adverse effects of the medications below.

o ACE: Lisinopril

o ARB: Losartan

o Vasodilators: Hydralazine

Drugs for Heart Failure: Lehne Ch. 51

  • Digoxin: Summarize the pharmacologic properties, mechanisms, therapeutic effects, adverse effects, and monitoring considerations for digoxin including management of drug-induced dysrhythmias and toxicity.

Neuro Drugs: Lehne Ch. 24, 26, and 28

  • Understand the class, MOA, common indications/side effects/re-assessments for the following drug classes.
    • Atorvastatin, phenytoin (drug level needed), gabapentin, carbidopa/levodopa

Drugs for Musculoskeletal Disorders: Lehne Ch. 78 and 79

  • Understand the class, MOA, common indications/side effects/re-assessments for the following drug classes.
      1. Allopurinol, and Alendronate